Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Thai Leong Yap"'
Autor:
Thai Leong Yap, Shin Yee Hong, Jun Hui Soh, Lekha Ravichandraprabhu, Vanessa W.X. Lim, Hsi-Min Chan, Tommy Z.X. Ong, Ying Ping Chua, Shi En Koh, Huajing Wang, Yee Sin Leo, Jackie Y. Ying, William Sun
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 5, Pp 1427-1437 (2021)
Dengue virus (DENV) and Zika virus (ZIKV) belong to the Flaviviridae family of viruses spread by Aedes aegypti mosquitoes in tropical and subtropical areas. Accurate diagnostic tests to differentiate the 2 infections are necessary for patient managem
Externí odkaz:
https://doaj.org/article/38db523af6954e4282fd3a06a5c733da
Autor:
Lekha Ravichandraprabhu, Shi En Koh, Huajing Wang, Yee Sin Leo, William Sun, Hsi-Min Chan, Ying Ping Chua, Shin Yee Hong, Jackie Y. Ying, Tommy Z.X. Ong, Vanessa Weixun Lim, Jun Hui Soh, Thai Leong Yap
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 27, Iss 5, Pp 1427-1437 (2021)
Emerging Infectious Diseases, Vol 27, Iss 5, Pp 1427-1437 (2021)
Dengue virus (DENV) and Zika virus (ZIKV) belong to the Flaviviridae family of viruses spread by Aedes aegypti mosquitoes in tropical and subtropical areas. Accurate diagnostic tests to differentiate the 2 infections are necessary for patient managem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1327311f2b72840694454ae2cf57ed5
https://pubmed.ncbi.nlm.nih.gov/33900180
https://pubmed.ncbi.nlm.nih.gov/33900180
Autor:
Candace M. Pfefferkorn, Marília A. S. Barros, Thai Leong Yap, Zhiping Jiang, Joseph E. Curtis, Ellen Sidransky, Jennifer C. Lee, James M. Gruschus, Frank Heinrich
Publikováno v:
Journal of Biological Chemistry. 290:744-754
Mutations in glucocerebrosidase (GCase), the enzyme deficient in Gaucher disease, are a common genetic risk factor for the development of Parkinson disease and related disorders, implicating the role of this lysosomal hydrolase in the disease etiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81410cdbcfe9ff14379f9508da3beac6
https://doi.org/10.1074/jbc.m114.610584
https://doi.org/10.1074/jbc.m114.610584
Autor:
Ehud Goldin, Thai Leong Yap, Wendy Westbroek, James M. Gruschus, Arash Velayati, Jennifer C. Lee, Nima Moaven, Ellen Sidransky
Publikováno v:
Journal of Biological Chemistry. 286:28080-28088
The presynaptic protein α-synuclein (α-syn), particularly in its amyloid form, is widely recognized for its involvement in Parkinson disease (PD). Recent genetic studies reveal that mutations in the gene GBA are the most widespread genetic risk fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0350a2691fa4076c8d990987dea235
https://doi.org/10.1074/jbc.m111.237859
https://doi.org/10.1074/jbc.m111.237859
Autor:
Subhash G. Vasudevan, Thai Leong Yap, Peter J. Wright, Julien Lescar, Helga Kroschewski, Andrew D. Davidson, Siew Pheng Lim, Rebecca Elizabeth Butcher
Publikováno v:
Journal of Biological Chemistry. 283:19410-19421
The Flavivirus NS5 protein possesses both (guanine-N7)-methyltransferase and nucleoside-2'-O methyltransferase activities required for sequential methylation of the cap structure present at the 5' end of the Flavivirus RNA genome. Seventeen mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db42e86d4c8d7448f639e135200e68d
https://doi.org/10.1074/jbc.m800613200
https://doi.org/10.1074/jbc.m800613200
Autor:
Thai Leong Yap, Bruno Canard, Julien Lescar, T. Xu, Subhash G. Vasudevan, Yen Liang Chen, Hélène Malet, Marie-Pierre Egloff
Publikováno v:
Journal of Virology. 81:4753-4765
Dengue fever, a neglected emerging disease for which no vaccine or antiviral agents exist at present, is caused by dengue virus, a member of the Flavivirus genus, which includes several important human pathogens, such as yellow fever and West Nile vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b36b0a8adedf5bb2cb097912fa51f68
https://doi.org/10.1128/jvi.02283-06
https://doi.org/10.1128/jvi.02283-06
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 63:78-83
Dengue virus, a member of the Flaviviridae genus, causes dengue fever, an important emerging disease with several million infections occurring annually for which no effective therapy exists. The viral RNA-dependent RNA polymerase NS5 plays an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b9f2dafa0518588267cbf56e560896
https://doi.org/10.1107/s1744309106055084
https://doi.org/10.1107/s1744309106055084
Autor:
Jennifer C. Lee, Tatiana K. Rostovtseva, Caroline C. Philpott, Sergey M. Bezrukov, Thai Leong Yap, Philip A. Gurnev, David P. Hoogerheide, Olga Protchenko
Publikováno v:
The Journal of biological chemistry. 290(30)
Participation of the small, intrinsically disordered protein α-synuclein (α-syn) in Parkinson disease (PD) pathogenesis has been well documented. Although recent research demonstrates the involvement of α-syn in mitochondrial dysfunction in neurod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c23dc6c46171e24d5015aec0d908940
https://pubmed.ncbi.nlm.nih.gov/26055708
https://pubmed.ncbi.nlm.nih.gov/26055708
Autor:
Thai Leong Yap, Jennifer C. Lee, David P. Hoogerheide, Philip A. Gurnev, Sergey M. Bezrukov, Olga Protchenko, Tatiana K. Rostovtseva
Publikováno v:
Biophysical Journal. 108(2)
Alpha-synuclein (α-syn), an intrinsically disordered neuronal protein, is implicated in the etiology of Parkinson disease (PD) and a number of other neurodegenerative dementias. Though recent research demonstrates the involvement of α-syn in a vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18476aa4ad7b3cfb13bfdce463b81df3
Autor:
Thai Leong Yap, Stephanie A. Hill, James M. Gruschus, Zhiping Jiang, Ellen Sidransky, Alexander Grishaev, Grzegorz Piszczek, Jennifer C. Lee
Publikováno v:
Biochemical and biophysical research communications. 457(4)
Mutations in the gene for the lysosomal enzyme glucocerebrosidase (GCase) cause Gaucher disease and are the most common risk factor for Parkinson disease (PD). Analytical ultracentrifugation of 8 μM GCase shows equilibrium between monomer and dimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3f04e0ba52bc6e8166a6fe617c7895
https://pubmed.ncbi.nlm.nih.gov/25600808
https://pubmed.ncbi.nlm.nih.gov/25600808