Výsledky vyhledávání - "Thais Helena Chaves, Batista"

Association of KLOTHO polymorphisms with clinical complications of sickle cell anemia

Autor: Manuela F. Hazin, Thais Helena Chaves Batista, Gabriela da Silva Arcanjo, Aderson S Araujo, Betânia Lucena Domingues Hatzlhofer, Antonio R. Lucena-Araujo, Diego Arruda Falcão, Jéssica Vitória Gadelha de Freitas Batista, Pablo Ramon Gualberto Cardoso, Maira Galdino da Rocha Pitta, Marcos André Cavalcanti Bezerra, Diego A Pereira-Martins, Igor de Farias Domingos, Fernando Ferreira Costa, Ana Claudia Mendonça dos Anjos, Isabel Weinhäuser

Publikováno v: Annals of Hematology. 100:1921-1927

The clinical and phenotypic heterogeneity of patients with sickle cell anemia (SCA) is influenced by environmental and genetic factors. Several genetic modifiers, such as the KLOTHO (KL) gene, have been associated with SCA clinical outcomes. The KL g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40f3803ddc7dc752fca5574ce5027dd6
https://doi.org/10.1007/s00277-021-04532-w

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Alpha thalassemia, but not βS-globin haplotypes, influence sickle cell anemia clinical outcome in a large, single-center Brazilian cohort

Publikováno v: Annals of Hematology. 100:921-931

Alpha thalassemia and beta-globin haplotype are considered classical genetic disease modifiers in sickle cell anemia (SCA) causing clinical heterogeneity. Nevertheless, their functional impact on SCA disease emergence and progression remains elusive.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8810ea8b501d301689840d84ff5bdbe7
https://doi.org/10.1007/s00277-021-04450-x

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Influence of UGT1A1 promoter polymorphism, α-thalassemia and βs haplotype in bilirubin levels and cholelithiasis in a large sickle cell anemia cohort

Publikováno v: Annals of Hematology. 100:903-911

Hyperbilirubinemia in patients with sickle cell anemia (SCA) as a result of enhanced erythrocyte destruction, lead to cholelithiasis development in a subset of patients. Evidence suggests that hyperbilirubinemia may be related to genetic variations,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::206bab0dc2f6da731d3bb7227211a57f
https://doi.org/10.1007/s00277-021-04422-1

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Interaction between hemoglobin S and N-Baltimore: a case report in Pernambuco, Brazil

Autor: Antonio R. Lucena-Araujo, Thais Helena Chaves Batista, Camila Mabel de Albuquerque Ramos, Gabriela da Silva Arcanjo, Rodrigo Marcionilo Santana, Ana Cláudia Mendeonça dos Anjos, Fernando Ferreira Costa, Marcondes José de Vasconcelos Costa Sobreira, Aderson S Araujo, Marcos André Cavalcanti Bezerra, Dulcineia M. Albuquerque

Publikováno v: Hematology, Transfusion and Cell Therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcfc1475759229c67488e21caa415be
https://doi.org/10.1016/j.htct.2019.02.002

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Alpha thalassemia, but not β

Autor: Betânia Lucena Domingues, Hatzlhofer, Diego Antonio, Pereira-Martins, Igor, de Farias Domingos, Gabriela da Silva, Arcanjo, Isabel, Weinhäuser, Diego Arruda, Falcão, Isabela Cristina Cordeiro, Farias, Jéssica Vitória Gadelha, de Freitas Batista, Luana Priscilla Laranjeira, Prado, Jéssica Maria Florencio, Oliveira, Thais Helena Chaves, Batista, Marcondes José de Vasconcelos Costa, Sobreira, Rodrigo Marcionilo, de Santana, Amanda Bezerra de Sá, Araújo, Manuela Albuquerque, de Melo, Bruna Vasconcelos, de Ancântara, Juan Luiz, Coelho-Silva, Ana Beatriz Lucas, de Moura Rafael, Danízia Menezes, de Lima Silva, Flávia Peixoto, Albuquerque, Magnun Nueldo Nunes, Santos, Ana Cláudia, Dos Anjos, Fernando Ferreira, Costa, Aderson, da Silva Araújo, Antonio Roberto, Lucena-Araújo, Marcos André Cavalcanti, Bezerra

Publikováno v: Annals of hematology. 100(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::759b3a7c91ce543ea24d8fd00b2f2c08
https://pubmed.ncbi.nlm.nih.gov/33586016

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Evaluation of Markers of Intravascular Hemolysis and Endothelial Dysfunction in Sickle Cell Anemia Patients with and without Hydroxyurea Therapy

Autor: Fernando Ferreira Costa, Maria de Fátima Sonati, Rodrigo Marcionilo Santana, Magnun N. N. Santos, Thais Helena Chaves Batista, Igor de Farias Domingos, Marcos André Cavalcanti Bezerra, Bidossessi Wilfried Hounkpe, Francine Chenou, Aderson S Araujo, Erich Vinicius De Paula

Publikováno v: Blood. 134:4826-4826

Background: Sickle cell anemia (SCA) is characterized by chronic hemolysis and endothelial dysfunction (ED). Plasma hemoglobin (pHb) and its heme component released from intravascular hemolysis (IH) are among the most important factors contributing t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::929d017d8cd7aced17289d545f73c37d
https://doi.org/10.1182/blood-2019-131169

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Up-Regulation of Mir-21 and Mir-130a and Serum Leptin Levels on Leg Ulcers Development in Sickle Cell Anemia

Autor: Luydson Richardson Silva Vasconcelos, Mario J.A. Saad, Marcondes José de Vasconcelos Costa Sobreira, Aderson S Araujo, Antonio R. Lucena-Araujo, Diego A Pereira-Martins, Diego Arruda Falcão, Gabriela da Silva Arcanjo, Thais Helena Chaves Batista, Fernando Ferreira Costa, Bruno M. Carvalho, Marcos André Cavalcanti Bezerra, Rodrigo Marcionilo Santana

Publikováno v: Blood. 134:975-975

Introduction: Leg ulcers (LUs) are a cutaneous complication of sickle cell anemia (SCA), whose etiology is considered multifactorial. In the search for new candidates for modulators of SCA clinical events, recent evidence suggests the significant rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7d61d21b52d554afcac02ac6030d39b
https://doi.org/10.1182/blood-2019-132043

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