Iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles accelerates drug release, decreasing their targeting effect to hair follicles

Autor: Breno N. Matos, Larissa M. A. Melo, Maíra N. Pereira, Thaiene A. Reis, Marcílio Cunha-Filho, Taís Gratieri, Guilherme M. Gelfuso

Publikováno v: Química Nova, Vol 40, Iss 2, Pp 154-157

The experiments described in this paper tested the hypothesis whether iontophoresis applied on a chitosan nanoparticle formulation could combine the enhanced drug accumulation into the follicular casts obtained using iontophoresis and the sustained d

Externí odkaz: https://doaj.org/article/35f59d219bbd426e8001c81e6031bdb0

Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies

Autor: Thaiene Avila Reis, Ana Elise Jaculi, Rubens da Costa Alves, Tais Gratieri, Ricardo Bentes Azevedo, Graziella Anselmo Joanitti, Guilherme Martins Gelfuso, Marcilio Cunha-Filho

Publikováno v: Journal of Analytical Methods in Chemistry, Vol 2018 (2018)

Considering the feasibility of the aluminum phthalocyanine chloride (AlPcCl) application in the topical photodynamic therapy of cutaneous tumors and the lack of HPLC methods capable of supporting skin permeation experiments using this compound, the a

Externí odkaz: https://doaj.org/article/2b6e9e50f6414fe9befba656da2d42e2

Oxaliplatin preformulation studies for the development of innovative topical drug delivery systems

Autor: Eliana Martins Lima, Thaiene Avila Reis, Juliano A. Chaker, Marcilio Cunha-Filho, Guilherme M. Gelfuso, Breno N. Matos, Tais Gratieri

Publikováno v: Journal of Thermal Analysis and Calorimetry. 130:1671-1681

This paper presents experiments carried out to assess physicochemical characteristics of oxaliplatin (OXPt) and to determine its compatibility with the polymeric matrices with most relevance in development of topical drug delivery systems (DDS). Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4052f1c6d425fae7c25b5946ca6f9c6
https://doi.org/10.1007/s10973-017-6413-2

Influence of monoolein on progesterone transdermal delivery

Autor: Guilherme Gelfuso, Thaiene Avila Reis, Wanessa de Souza Cardoso Quintão, Breno N. Matos, Tais Gratieri, Lívia Cristina Lira de Sá Barreto

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 4, Pp 923-929 (2015)
Brazilian Journal of Pharmaceutical Sciences; Vol. 51 No. 4 (2015); 923-929
Brazilian Journal of Pharmaceutical Sciences; Vol. 51 Núm. 4 (2015); 923-929
Brazilian Journal of Pharmaceutical Sciences; v. 51 n. 4 (2015); 923-929
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Volume: 51, Issue: 4, Pages: 923-929, Published: DEC 2015

This work aimed to investigate in vitro the influence of monoolein (MO) on progesterone (PG) transdermal delivery and skin retention. Information about the role of MO as an absorption enhancer for lipophilic molecules can help on innovative product d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3fd8c1750dcf7883dca9850b24dea9
https://doi.org/10.1590/s1984-82502015000400018

Development and Validation of a Simple and Selective Analytical HPLC Method for the Quantification of Oxaliplatin

Autor: Guilherme M. Gelfuso, Breno N. Matos, Thaiene Avila Reis, Tais Gratieri, Marcilio Cunha-Filho, Paula M. Oliveira

Publikováno v: Journal of Chemistry, Vol 2015 (2015)

Considering that currently published oxaliplatin (OXPt) analytical methods require complex procedures and equipment, the objective of this paper was to present the validation of a simple, rapid, precise, and specific isocratic HPLC method for quantif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687753ec8892d6a4929501419d1eba9d
https://doi.org/10.1155/2015/812701