Zobrazeno 1 - 10
of 1 697
pro vyhledávání: '"Thai H"'
Autor:
Tianchu Wang, Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Xia Zhao, Sungho Kim, Liguo Wang, Jeong‐Heon Lee, Huijun Luo, Erik P. Castle, Douglas F. Lake, Thai H. Ho, Keith D. Robertson
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 44-61 (2024)
Histone‐lysine N‐methyltransferase SETD2 (SETD2), the sole histone methyltransferase that catalyzes trimethylation of lysine 36 on histone H3 (H3K36me3), is often mutated in clear cell renal cell carcinoma (ccRCC). SETD2 mutation and/or loss of H
Externí odkaz:
https://doaj.org/article/94fc00dd4ad84cafa77273b4de5bc7d6
Autor:
Christopher J. Ricketts, Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, Ewan A. Gibb, Rehan Akbani, Rameen Beroukhim, Donald P. Bottaro, Toni K. Choueiri, Richard A. Gibbs, Andrew K. Godwin, Scott Haake, A. Ari Hakimi, Elizabeth P. Henske, James J. Hsieh, Thai H. Ho, Rupa S. Kanchi, Bhavani Krishnan, David J. Kwiatkowski, Wenbin Liu, Maria J. Merino, Gordon B. Mills, Jerome Myers, Michael L. Nickerson, Victor E. Reuter, Laura S. Schmidt, C. Simon Shelley, Hui Shen, Brian Shuch, Sabina Signoretti, Ramaprasad Srinivasan, Pheroze Tamboli, George Thomas, Benjamin G. Vincent, Cathy D. Vocke, David A. Wheeler, Lixing Yang, William Y. Kim, A. Gordon Robertson, Paul T. Spellman, W. Kimryn Rathmell, W. Marston Linehan
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113063- (2024)
Externí odkaz:
https://doaj.org/article/53d6204d634d4e3487233c292d61e7e8
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Renal Cell Carcinoma (RCC) is a fatal urological cancer, with one third of patients diagnosed with metastasis, resulting in a 5-year survival of only 12%. Recent advancements in therapies have increased survival in mRCC, but lack efficacy in
Externí odkaz:
https://doaj.org/article/0c63153921214571971ff3caf21c48b5
Autor:
Louis Y. El Khoury, Xiaoyu Pan, Ryan A. Hlady, Ryan T. Wagner, Shafiq Shaikh, Liguo Wang, Mitchell R. Humphreys, Erik P. Castle, Melissa L. Stanton, Thai H. Ho, Keith D. Robertson
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-20 (2023)
Abstract Background Clear cell renal cell cancer (ccRCC), the 8th leading cause of cancer-related death in the US, is challenging to treat due to high level intratumoral heterogeneity (ITH) and the paucity of druggable driver mutations. CcRCC is unus
Externí odkaz:
https://doaj.org/article/584e5c915d604bcbbb2b14be31291f9d
Autor:
Omar Alhalabi, Jianfeng Chen, Yuxue Zhang, Yang Lu, Qi Wang, Sumankalai Ramachandran, Rebecca Slack Tidwell, Guangchun Han, Xinmiao Yan, Jieru Meng, Ruiping Wang, Anh G. Hoang, Wei-Lien Wang, Jian Song, Lidia Lopez, Alex Andreev-Drakhlin, Arlene Siefker-Radtke, Xinqiao Zhang, William F. Benedict, Amishi Y. Shah, Jennifer Wang, Pavlos Msaouel, Miao Zhang, Charles C. Guo, Bogdan Czerniak, Carmen Behrens, Luisa Soto, Vassiliki Papadimitrakopoulou, Jeff Lewis, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Jack Lee, Jack Roth, Stephen Swisher, Ignacio Wistuba, John Heymach, Jing Wang, Matthew T. Campbell, Eleni Efstathiou, Mark Titus, Christopher J. Logothetis, Thai H. Ho, Jianjun Zhang, Linghua Wang, Jianjun Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The deficiency of MTAP, an enzyme of the adenine salvage pathway, occurs in some cancers. Here the authors perform a small cohort phase II clinical trial with metastatic MTAP-deficient urothelial cancer (UC) and show an increased overall response whe
Externí odkaz:
https://doaj.org/article/7a4eb434bab9460784c2152084c1035e
Autor:
Christian U. Blank, Deborah J. Wong, Thai H. Ho, Todd M. Bauer, Carrie B. Lee, Fabiola Bene-Tchaleu, Jing Zhu, Xiaosong Zhang, Edward Cha, Mario Sznol
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 5466-5479 (2021)
This Phase Ib study combined programmed death-ligand 1 inhibitor, atezolizumab, with other immunomodulatory agents in locally advanced and metastatic solid tumors. Arms B-D evaluated atezolizumab plus interferon-α, with/without vascular endothelial
Externí odkaz:
https://doaj.org/article/70fc26b7f9684fb8a5a9798ab958d8a5
Autor:
Thai, H. D., Tuan, H. T.
