Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thaddeus, Judkins"'
Autor:
Timothy Simmons, Elisha Hughes, Dmitry Pruss, Matthew Kucera, Benjamin Roa, Thaddeus Judkins, Thomas Slavin, Victor Abkevich, Ryan Hoff, Srikanth Jammulapati, Susanne Wagner, Dale Muzzey, Jerry Lanchbury, Alexander Gutin
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100945- (2024)
Externí odkaz:
https://doaj.org/article/2a67aed1d3124d9ab3923d655c8d87fd
Autor:
Debora Mancini-DiNardo, Thaddeus Judkins, John Kidd, Ryan Bernhisel, Courtney Daniels, Krystal Brown, Kirsten Meek, Jonathan Craft, Jayson Holladay, Brian Morris, Benjamin B. Roa
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Background Healthcare providers increasingly use information about pathogenic variants in cancer predisposition genes, including sequence variants and large rearrangements (LRs), in medical management decisions. While sequence variant detect
Externí odkaz:
https://doaj.org/article/b4301df67a684499a99d884ff1499575
Autor:
Elisha Hughes, Ryan Bernhisel, Holly Pederson, Braden Probst, Timothy Simmons, Susanne Wagner, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M. Domchek, Charis Eng, Judy Garber, Monique Gary, Ora K. Gordon, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Funmi Olopade, Joseph Vijai, Jeffrey N. Weitzel, Pat Whitworth, Lamis Yehia, Allison Kurian, Mark Robson, Thomas P. Slavin, Alexander Gutin, Jerry S. Lanchbury
Publikováno v:
Cancer Research. 82:P2-11
Background: Polygenic risk scores (PRS) have been shown to provide genomically informed breast cancer risk assessment in both carriers and non-carriers of predisposing genetic mutations. Risk stratification is further improved by combining a PRS with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef9fee751958f718fc65ce0d7ffe404
https://doi.org/10.1158/1538-7445.sabcs21-p2-11-21
https://doi.org/10.1158/1538-7445.sabcs21-p2-11-21
Autor:
Shannon Gallagher, Jeffrey N. Weitzel, Eric Rosenthal, Placede Tshiaba, Danna F. Grear, Jerry S. Lanchbury, Judy Garber, Susanne Wagner, Benjamin B. Roa, Wade Hedegard, Kathryn Dalton, Mark E. Robson, Johnathan M. Lancaster, Alexander Gutin, Allison W. Kurian, Susan M. Domchek, Elisha Hughes, Thaddeus Judkins, Carol A. Adami, Stephanie Meek
Publikováno v:
JCO Precision Oncology
PURPOSE Screening and prevention decisions for women at increased risk of developing breast cancer depend on genetic and clinical factors to estimate risk and select appropriate interventions. Integration of polygenic risk into clinical breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15506d868302a81e4677729c34097bda
https://doi.org/10.1200/po.20.00246
https://doi.org/10.1200/po.20.00246
Autor:
Elisha Hughes, Susanne Wagner, Dmitry Pruss, Ryan Bernhisel, Braden Probst, Victor Abkevich, Timothy Simmons, Brooke Hullinger, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M. Domchek, Charis Eng, Judy Garber, Monique Gary, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Olufunmilayo I. Olopade, Joseph Vijai, Jeffrey N. Weitzel, Pat Whitworth, Lamis Yehia, Ora Gordon, Holly Pederson, Allison Kurian, Thomas P. Slavin, Alexander Gutin, Jerry S. Lanchbury
Publikováno v:
JCO Precision Oncology.
PURPOSE Polygenic risk scores (PRSs) for breast cancer (BC) risk stratification have been developed primarily in women of European ancestry. Their application to women of non-European ancestry has lagged because of the lack of a formal approach to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830cc3eccc7aa0eb7314b3b38435beb5
https://doi.org/10.1200/po.22.00084
https://doi.org/10.1200/po.22.00084
Autor:
Shannon Gallagher, Johnathan M. Lancaster, Judy Garber, Jerry S. Lanchbury, Eric Rosenthal, Mark E. Robson, Susan M. Domchek, Alexander Gutin, Allison W. Kurian, Thaddeus Judkins, Benjamin B. Roa, Placede Tshiaba, Susanne Wagner, Jeffrey N. Weitzel, Elisha Hughes
Publikováno v:
JCO Precision Oncology
PURPOSE Women with a family history of breast cancer are frequently referred for hereditary cancer genetic testing, yet < 10% are found to have pathogenic variants in known breast cancer susceptibility genes. Large-scale genotyping studies have ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7428d8fcf1f5bfdc1d235a03752346ea
https://doi.org/10.1200/po.19.00360
https://doi.org/10.1200/po.19.00360
Autor:
Maria Elias, Debora Mancini-DiNardo, Benoît Leclair, Bradford Coffee, Karla R. Bowles, Benjamin B. Roa, Yaping Qian, Hannah C. Cox, Thaddeus Judkins, Nanda Singh
Publikováno v:
Future Oncology. 15:65-79
Expanded genetic test utilization to guide cancer management has driven the development of larger gene panels and greater diversity in the patient population pursuing testing, resulting in increased identification of atypical or technically challengi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8aa48db725a3181ddef9c414c22963
https://doi.org/10.2217/fon-2018-0476
https://doi.org/10.2217/fon-2018-0476
Autor:
Susanne Wagner, Richard J. Wenstrup, Eric Rosenthal, Alexander Gutin, Jerry S. Lanchbury, Thaddeus Judkins, Elisha Hughes
Publikováno v:
Cancer Research. 78:PD1-08
Background: Unaffected women with a strong family history of breast cancer (BC) are often referred for hereditary cancer testing with multi-gene panels; however, typically Methods: This IRB-approved study includes women of European ancestry tested wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3adbb812939e21041a482a66ca598363
https://doi.org/10.1158/1538-7445.sabcs17-pd1-08
https://doi.org/10.1158/1538-7445.sabcs17-pd1-08
Autor:
Karla R. Bowles, Hannah C. Cox, Maria Elias, Krystal Brown, Benjamin B. Roa, Courtney Daniels, Debora Mancini-DiNardo, Thaddeus Judkins, Yaping Qian, Bradford Coffee, Nanda Singh, Jayson Holladay
Publikováno v:
Cancer Genetics. :159-169
Cancer risks have been previously reported for some retrotransposon element (RE) insertions; however, detection of these insertions is technically challenging and very few oncogenic RE insertions have been reported. Here we evaluate RE insertions ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1978a832f3e55cd54d9feaa04a3121
https://doi.org/10.1016/j.cancergen.2017.08.002
https://doi.org/10.1016/j.cancergen.2017.08.002
Autor:
Jonathan Craft, Courtney Daniels, Krystal Brown, Ryan Bernhisel, John Kidd, Debora Mancini-DiNardo, Benjamin B. Roa, Brian Morris, Kirsten Meek, Thaddeus Judkins, Jayson Holladay
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-9 (2019)
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-9 (2019)
Background Healthcare providers increasingly use information about pathogenic variants in cancer predisposition genes, including sequence variants and large rearrangements (LRs), in medical management decisions. While sequence variant detection is ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f96da6aa3e9ebc60e96de319d6e4f1
https://pubmed.ncbi.nlm.nih.gov/31623605
https://pubmed.ncbi.nlm.nih.gov/31623605