Výsledky vyhledávání - "Thais C, Lima"

Evaluation of lignan-loaded poly(ε-caprolactone) nanoparticles: synthesis, characterization, in vivo and in silico schistosomicidal activity

Autor: Thais C. Lima, Lizandra G. Magalhães, Lucas A. de L. Paula, Wilson R. Cunha, Ana H. Januário, Patricia M. Pauletti, Jairo K. Bastos, Fransergio F. dos Santos, Moacir R. Forim, Rosangela S. Laurentiz, Fernanda A. Santos, Renato P. Orenha, Renato L. T. Parreira, Carlos A. Fuzo, Eduardo F. Molina, Mario F. C. Santos, Márcio L. A. e Silva

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2022-04-29T08:38:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Lignan dinitrohinokinin displays important biological activities, which led to the preparation of its poly-ε-caprolactone nanoparticles. Kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2d1b875675b6852652db68766a9d1a
https://doi.org/10.1080/14786419.2021.2021515

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In vivo schistosomicidal activity of (±)-licarin A-loaded poly(ε-caprolactone) nanoparticles

Autor: Thais C. Lima, Lizandra G. Magalhães, Lucas A. de L. Paula, Wilson R. Cunha, Ana H. Januário, Patricia M. Pauletti, Jairo K. Bastos, Hallana Alves Mnuquian, Moacir R. Forim, Raquel P. Morais-Urano, Rosangela S. Laurentiz, Wellington N. Tondato, Eduardo F. Molina, Mario F.C. Santos, Márcio L.A. e Silva

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Schistosomiasis mansoni is an infectious parasitic disease caused by worms of the genus Schistosoma, and praziquantel (PZQ) is the medication available for the treatment of schistosomiasis. However, the existence of resistant strains reinforces the n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c891b98eb67dc0b2043614776cb2b547
https://pubmed.ncbi.nlm.nih.gov/35998724

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Evaluation of lignan-loaded poly(ε-caprolactone) nanoparticles: synthesis, characterization

Autor: Thais C, Lima, Lizandra G, Magalhães, Lucas A de L, Paula, Wilson R, Cunha, Ana H, Januário, Patricia M, Pauletti, Jairo K, Bastos, Fransergio F, Dos Santos, Moacir R, Forim, Rosangela S, Laurentiz, Fernanda A, Santos, Renato P, Orenha, Renato L T, Parreira, Carlos A, Fuzo, Eduardo F, Molina, Mario F C, Santos, Márcio L A E, Silva

Publikováno v: Natural product research. 36(22)

Lignan dinitrohinokinin displays important biological activities, which led to the preparation of its poly-ε-caprolactone nanoparticles. Kinetics analysis revealed initially slow drug release followed by a prolonged, moderate release 6 h later due t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8c771f53738c284536b0b0fc5219a0e
https://pubmed.ncbi.nlm.nih.gov/34963393

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In Vivo and in Silico Trypanocidal Activity Evaluation of (−)‐Cubebin Encapsulated in PLGA Microspheres as Potential Treatment in Acute Phase

Autor: Renato L. T. Parreira, Nayara Bruna dos Reis Neres, Renato Pereira Orenha, Daniele da Silva Ferreira, Thais C. Lima, Viviane Rodrigues Esperandim, Márcio Luis Andrade e Silva, Daniel Montagnini, Eduardo F. Molina, Wilson Roberto Cunha

Publikováno v: Chemistry & Biodiversity. 18

In this study, the trypomastigotes of a Y strain of Trypanosoma cruzi were inoculated intraperitoneally into male BALB/c mice weighing approximately 25 g each, which were divided into groups for evaluation of the trypanocidal activity. For the treatm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3b11ef5a1bd8494ed89521c7556f5e
https://doi.org/10.1002/cbdv.202100052

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In vitro schistosomicidal activity of the lignan (−)-6,6′-dinitrohinokinin (DNHK) loaded into poly(lactic-co-glycolic acid) nanoparticles against Schistosoma mansoni

Autor: Wilson Roberto Cunha, Thais C. Lima, Fernanda Rafacho Badoco, Márcio Luis Andrade e Silva, Lizandra Guidi Magalhães, Eduardo F. Molina, Rodrigo Lucarini, Viviane Rodrigues Esperandim, Priscilla Paiva Luz, Liziane Marçal, Jairo Kenupp Bastos, Rosangela da Silva de Laurentz, Regiane Godoy de Lima, Emerson H. de Faria

