Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Thaddeus G. Golos"'
Autor:
Michelle R. Koenig, Jessica Vazquez, Fernanda B. Leyva Jaimes, Ann M. Mitzey, Aleksandar K. Stanic, Thaddeus G. Golos
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Zika virus (ZIKV) can be vertically transmitted during pregnancy resulting in a range of adverse pregnancy outcomes. The decidua is commonly found to be infected by ZIKV, yet the acute immune response to infection remains understudied in vivo. We hyp
Externí odkaz:
https://doaj.org/article/c4b5f3eabe0549428e38f31a4e5f1833
Autor:
Jessica Vazquez, Mona A. Mohamed, Soma Banerjee, Logan T. Keding, Michelle R. Koenig, Fernanda Leyva-Jaimes, Rachel C. Fisher, Emily M. Bove, Thaddeus G. Golos, Aleksandar K. Stanic
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a5f7f353f08c45b08295d94cbfe9a9e6
Autor:
Jessica Vazquez, Mona A. Mohamed, Soma Banerjee, Logan T. Keding, Michelle R. Koenig, Fernanda Leyva Jaimes, Rachel C. Fisher, Emily M. Bove, Thaddeus G. Golos, Aleksandar K. Stanic
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The decidual immunome is dynamic, dramatically changing its composition across gestation. Early pregnancy is dominated by decidual NK cells, with a shift towards T cells later in pregnancy. However, the degree, timing, and subset-specific nature of l
Externí odkaz:
https://doaj.org/article/85b77f4201b1481598767594c8823783
Autor:
Nicholas P. Krabbe, Elaina Razo, Hunter J. Abraham, Rachel V. Spanton, Yujia Shi, Saswati Bhattacharya, Ellie K. Bohm, Julia C. Pritchard, Andrea M. Weiler, Ann M. Mitzey, Jens C. Eickhoff, Eric Sullivan, John C. Tan, Matthew T. Aliota, Thomas C. Friedrich, David H. O’Connor, Thaddeus G. Golos, Emma L. Mohr
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionZika virus (ZIKV) infection during pregnancy results in a spectrum of birth defects and neurodevelopmental deficits in prenatally exposed infants, with no clear understanding of why some pregnancies are more severely affected. Differentia
Externí odkaz:
https://doaj.org/article/fc3e7c5657814d8791677bf87f7d1787
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Nonhuman primates (NHPs) are well-established basic and translational research models for human immunodeficiency virus (HIV) infections and pathophysiology, hematopoietic stem cell (HSC) transplantation, and assisted reproductive technologie
Externí odkaz:
https://doaj.org/article/e31a5b9cd7574fc99593277ca7ef0841
Autor:
Jason T. Weinfurter, Saritha S. D’Souza, Lea M. Matschke, Sarah Bennett, Laurel E. Kelnhofer-Millevolte, Kran Suknuntha, Akhilesh Kumar, Jennifer Coonen, Christian M. Capitini, Peiman Hematti, Thaddeus G. Golos, Igor I. Slukvin, Matthew R. Reynolds
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Allogeneic hematopoietic stem cell transplants (allo-HSCTs) dramatically reduce HIV reservoirs in antiretroviral therapy (ART) suppressed individuals. However, the mechanism(s) responsible for these post-transplant viral reservoir declines a
Externí odkaz:
https://doaj.org/article/22f7e78e3a994a308f11436196586bc8
Autor:
Lindsey N. Block, Jenna Kropp Schmidt, Nicholas S. Keuler, Megan C. McKeon, Brittany D. Bowman, Gregory J. Wiepz, Thaddeus G. Golos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Zika virus (ZIKV) infection at the maternal–placental interface is associated with adverse pregnancy outcomes including fetal demise and pregnancy loss. To determine how infection impacts placental trophoblasts, we utilized rhesus macaque
Externí odkaz:
https://doaj.org/article/655af951117f40ff939cf220e7760d37
Autor:
Jenna Kropp Schmidt, Yun Hee Kim, Nick Strelchenko, Sarah R. Gierczic, Derek Pavelec, Thaddeus G. Golos, Igor I. Slukvin
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2023)
Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications. Nonhuman primates are physiologically closer to humans than other laboratory anim
Externí odkaz:
https://doaj.org/article/dae482dc7dde49ac885ddd30fd2be360
Autor:
Miranda Li, Alyssa Brokaw, Anna M. Furuta, Brahm Coler, Veronica Obregon-Perko, Ann Chahroudi, Hsuan-Yuan Wang, Sallie R. Permar, Charlotte E. Hotchkiss, Thaddeus G. Golos, Lakshmi Rajagopal, Kristina M. Adams Waldorf
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
A wide array of pathogens has the potential to injure the fetus and induce teratogenesis, the process by which mutations in fetal somatic cells lead to congenital malformations. Rubella virus was the first infectious disease to be linked to congenita
Externí odkaz:
https://doaj.org/article/bd50b4e9958c4588bbfd1e7f48f827c4
Autor:
T. Arthur Chang, Gennadiy I. Bondarenko, Behzad Gerami-Naini, Jessica G. Drenzek, Maureen Durning, Mark A. Garthwaite, Jenna Kropp Schmidt, Thaddeus G. Golos
Publikováno v:
Reproductive Biology and Endocrinology, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background The initiation of primate embryo invasion into the endometrium and the formation of the placenta from trophoblasts, fetal mesenchyme, and vascular components are essential for the establishment of a successful pregnancy. The mecha
Externí odkaz:
https://doaj.org/article/5a4366350d684599a1ec35ba45548fd6