Výsledky vyhledávání - "Thaís Doeler, Algarve"

Akademický článek

Efeitos da cisplatina em cobaias: histologia coclear e genotoxidade Cisplatin effects on guinea pigs: cochlear histology and genotoxicity

Autor: Cacineli Marion de Franceschi, Tania Tochetto, Aron Ferreira da Silveira, Mara Rejane Fantinel, Thaís Doeler Algarve

Publikováno v: Brazilian Journal of Otorhinolaryngology, Vol 77, Iss 6, Pp 728-735 (2011)

Conhecer as respostas do DNA aos agentes externos como a cisplatina pode ser relevante para o diagnóstico e tratamento das alterações auditivas causadas pela administração deste fármaco. OBJETIVOS: Verificar a influência da cisplatina sobre a

Externí odkaz: https://doaj.org/article/dab7e62946aa428887c4f724af487c4e

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Akademický článek

Autor: Fernanda Barbisan, Jéssica de Rosso Motta, Alexis Trott, Verônica Azzolin, Eduardo Bortoluzzi Dornelles, Matheus Marcon, Thaís Doeler Algarve, Marta Maria Medeiros Frescura Duarte, Clarice Pinheiro Mostardeiro, Taís Cristina Unfer, Karen Lilian Schott, Ivana Beatrice Mânica da Cruz

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e107299 (2014)

Methotrexate (MTX) is a folic acid antagonist used in high doses as an anti-cancer treatment and in low doses for the treatment of some autoimmune diseases. MTX use has been linked to oxidative imbalance, which may cause multi-organ toxicities that c

Externí odkaz: https://doaj.org/article/f7deef1ead724fd5bf198925c6714032

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Parental and preimaginal exposure to methylmercury disrupts locomotor activity and circadian rhythm of adult Drosophila melanogaster

Autor: Charles Elias Assmann, Toshiro Aigaki, Ivana Beatrice Mânica da Cruz, Thaís Doeler Algarve

Methylmercury (MeHg) is a well-known toxic pollutant. However, little is known about the effects of this toxic agent in an adult as a consequence of a parental or preimaginal exposure. This study used Drosophila melanogaster to investigate whether a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a9995aa0bc5b96000ac723df6d50f2

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DNA damage and postural balance in multiple sclerosis patients

Autor: Ivana Beatrice Mânica da Cruz, Aron Ferreira da Silveira, Fábio Saraiva Flôres, Thaís Doeler Algarve, Fernando Copetti, Karla Mendonça Menezes

Publikováno v: Fisioterapia em Movimento v.30 suppl.1 2017
Fisioterapia em Movimento
Pontifícia Universidade Católica do Paraná (PUC-PR)
instacron:PUC_PR
Fisioterapia em Movimento, Vol 30, Iss suppl 1, Pp 85-91
CIÊNCIAVITAE
Fisioterapia em Movimento, Volume: 30 Supplement 1, Pages: 85-91, Published: 2017

Introduction: Multiple Sclerosis (MS) is a chronic inflammatory disease characterized by infiltration of inflammatory cells on the Central Nervous System (CNS). There is evidence that cumulative DNA damage can contribute to various mechanisms underly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d35b39eb55b9daae2367f7ee75ffb74
https://doi.org/10.1590/1980-5918.030.s01.ao08

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Parental and preimaginal exposure to methylmercury disrupts locomotor activity and circadian rhythm of adult

Autor: Thaís Doeler, Algarve, Charles Elias, Assmann, Toshiro, Aigaki, Ivana Beatrice Mânica, da Cruz

Publikováno v: Drug and chemical toxicology. 43(3)

Methylmercury (MeHg) is a well-known toxic pollutant. However, little is known about the effects of this toxic agent in an adult as a consequence of a parental or preimaginal exposure. This study used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc83d61458863c8b27b8ecfca20c973f
https://pubmed.ncbi.nlm.nih.gov/30033776

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Apoptotic markers and DNA damage are related to late phase of stroke: Involvement of dyslipidemia and inflammation