This paper systematically treats the asymptotic behavior of many (linear/nonlinear) classes of higher-order fractional differential equations with multiple terms. To do this, we utilize the characteristics of Caputo fractional differentiable function
Externí odkaz:
http://arxiv.org/abs/2410.09369
Autor:
Li Zhang, Christopher H. Dietrich, Ye Xu, Zhaofu Yang, Maohua Chen, Thai H. Pham, Cuong C. V. Le, Li Qiao, Masaya Matsumura, Daozheng Qin
Publikováno v:
Ecology and Evolution, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Matsumurasca onukii (Matsuda, R. (1952). Oyo‐Kontyu Tokyo, 8(1): 19–21), one of the dominant pests in major tea production areas in Asia, currently is known to occur in Japan, Vietnam, and China, and severely threatens tea production, qu
Externí odkaz:
https://doaj.org/article/22a8c15e017540f5b95a794e12690e6e
Autor:
Ziad Bakouny, David A. Braun, Sachet A. Shukla, Wenting Pan, Xin Gao, Yue Hou, Abdallah Flaifel, Stephen Tang, Alice Bosma-Moody, Meng Xiao He, Natalie Vokes, Jackson Nyman, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi, Ronan Flippot, Gabrielle Bouchard, John A. Steinharter, Pier Vitale Nuzzo, Miriam Ficial, Miriam Sant’Angelo, Juliet Forman, Jacob E. Berchuck, Shaan Dudani, Kevin Bi, Jihye Park, Sabrina Camp, Maura Sticco-Ivins, Laure Hirsch, Sylvan C. Baca, Megan Wind-Rotolo, Petra Ross-Macdonald, Maxine Sun, Gwo-Shu Mary Lee, Steven L. Chang, Xiao X. Wei, Bradley A. McGregor, Lauren C. Harshman, Giannicola Genovese, Leigh Ellis, Mark Pomerantz, Michelle S. Hirsch, Matthew L. Freedman, Michael B. Atkins, Catherine J. Wu, Thai H. Ho, W. Marston Linehan, David F. McDermott, Daniel Y. C. Heng, Srinivas R. Viswanathan, Sabina Signoretti, Eliezer M. Van Allen, Toni K. Choueiri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Sarcomatoid and rhabdoid tumours are highly aggressive forms of renal cell carcinoma that are also responsive to immunotherapy. In this study, the authors perform a comprehensive molecular characterization of these tumours discovering an enrichment o
Externí odkaz:
https://doaj.org/article/65b689f6ed0042b1ab0807dd0eb2f0de
Autor:
Jeanette E. Eckel-Passow, Huihuang Yan, Matthew L. Kosel, Daniel Serie, Paul A. Decker, Robert B. Jenkins, Brian Costello, Bradley Leibovich, Thai H. Ho, Alexander Parker
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background The four most commonly-mutated genes in clear cell renal cell carcinoma (ccRCC) tumors are BAP1, PBRM1, SETD2 and VHL. And, there are currently 14 known RCC germline variants that have been reproducibly shown to be associated with
Externí odkaz:
https://doaj.org/article/7456cd0cc0074aa8b6550e1aa73a2659