Publikováno v: Pharmaceutical Biology, Vol 55, Iss 1, Pp 2270-2276 (2017)

Context: (−)-6,6′-Dinitrohinokinin (DNHK) display remarkable antiparasitic activity and was, therefore, incorporated into a nanoparticle formulation. Objective: Incorporation of DNHK in poly lactic-co-glycolic acid (PLGA) nanoparticles aiming to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9726dca278ee6769c0db530efa50c564

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In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (−)-cubebin derivatives (−)-hinokinin and (−)-O-benzylcubebin

Autor: Patrícia Mendonça Pauletti, Guilherme Venâncio Símaro, Alexandre Luiz Souto Borges, Karla F. Andriani, Ana Helena Januário, Renato L. T. Parreira, Rodrigo Lucarini, Alice Monique Pacheco Souza, Jairo Kenupp Bastos, Márcio Luis Andrade e Silva, Wilson Roberto Cunha, Thais C. Lima, Angélica Campos Cintra Volpe, Carolina Quireza Jacob de Andrade, Giovanni F. Caramori, Rosangela da Silva Laurentiz, Valéria A. Conforti, Carly Henrique Gambeta Borges

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2018-12-11T16:45:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4432695a6357d7eb15414aec2dee35
https://doi.org/10.1016/j.bmcl.2016.11.081

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Effects of (−)-6,6′-dinitrohinokinin on adult worms of Schistosoma mansoni: a proteomic analyses

Autor: Ana Patrícia Yatsuda, Vanderlei Rodrigues, Lizandra Guidi Magalhães, Gustavo Garcia, Rosangela da Silva de Laurentiz, Márcio Luis Andrade e Silva, Thais C. Lima, Enyara Rezende Morais, Daniela de Paula Aguiar, Luiz Gustavo Gardinassi, Renato Graciano de Paula, Wilson Roberto Cunha, Ademar A. da Silva Filho, Jairo Kenupp Bastos

Publikováno v: Revista Brasileira de Farmacognosia, Vol 26, Iss 3, Pp 334-341 (2016)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Revista Brasileira de Farmacognosia, Volume: 26, Issue: 3, Pages: 334-341, Published: JUN 2016
Revista Brasileira de Farmacognosia v.26 n.3 2016
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
Revista Brasileira de Farmacognosia, Vol 26, Iss 3, Pp 334-341

Made available in DSpace on 2022-04-28T19:03:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-05-01 Schistosomiasis, a chronic disease that affects million people worldwide, is caused by trematodeflukes of the genus Schistosoma. The lack of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269f6a8a63abe6ea51a29d540987b7d0

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In vitro activities of Pfaffia glomerata root extract, its hydrolyzed fractions and pfaffic acid against Trypanosoma cruzi trypomastigotes

Autor: Antônio Eduardo Miller Crotti, Eduardo J. Crevelin, Ana C. Pereira, Thais C. Lima, Viviane Rodrigues Esperandim, Márcio Luis Andrade e Silva, Patrícia Mendonça Pauletti, Jairo Kenupp Bastos, Vera Lúcia Garcia Rehder, Wilson Roberto Cunha, Daniele da Silva Ferreira, Ana Helena Januário, Guilherme Venâncio Símaro

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

This paper reports on the in vitro activity of the hydroalcoholic extract of P. glomerata roots, its hydrolyzed fractions, and pfaffic acid against Trypanosoma cruzi. The hydroalcoholic extract obtained from dried, milled P. glomerata roots was submi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35346d1e21a188d93de41fc35d7e0ea3

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Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens

Autor: Tereza Cristina Melo de Brito Carvalho, Eveline S. Costa, A. C. Pereira, V. A. Almeida, Ademar A. da Silva Filho, Jairo Kenupp Bastos, Vanessa de Andrade Royo, Thais C. Lima, Niege Araçari Jacometti Cardoso Furtado, R. Silva, H. S. Coímbra, A. H. C. Vinhólis, Márcio Luis Andrade e Silva, Wilson Roberto Cunha, Carlos Henrique Gomes Martins

Publikováno v: Phytotherapy research : PTR. 21(5)

The activities of the crude ethanol extract from Piper cubeba seeds, (-)-cubebin and its semi-synthetic derivatives were evaluated against oral pathogens. The crude ethanol extract was more active against Streptococcus salivarius (MIC value of 80 mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1d295d1b0fdc31cd00bc49b059ba5a
https://pubmed.ncbi.nlm.nih.gov/17236178

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