Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Thaila Fernanda Dos Reis"'
Autor:
Jacob L. Steenwyk, Sonja Knowles, Rafael W. Bastos, Charu Balamurugan, David Rinker, Matthew E. Mead, Christopher D. Roberts, Huzefa A. Raja, Yuanning Li, Ana Cristina Colabardini, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Adiyantara Gumilang, María Almagro-Molto, Alexandre Alanio, Dea Garcia-Hermoso, Endrews Delbaje, Laís Pontes, Camila Figueiredo Pinzan, Angélica Zaninelli Schreiber, David Canóvas, Rafael Sanchez Luperini, Katrien Lagrou, Egídio Torrado, Fernando Rodrigues, Nicholas H. Oberlies, Xiaofan Zhou, Gustavo H. Goldman, Antonis Rokas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cryptic fungal pathogens pose disease management challenges due to their morphological resemblance to known pathogens. Here, we investigated the genomes and phenotypes of 53 globally distributed isolates of Aspergillus section Nidulantes fun
Externí odkaz:
https://doaj.org/article/5b9dafe24b2b40d18c7832764b5d79b9
Autor:
David C. Rinker, Thomas J. C. Sauters, Karin Steffen, Adiyantara Gumilang, Huzefa A. Raja, Manuel Rangel-Grimaldo, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Endrews Delbaje, Jos Houbraken, Gustavo H. Goldman, Nicholas H. Oberlies, Antonis Rokas
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Fungal pathogens exhibit extensive strain heterogeneity, including variation in virulence. Whether closely related non-pathogenic species also exhibit strain heterogeneity remains unknown. Here, we comprehensively characterized the pathogeni
Externí odkaz:
https://doaj.org/article/c85380d1268244839d8888e033552685
Autor:
Thaila Fernanda dos Reis, Camila Diehl, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Gustavo H. Goldman
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Aspergillus fumigatus is the primary etiological agent of aspergillosis. Here, we show that the host defense peptide mimetic brilacidin (BRI) can potentiate ibrexafungerp (IBX) against clinical isolates of A. fumigatus. BRI + IBX can inhibit
Externí odkaz:
https://doaj.org/article/f26703b665b147d39c6bf4c57affb655
Autor:
Camila Diehl, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Endrews Delbaje, Laura C. García Carnero, Eddy Sánchez-León, Kabir Bhalla, James W. Kronstad, Dong-gyu Kim, Tamara L. Doering, Sondus Alkhazraji, Nagendra N. Mishra, Ashraf S. Ibrahim, Mami Yoshimura, Luis Alberto Vega Isuhuaylas, Lien Thi Kim Pham, Yoko Yashiroda, Charles Boone, Thaila Fernanda dos Reis, Gustavo H. Goldman
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal diseases, generally characterized by meningitis. There is a limited and not very effective number of drugs available to combat this disease. In this manuscript,
Externí odkaz:
https://doaj.org/article/e7e096fb2e1e45db88ee688644d28cb3
Autor:
Patrícia Alves de Castro, Camila Figueiredo Pinzan, Thaila Fernanda dos Reis, Clara Valero, Norman Van Rhijn, Carla Menegatti, Ivan Lucas de Freitas Migliorini, Michael Bromley, Alastair B. Fleming, Aimee M. Traynor, Özlem Sarikaya-Bayram, Özgür Bayram, Iran Malavazi, Frank Ebel, Júlio César Jerônimo Barbosa, Taícia Fill, Monica Tallarico Pupo, Gustavo H. Goldman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Aspergillus fumigatus is a saprophytic fungus that can cause a variety of human diseases known as aspergillosis. Mycotoxin gliotoxin (GT) production is important for its virulence and must be tightly regulated to avoid excess production and
Externí odkaz:
https://doaj.org/article/1fe2f63fd7f8410dbf26ab5e774b6588
Autor:
Thaila Fernanda dos Reis, Patrícia Alves de Castro, Rafael Wesley Bastos, Camila Figueiredo Pinzan, Pedro F. N. Souza, Suzanne Ackloo, Mohammad Anwar Hossain, David Harold Drewry, Sondus Alkhazraji, Ashraf S. Ibrahim, Hyunil Jo, Jorge D. Lightfoot, Emily M. Adams, Kevin K. Fuller, William F. deGrado, Gustavo H. Goldman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal drug resistance, novel strategies are urgently needed to combat life-threatening fungal diseases. Here, we identify the host defense peptide mimetic, bri
Externí odkaz:
https://doaj.org/article/95f2a58a934d446abc7358a90c1dec91
Autor:
Relber Aguiar Gonçales, Igor Godinho Portis, Thaila Fernanda dos Reis, Luiz Roberto Basso Júnior, Roberto Martinez, Heng Zhu, Maristela Pereira, Célia Maria de Almeida Soares, Paulo Sergio Rodrigues Coelho
Publikováno v:
Frontiers in Fungal Biology, Vol 4 (2023)
In fungal pathogens the cell wall plays an important role in host-pathogen interactions because its molecular components (e.g., polysaccharides and proteins) may trigger immune responses during infection. GPI-anchored proteins represent the main prot
Externí odkaz:
https://doaj.org/article/4e135dd8e7fa4b268cb0663f0a957d29
Autor:
Rafael Wesley Bastos, Daniel Akiyama, Thaila Fernanda dos Reis, Ana Cristina Colabardini, Rafael Sanchez Luperini, Patrícia Alves de Castro, Regina Lúcia Baldini, Taícia Fill, Gustavo H. Goldman
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT In cystic fibrosis (CF), mucus plaques are formed in the patient’s lungs, creating a hypoxic condition and a propitious environment for colonization and persistence of many microorganisms. There is clinical evidence showing that Aspergillu
Externí odkaz:
https://doaj.org/article/384f683469a84143909439bcbe4733e9
Autor:
Gabriela Lopes Fernandes, Ana Paula Miranda Vieira, Marcelle Danelon, Nayara Gonçalves Emerenciano, Andresa Aparecida Berretta, Andrei Felipe Moreira Buszinski, Juliana Issa Hori, Mikhael Haruo Fernandes de Lima, Thaila Fernanda dos Reis, Jessica Aparecida de Lima, Alberto Carlos Botazzo Delbem, Sónia Carina Morais da Silva, Debora Barros Barbosa
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1477 (2022)
This study investigated the anti-caries and anti-inflammatory effects of mouthwash formulations containing Punica granatum (pomegranate) peel extract (PPE), sodium-trimetaphosphate, and low concentrations of fluoride. PPE was characterized using high
Externí odkaz:
https://doaj.org/article/1793bc6067fe48558a58514270677ea5
Autor:
Laure Nicolas Annick Ries, Patricia Alves de Castro, Lilian Pereira Silva, Clara Valero, Thaila Fernanda dos Reis, Raquel Saborano, Iola F. Duarte, Gabriela Felix Persinoti, Jacob L. Steenwyk, Antonis Rokas, Fausto Almeida, Jonas Henrique Costa, Taicia Fill, Sarah Sze Wah Wong, Vishukumar Aimanianda, Fernando José Santos Rodrigues, Relber A. Gonçales, Cláudio Duarte-Oliveira, Agostinho Carvalho, Gustavo H. Goldman
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Aspergillus fumigatus is a major opportunistic fungal pathogen of immunocompromised and immunocompetent hosts. To successfully establish an infection, A. fumigatus needs to use host carbon sources, such as acetate, present in the body fluids
Externí odkaz:
https://doaj.org/article/0159b3f7f75a4c6cb40eb25bbdc84201