Výsledky vyhledávání - "Thaís Meira Menezes"

Binding Mechanism between Acetylcholinesterase and Drugs Pazopanib and Lapatinib: Biochemical and Biophysical Studies

Autor: Wilka Karla Martins do Vale, Regildo M. G. Martins, Jorge L. Neves, Thaís Meira Menezes, Gustavo M. Seabra, Roberto Carlos Silva dos Santos, Ranilson de Souza Bezerra, Chenglong Li, Caio Rodrigo Dias de Assis, Alcides Jairon Lacerda Cintra

Publikováno v: ACS Chemical Neuroscience. 12:4500-4511

Tyrosine kinase inhibitors (TKIs) are antitumor compounds that prevent the phosphorylation of proteins in a biological environment. However, the multitarget performance of TKIs promotes them as possible candidates for drug repositioning. In this work

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0959887c451644ad7ebfe35f2dee0c44
https://doi.org/10.1021/acschemneuro.1c00521

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A new lectin from the floral capitula of Egletes viscosa (EgviL): Biochemical and biophysical characterization and cytotoxicity to human cancer cells

Autor: Jorge L. Neves, Marília Cavalcanti Coriolano, Teresinha Gonçalves da Silva, Thiago Henrique Napoleão, Thaís Meira Menezes, Marcela Rodrigues Barros, Dayane Correia Gomes, Maria Tereza dos Santos Correia, Patrícia Maria Guedes Paiva

Publikováno v: International Journal of Biological Macromolecules. 168:676-685

Egletes viscosa is a plant with therapeutic value due to its antibacterial, antinociceptive and gastroprotective properties. This study aimed to purify, characterize, and evaluate the cytotoxicity of a lectin (EgviL) from the floral capitula of E. vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7f3fc65476cfebd53443a6fa592531
https://doi.org/10.1016/j.ijbiomac.2020.11.124

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Probing the toxic interactions between the reactive dye Drimaren Red and Human Serum Albumin

Autor: Marcos Gomes Ghislandi, Priscila Gubert, Antonio Marinho da Silva Neto, Thaís Meira Menezes, Caio Rodrigo Dias de Assis, Jorge L. Neves

Azo dyes like Drimaren Red CL-5B (DR, CI Reactive Red 241) represent a class of compounds extensively used in the textile industry and are extremely dangerous to the environment and human health. Therefore, understanding the binding characteristics b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e29b192cc701ec9d7e06fd22508122e
https://doi.org/10.1101/2021.07.17.452798

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Furan inhibitory activity against tyrosinase and impact on B16F10 cell toxicity

Autor: Marcela Rodrigues Barros, Gustavo M. Seabra, Dartagnam Sá Pires, Thaís Meira Menezes, Jefferson L. Princival, Lucas Pereira da Silva, Jorge L. Neves

Publikováno v: International Journal of Biological Macromolecules. 136:1034-1041

Many skin disorders and diseases are related to tyrosinase activity, in particular, due to the vital role played by this enzyme in the melanogenic process. Although numerous natural and synthetic tyrosinase inhibitors have been published, substantial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4585ce481a2673ab2b29aa273cc4500
https://doi.org/10.1016/j.ijbiomac.2019.06.120

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Efficient tyrosinase nano-inhibitor based on carbon dots behaving as a gathering of hydrophobic cores and key chemical group

Autor: Marcela Rodrigues Barros, Yarima Sanchez Garcia, Lucas Pereira da Silva, Thaís Meira Menezes, Jorge L. Neves

Publikováno v: Colloids and surfaces. B, Biointerfaces. 207

Small organic molecules have been extensively applied to achieve enzymatic inhibition. Although numerous efforts have been made to deliver efficient inhibitors, small inhibitors applications are hindered by many drawbacks. Moreover, reporters compris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e877280acff3260a00a2656b1bfa4c9f
https://pubmed.ncbi.nlm.nih.gov/34343910

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Impact on cholinesterase-inhibition and in silico investigations of sesquiterpenoids from Amazonian Siparuna guianensis Aubl

Autor: Gustavo M. Seabra, Wanderli Pedro Tadei, Regildo M. G. Martins, Marcela Rodrigues Barros, Ranilson de Souza Bezerra, Antonio Alves de Melho Filho, Francisco H. Xavier-Júnior, Ana Cristina Goncalves Reis De Melo, Caio Rodrigo Dias de Assis, Thaís Meira Menezes, Vany Perpetua Ferraz, Jorge L. Neves, Gilvan Takeshi Yogui, Bruno Oliveira de Veras

Publikováno v: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 252

The plant popularly known as "negramina" (Siparuna guianensis Aubl.), member of the family Siparunaceae produces an essential oil that presents several biological activities reported in literature. Here, the essential oil was obtained by hydrodistill

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1363964dc05eba3b3389fae98bd84c
https://pubmed.ncbi.nlm.nih.gov/33561686

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Evaluation of europium-based carbon nanocomposites as bioimaging probes: Preparation, NMR relaxivities, binding effects over plasma proteins and cytotoxic aspects

Autor: Gustavo Tavares Ventura, Rafaela Muniz de Queiroz, Yarima Sanchez Garcia, Wagner B. Dias, Jorge L. Neves, Adriane R. Todeschini, Thaís Meira Menezes, Caio Rodrigo Dias de Assis

Publikováno v: Colloids and Surfaces A: Physicochemical and Engineering Aspects. 628:127250

It is highly desirable to develop water-dispersible lanthanide-based luminescent probes with facile preparation, great bioavailability, and excellent photo properties for biomedical applications. Numerous carbon photoactive nanostructures (from diver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f2cc09ec2abeeae4727bfb20e33e974
https://doi.org/10.1016/j.colsurfa.2021.127250

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