Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Thad A Howard"'
Autor:
Grace Ndeezi, MBChB PhD, Charles Kiyaga, MSc MPhil, Arielle G Hernandez, BA, Deogratias Munube, MBChB, Thad A Howard, MS, Isaac Ssewanyana, MSc, Jesca Nsungwa, MBChB PhD, Sarah Kiguli, MBChB, Christopher M Ndugwa, MBChB, Dr. Russell E Ware, MD PhD, Jane R Aceng, MBChB MPH
Publikováno v:
The Lancet Global Health, Vol 4, Iss 3, Pp e195-e200 (2016)
Background: Sickle cell disease contributes substantially to mortality in children younger than 5 years in sub-Saharan Africa. In Uganda, 20 000 babies per year are thought to be born with sickle cell disease, but accurate data are not available. We
Externí odkaz:
https://doaj.org/article/a2fd245eac9a488a9a816aa064f2be9f
Autor:
Beverly A Schaefer, Jonathan M Flanagan, Ofelia A Alvarez, Stephen C Nelson, Banu Aygun, Kerri A Nottage, Alex George, Carla W Roberts, Connie M Piccone, Thad A Howard, Barry R Davis, Russell E Ware
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164364 (2016)
Discovery and validation of genetic variants that influence disease severity in children with sickle cell anemia (SCA) could lead to early identification of high-risk patients, better screening strategies, and intervention with targeted and preventiv
Externí odkaz:
https://doaj.org/article/f7ba0935a92c4de69929dbb63e87b5f5
Autor:
Vivien A Sheehan, Jacy R Crosby, Aniko Sabo, Nicole A Mortier, Thad A Howard, Donna M Muzny, Shannon Dugan-Perez, Banu Aygun, Kerri A Nottage, Eric Boerwinkle, Richard A Gibbs, Russell E Ware, Jonathan M Flanagan
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110740 (2014)
Hydroxyurea has proven efficacy in children and adults with sickle cell anemia (SCA), but with considerable inter-individual variability in the amount of fetal hemoglobin (HbF) produced. Sibling and twin studies indicate that some of that drug respon
Externí odkaz:
https://doaj.org/article/92b9698c6a9b4d21be5ddfd8aef760dd
Autor:
Arielle G. Hernandez, Charles Kiyaga, Thad A. Howard, Isaac Ssewanyana, Grace Ndeezi, Jane R. Aceng, Russell E. Ware
Publikováno v:
African Journal of Laboratory Medicine, Vol 10, Iss 1, Pp e1-e8 (2021)
Background: Sickle cell anaemia is a common global life-threatening haematological disorder. Most affected births occur in sub-Saharan Africa where children usually go undiagnosed and die early in life. Uganda’s national sickle cell screening progr
Externí odkaz:
https://doaj.org/article/b1c8135242d6442dacd76ae9dc927413
Autor:
Luke R. Smart, Emmanuela E. Ambrose, Georgina Balyorugulu, Primrose Songoro, Idd Shabani, Protas Komba, Mwesige Charles, Thad A. Howard, Kathryn E. McElhinney, Sara M. O’Hara, Jodie Odame, Maria Nakafeero, Janet Adams, Susan E. Stuber, Adam Lane, Teresa S. Latham, Abel N. Makubi, Russell E. Ware
Publikováno v:
Acta Haematologica. 146:95-105
Introduction: Stroke is a severe complication of sickle cell anemia (SCA), with devastating sequelae. Transcranial Doppler (TCD) ultrasonography predicts stroke risk, but implementing TCD screening with suitable treatment for primary stroke preventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dea3456e453ce26008443e5d56a4594
https://doi.org/10.1159/000526322
https://doi.org/10.1159/000526322
Autor:
Emmanuela E. Ambrose, Luke R. Smart, Adolfine Hokororo, Mwesige Charles, Medard Beyanga, Arielle G. Hernandez, Thad A. Howard, Russell E. Ware
Publikováno v:
Blood Advances, Vol 1, Iss , Pp 26-28 (2017)
Externí odkaz:
https://doaj.org/article/d499c4ca25ba4274865d13723b11d919
Autor:
Beverly A. Schaefer, Charles Kiyaga, Thad A. Howard, Grace Ndeezi, Arielle G. Hernandez, Isaac Ssewanyana, Mary C. Paniagua, Christopher M. Ndugwa, Jane R. Aceng, Russell E. Ware
Publikováno v:
Blood Advances, Vol 1, Iss 1, Pp 93-100 (2016)
Abstract: The Uganda Sickle Surveillance Study analyzed dried blood spots that were collected from almost 100 000 infants and young children from all 10 regions and 112 districts in the Republic of Uganda, with the primary objective of determining th
Externí odkaz:
https://doaj.org/article/ed7d5f164393452eb99ae7e4f3f5c875
Autor:
Peter Olupot-Olupot, George Tomlinson, Thomas N. Williams, Léon Tshilolo, Brígida Santos, Luke R. Smart, Kathryn McElhinney, Thad A. Howard, Banu Aygun, Susan E. Stuber, Adam Lane, Teresa S. Latham, Russell E. Ware
Publikováno v:
Blood.
Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) provides hydroxyurea at maximum tolerated dose (MTD) for children with sickle cell anemia (SCA) in sub-Saharan Africa. Beyond reducing SCA-related clinical events, docume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5114c5896e01909f4f86eb51c6edf232
https://pubmed.ncbi.nlm.nih.gov/36375125
https://pubmed.ncbi.nlm.nih.gov/36375125
Autor:
Luke R. Smart, Amanda Pfeiffer, Marina Perez-Plazola, Wilbur A. Lam, Russell E. Ware, Patrick T. McGann, Thad A. Howard, Erika A. Tyburski
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
BMC Medicine
BMC Medicine
Background Severe anemia is common and frequently fatal for hospitalized patients in limited-resource settings. Lack of access to low-cost, accurate, and rapid diagnosis of anemia impedes the delivery of life-saving care and appropriate use of the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e17e5274fac0aafd4d74406d82be06
http://link.springer.com/article/10.1186/s12916-020-01793-6
http://link.springer.com/article/10.1186/s12916-020-01793-6
Autor:
Anu Marahatta, Maisam Abu-El-Haija, Lori Luchtman-Jones, Alexander A. Boucher, Jaimie D. Nathan, Russell E. Ware, Alexander A. Vinks, Thad A. Howard, Min Dong
Publikováno v:
The Journal of Clinical Pharmacology. 61:547-554
Total pancreatectomy with islet autotransplantation is a complex surgical approach for acute recurrent or chronic pancreatitis that frequently triggers extreme thrombocytosis (platelets ≥ 1000 × 109 /L). Thrombocytosis can be prothrombotic, so cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faaf23c6b8cc47b75c54e307e07abd41
https://doi.org/10.1002/jcph.1759
https://doi.org/10.1002/jcph.1759