Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Thais A Costa-Silva"'
Autor:
Fernanda Thevenard, Ivanildo A. Brito, Thais A. Costa-Silva, Andre G. Tempone, João Henrique G. Lago
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Natural products are a promising source of new compounds with a wide spectrum of pharmacological properties, including antiprotozoal activities. Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is one of several neglected
Externí odkaz:
https://doaj.org/article/7cbff58409cb462d95b7825e05ca3238
Autor:
Thalita S. Galhardo, Anderson K. Ueno, Wagner A. Carvalho, Thais A. Costa-Silva, Marina M. Gonçalves, Mariana B. Abiuzi, Andre G. Tempone, João Henrique G. Lago, Dalmo Mandelli, Cedric Fischmeister, Christian Bruneau
Publikováno v:
Catalysts, Vol 13, Iss 7, p 1097 (2023)
Ruthenium-catalyzed cross metathesis using biseugenol (1) with electron-deficient olefins methyl (2a) and ethyl (2b) acrylates, acrylic acid (2c), acrylonitrile (2d), and methyl methacrylate (2e) derivatives have been conducted to afford respective d
Externí odkaz:
https://doaj.org/article/cbf0e6ef7d3043e9b0b3b57bfaa17c95
Autor:
Geanne A Alves Conserva, Luis M Quirós-Guerrero, Thais A Costa-Silva, Laurence Marcourt, Erika G Pinto, Andre G Tempone, João Paulo S Fernandes, Jean-Luc Wolfender, Emerson F Queiroz, João Henrique G Lago
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247334 (2021)
EtOH extracts from the leaves and twigs of Nectandra oppositifolia Nees & Mart. shown activity against amastigote forms of Trypanosoma cruzi. These extracts were subjected to successive liquid-liquid partitioning to afford bioactive CH2Cl2 fractions.
Externí odkaz:
https://doaj.org/article/28fee4cc4c4f4c10a111249964cad818
Autor:
Ivanildo A. Brito, Fernanda Thevenard, Thais A. Costa-Silva, Samuel S. Oliveira, Rodrigo L. O. R. Cunha, Emerson A. de Oliveira, Patricia Sartorelli, Rafael C. Guadagnin, Maiara M. Romanelli, Andre G. Tempone, João Henrique G. Lago
Publikováno v:
Molecules, Vol 27, Iss 3, p 893 (2022)
As part of our continuous studies involving the prospection of natural products from Brazilian flora aiming at the discovery of prototypes for the development of new antiparasitic drugs, the present study describes the isolation of two natural acetyl
Externí odkaz:
https://doaj.org/article/531831dd09e145699112039faad91c0d
Autor:
Simone S Grecco, Thais A Costa-Silva, Fernanda S Sousa, Stefano B Cargnelutti, Eric Umehara, Poliana S Mendonça, Andre G Tempone, Joao Henrique G Lago
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-7 (2018)
Abstract Background The therapeutic arsenal for the treatment of Leishmaniasis is limited and includes toxic compounds (antimonials, amphotericin B, pentamidine and miltefosine). Given these aspects, the search for new compounds based on floristic bi
Externí odkaz:
https://doaj.org/article/5bf6d7d8675745a798591aac3e75d532
Autor:
Sheila C. Araujo, Fernanda S. Sousa, Thais A. Costa-Silva, Andre G. Tempone, João Henrique G. Lago, Kathia M. Honorio
Publikováno v:
Molecules, Vol 26, Iss 14, p 4116 (2021)
In the present study, the phytochemical study of the n-hexane extract from flowers of Nectandra leucantha (Lauraceae) afforded six known neolignans (1–6) as well as one new metabolite (7), which were characterized by analysis of NMR, IR, UV, and ES
Externí odkaz:
https://doaj.org/article/e1608972fd93474f8aedfc60e2fffdd4
Autor:
Rodrigo de Souza Miranda, Bárbara da Silva Mascarenhas Jesus, Sandra Regina Silva Luiz, Cristina Borges Viana, Camila Rodrigues Adão Malafaia, Fabiana de Souza Figueiredo, Tatiane dos Santos Conceição Carvalho, Matheus Lopes Silva, Vinicius Silva Londero, Thais Alves Costa‐Silva, João Henrique Ghilardi Lago, Roberto Carlos Campos Martins
Publikováno v:
Phytotherapy Research. 36:1459-1506
Terpenes are one of the most abundant classes of secondary metabolites produced by plants and can be divided based on the number of isoprene units (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166c4a4fbe897f99eb959507d92522dc
https://doi.org/10.1002/ptr.7359
https://doi.org/10.1002/ptr.7359
Autor:
Sheila Cruz Araujo, Rafaela Molina de Angelo, Henrique Barbosa, Thais Alves Costa-Silva, André Gustavo Tempone, João Henrique Ghilardi Lago, Kathia Maria Honorio
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62a3e2aa435f36616388ab7d67408c4
Autor:
Erica V. de Castro Levatti, Thais A. Costa-Silva, Thiago R. Morais, João Paulo S. Fernandes, João Henrique G. Lago, Andre G. Tempone
Publikováno v:
Biochimie.
Natural metabolites present an extraordinary chemo-diversity and have been used as the inspiration for new drugs. Considering the need for new treatments against the neglected parasitic disease leishmaniasis, three semi-synthetic derivatives of natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45373fa64eb643f9ed2f00c00e5e872
https://pubmed.ncbi.nlm.nih.gov/36586562
https://pubmed.ncbi.nlm.nih.gov/36586562
Autor:
Fernanda F. Camilo, Andre G. Tempone, Andrea N. L. Batista, João Henrique G. Lago, Larissa V.F. Oliveira, Vinicius S. Londero, João M. Batista, João Batista Baitello, Guilherme Medeiros Antar, Thais A. Costa-Silva
Publikováno v:
Journal of Natural Products. 84:1489-1497
Twigs of Nectandra barbellata were extracted using a solution of the ionic liquid 1-butyl-3-methylimidazolium bromide (BMImBr) in H2O, assisted by microwave (MAE). After successive chromatographic steps, one sesquiterpene, costic acid, and three new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37c35fd2c1151afac0004d612ca45be7
https://doi.org/10.1021/acs.jnatprod.0c01303
https://doi.org/10.1021/acs.jnatprod.0c01303