Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Thais de Castro Barbosa"'
Autor:
Melissa L. Borg, Julie Massart, Thais De Castro Barbosa, Adrià Archilla‐Ortega, Jonathon A.B. Smith, Johanna T. Lanner, Jorge Alsina‐Fernandez, Benjamin Yaden, Alexander E. Culver, Håkan K.R. Karlsson, Joseph T. Brozinick, Juleen R. Zierath
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1232-1248 (2021)
Abstract Background Type 2 diabetes and obesity are often seen concurrently with skeletal muscle wasting, leading to further derangements in function and metabolism. Muscle wasting remains an unmet need for metabolic disease, and new approaches are w
Externí odkaz:
https://doaj.org/article/4c0234bc7ba04d1092c8b189c782f2dd
Autor:
Joanne X. Shen, Morgane Couchet, Jérémy Dufau, Thais de Castro Barbosa, Maximilian H. Ulbrich, Martin Helmstädter, Aurino M. Kemas, Reza Zandi Shafagh, Marie‐Adeline Marques, Jacob B. Hansen, Niklas Mejhert, Dominique Langin, Mikael Rydén, Volker M. Lauschke
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract Obesity and type 2 diabetes are strongly associated with adipose tissue dysfunction and impaired adipogenesis. Understanding the molecular underpinnings that control adipogenesis is thus of fundamental importance for the development of novel
Externí odkaz:
https://doaj.org/article/568a4d59aeaf495091d40d5a6daf16a5
Publikováno v:
Molecular Metabolism, Vol 6, Iss 7, Pp 621-630 (2017)
Objective: Parental nutrition and lifestyle impact the metabolic phenotype of the offspring. We have reported that grandpaternal chronic high-fat diet (HFD) transgenerationally impairs glucose metabolism in subsequent generations. Here we determined
Externí odkaz:
https://doaj.org/article/5ef218f7c9aa45de8878faf574cf69d6
Autor:
Thais de Castro Barbosa, Lars R. Ingerslev, Petter S. Alm, Soetkin Versteyhe, Julie Massart, Morten Rasmussen, Ida Donkin, Rasmus Sjögren, Jonathan M. Mudry, Laurène Vetterli, Shashank Gupta, Anna Krook, Juleen R. Zierath, Romain Barrès
Publikováno v:
Molecular Metabolism, Vol 5, Iss 3, Pp 184-197 (2016)
Objectives: Chronic and high consumption of fat constitutes an environmental stress that leads to metabolic diseases. We hypothesized that high-fat diet (HFD) transgenerationally remodels the epigenome of spermatozoa and metabolism of the offspring.
Externí odkaz:
https://doaj.org/article/53c3d652fd614af285600d41d39b1dd2
Autor:
Thais de Castro Barbosa
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
A Arginina (Arg) regula a secreção de GH e insulina, e é o único precursor biológico do NO. Previamente demonstramos que animais tratados cronicamente com Arg (35mg/dia) desenvolvem resistência à insulina (RI), e o presente estudo investigou a
Autor:
Elena Griseti, Mikael Rydén, Dominique Langin, Ez-Zoubir Amri, Niklas Mejhert, Etienne Mouisel, Lucas Massier, Joanne X. Shen, Jérémy Dufau, Thais de Castro Barbosa, Morgane Couchet, Volker M. Lauschke
Publikováno v:
Cell Physiology
Adipocytes are specialized cells with pleiotropic roles in physiology and pathology. Several types of fat cells with distinct metabolic properties coexist in various anatomically defined fat depots in mammals. White, beige, and brown adipocytes diffe
Autor:
Thais de Castro Barbosa, Benjamin C. Yaden, Juleen R. Zierath, Jonathon A. B. Smith, Jorge Alsina-Fernandez, Melissa L. Borg, Julie Massart, Adrià Archilla‐Ortega, Håkan Karlsson, Johanna T. Lanner, Alexander E. Culver, Joseph T. Brozinick
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1232-1248 (2021)
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1232-1248 (2021)
Background Type 2 diabetes and obesity are often seen concurrently with skeletal muscle wasting, leading to further derangements in function and metabolism. Muscle wasting remains an unmet need for metabolic disease, and new approaches are warranted.
Publikováno v:
The FASEB Journal. 33:6269-6280
Paternal preconceptional high-fat diet (HFD) alters whole-body glucose and energy homeostasis over several generations, which may be mediated by altered transcriptomic profiles of metabolic organs. We investigated the effect of paternal HFD on the he
Publikováno v:
Molecular Metabolism
Alm, P S, de Castro Barbosa, T, Barrès, R, Krook, A & Zierath, J R 2017, ' Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle ', Molecular Metabolism, vol. 6, no. 7, pp. 621-630 . https://doi.org/10.1016/j.molmet.2017.05.009
Molecular Metabolism, Vol 6, Iss 7, Pp 621-630 (2017)
Alm, P S, de Castro Barbosa, T, Barrès, R, Krook, A & Zierath, J R 2017, ' Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle ', Molecular Metabolism, vol. 6, no. 7, pp. 621-630 . https://doi.org/10.1016/j.molmet.2017.05.009
Molecular Metabolism, Vol 6, Iss 7, Pp 621-630 (2017)
Objective Parental nutrition and lifestyle impact the metabolic phenotype of the offspring. We have reported that grandpaternal chronic high-fat diet (HFD) transgenerationally impairs glucose metabolism in subsequent generations. Here we determined w
Autor:
Maria Manti, Romina Fornes, Anna Benrick, Daniel P. Andersson, Gianluigi Pironti, Angelica Lindén Hirschberg, Sarah McCann Haworth, Mattias Carlström, Elisabet Stener-Victorin, Thais de Castro Barbosa, Zhengbing Zhuge
Publikováno v:
Journal of the Endocrine Society
Polycystic ovary syndrome (PCOS) is suggested to increase the risk for cardiovascular disease and type 2 diabetes. We hypothesized here that prenatal exposure to dihydrotestosterone (DHT) and/or maternal obesity lead to adverse metabolic and cardiac