Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Thaddeus J. Wadas"'
Autor:
Amira Zaher, Laura M. Stephens, Ann M. Miller, Stacey M. Hartwig, Jeffrey M. Stolwijk, Michael S. Petronek, Zeb R. Zacharias, Thaddeus J. Wadas, Varun Monga, Joseph J. Cullen, Muhammad Furqan, Jon C. D. Houtman, Steven M. Varga, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pharmacological ascorbate (i.e., intravenous infusions of vitamin C reaching ~ 20 mM in plasma) is under active investigation as an adjuvant to standard of care anti-cancer treatments due to its dual redox roles as an antioxidant in normal tissues an
Externí odkaz:
https://doaj.org/article/ae800cab6bcd4188b2c0616a5d74bf80
Publikováno v:
Molecules, Vol 26, Iss 8, p 2162 (2021)
Bone metastasis remains a major cause of death in cancer patients, and current therapies for bone metastatic disease are mainly palliative. Bone metastases arise after cancer cells have colonized the bone and co-opted the normal bone remodeling proce
Externí odkaz:
https://doaj.org/article/f43170604bae4354a77e011bc443b49b
Autor:
Darpan N. Pandya, Akesh Sinha, Hong Yuan, Lysette Mutkus, Kristina Stumpf, Frank C. Marini, Thaddeus J. Wadas
Publikováno v:
Molecules, Vol 25, Iss 16, p 3672 (2020)
Glioblastoma multiforme (GBM) is the most aggressive glioma of the primary central nervous system. Due to the lack of effective treatment options, the prognosis for patients remains bleak. Fibroblast activation protein alpha (FAP), a 170 kDa type II
Externí odkaz:
https://doaj.org/article/0ccd82dedc384283a9124199814e1c4a
Autor:
Christopher J. Tichacek, Mikalai M. Budzevich, Thaddeus J. Wadas, David L. Morse, Eduardo G. Moros
Publikováno v:
Molecules, Vol 24, Iss 18, p 3397 (2019)
Using targeted ligands to deliver alpha-emitting radionuclides directly to tumor cells has become a promising therapeutic strategy. To calculate the radiation dose to patients, activities of parent and daughter radionuclides must be measured. Scintil
Externí odkaz:
https://doaj.org/article/31793922f8a24839a3aadae3d2f00f8b
Publikováno v:
Molecules, Vol 23, Iss 3, p 638 (2018)
The interest in zirconium-89 (89Zr) as a positron-emitting radionuclide has grown considerably over the last decade due to its standardized production, long half-life of 78.2 h, favorable decay characteristics for positron emission tomography (PET) i
Externí odkaz:
https://doaj.org/article/2f1a3782e0764629934624fbca63d2fb
Autor:
Diane S. Abou, Patrick Zerkel, James Robben, Mark McLaughlin, Tim Hazlehurst, David Morse, Thaddeus J. Wadas, Darpan N. Pandya, Reiko Oyama, Gregory Gaehle, Michael L. Nickels, Daniel L.J. Thorek
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:355-363
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1112965e9ee3dddcb2b8acfb340c0b
https://doi.org/10.1089/cbr.2022.0010
https://doi.org/10.1089/cbr.2022.0010
Autor:
Narges K. Tafreshi, Haitao Ji, Robert W. Engelman, Jordan N Reff, Zhen Wang, Thaddeus J. Wadas, Alberto Chiappori, Christopher J. Tichacek, David L. Morse, Ghassan El-Haddad, Darpan N. Pandya, Mikalai M. Budzevich, David Boulware, Jonathan R. Strosberg
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:3408-3421
There is significant interest in the development of targeted alpha-particle therapies (TATs) for treatment of solid tumors. The metal chelator-peptide conjugate, DOTA-TATE, loaded with the β-particle emitting radionuclide 177Lu ([177Lu]Lu-DOTA-TATE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c91d6f8d22fa2108b214d602152c043
https://doi.org/10.1007/s00259-021-05315-1
https://doi.org/10.1007/s00259-021-05315-1
Autor:
Carley G. Stewart, Brieanna Hilkin, Nicholas D. Gansemer, Susan A. Walsh, Michael R. Acevado, Vamsidhar Akurathi, Darpan N. Pandya, Alejandro F. Comellas, Thaddeus J. Wadas, David W. Dick, John J. Sunderland, David A. Stoltz, Michael J. Welsh, Mahmoud H. Abou Alaiwa
Publikováno v:
2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d1a5746484290a393557c893baf6e7c
https://doi.org/10.1109/isbi52829.2022.9761605
https://doi.org/10.1109/isbi52829.2022.9761605
Autor:
Cynthia S. Day, Akesh Sinha, Darpan N. Pandya, Jason S. Lewis, Kelly E. Henry, Thaddeus J. Wadas, Yusuf Menda, Thomas R. Dilling, Brandie M. Ehrmann, Nikunj Bhatt, Stephen A. Graves, Veronica L. Nagle
Publikováno v:
Inorganic Chemistry. 59:17473-17487
Over the last three decades, the chemistry of zirconium has facilitated antibody development and the clinical management of disease in the precision medicine era. Scientists have harnessed its reactivity, coordination chemistry, and nuclear chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26a9e81687ced33aeb8f87f549085aa
https://doi.org/10.1021/acs.inorgchem.0c02722
https://doi.org/10.1021/acs.inorgchem.0c02722
Publikováno v:
Molecules, Vol 26, Iss 2162, p 2162 (2021)
Molecules
Molecules
Bone metastasis remains a major cause of death in cancer patients, and current therapies for bone metastatic disease are mainly palliative. Bone metastases arise after cancer cells have colonized the bone and co-opted the normal bone remodeling proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f2eb35bd01b2ba8cfba081e8d9e772
https://www.mdpi.com/1420-3049/26/8/2162
https://www.mdpi.com/1420-3049/26/8/2162