Autor: Ana Lucia Cervi Prado, Eduardo Tanuri Pascotini, Ariane Ethur Flores, Marta Maria Medeiros Frescura Duarte, Luiz Fernando Freire Royes, Guilherme Vargas Bochi, Thaís Doeler Algarve, Aline Kegler, Ivana Beatrice Mânica da Cruz, Rafael Noal Moresco, Michele Rechia Fighera, Patricia Gabbi

Publikováno v: Physiology & Behavior. 151:369-378

Oxidative stress and brain inflammation are thought to contribute to the pathophysiology of cerebral injury in acute stroke, leading to apoptosis and cell death. Lipid accumulation may lead to progression of carotid plaques and inflammation, contribu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262512eb7d4de0bb6f1ed99638be2405
https://doi.org/10.1016/j.physbeh.2015.08.005

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Genomodifier capacity assay: a non-cell test using dsDNA molecules to evaluate the genotoxic/genoprotective properties of chemical compounds

Autor: Eliza Ribas da Silveira Flôres, Francine Carla Cadoná, Ivana Beatrice Mânica da Cruz, Maria Fernanda Manica-Cattani, Alencar Machado, Charles Elias Assmann, Raul Moreira Oliveira, Thaís Doeler Algarve

Publikováno v: Anal. Methods. 6:8559-8568

We describe here an ultrasensitive and fast protocol called a GEMO assay (genomodifier capacity assay). This non-cell method was developed to identify chemicals with genomodifier (genotoxic and/or genoprotective) capacity. The assay is performed in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca896238a81a3cf10336b1eeee04fc9f
https://doi.org/10.1039/c4ay01709a

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Association between Machado–Joseph disease and oxidative stress biomarkers

Autor: Caroline Belló, Ivana Beatrice Mânica da Cruz, Laura Segabinazzi Pacheco, Adriano Flesch Lenz, Aron Ferreira da Silveira, Maria Fernanda Mânica-Cattani, Thaís Doeler Algarve, Lucien J. Houenou, Alexis Trott

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 757:99-103

Spinocerebellar ataxia type 3, also called Machado-Joseph disease (MJD), is an hereditary autosomal dominant neurodegenerative disease that affects the cerebellum and its afferent and efferent connections. Since the mechanism by which mutant ataxin-3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9280fb548782ccdc8c547bedf1734e
https://doi.org/10.1016/j.mrgentox.2013.06.023

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The protective effects of guaraná extract (Paullinia cupana) on fibroblast NIH-3T3 cells exposed to sodium nitroprusside

Autor: Ivana Beatrice Mânica da Cruz, Margareth Linde Athayde, Daniel Rodrigo Marinowic, G.F.F. Dos Santos, Michel Mansur Machado, Euler Esteves Ribeiro, Félix Alexandre Antunes Soares, Thaís Doeler Algarve, Denise Cantarelli Machado, Fernanda Barbisan, L.S. Bittencourt

Publikováno v: Food and Chemical Toxicology. 53:119-125

The antioxidant effects of the hydro-alcoholic guaraná extract (Paullinia cupana var. sorbilis Mart.) on nitric oxide (NO) and other compounds generated from the degradation of sodium nitroprusside (SNP) in an embryonic fibroblast culture (NIH-3T3 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa6104f869b95c15eb473456068cf62

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Influence of Val16Ala SOD2 polymorphism on the in-vitro effect of clomiphene citrate in oxidative metabolism

Autor: Felipe D'Almeida Costa, Ivana Beatrice Mânica da Cruz, Olmiro Cezimbra de Souza Filho, Luiz Filipe Machado Garcia, Thaís Doeler Algarve, Michele Rorato Sagrillo, Maria Fernanda Mânica-Cattani, Eduardo Bortoluzzi Dornelles

Publikováno v: Reproductive BioMedicine Online. 24:474-481

This study investigated the in-vitro antioxidant properties of the ovulation induction drug, clomiphene citrate, and assessed whether its effects are influenced by the Val16Ala polymorphism in the SOD2 gene, which encodes manganese superoxide dismuta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99212e3eb137a1e1d77c18cb0a8398ab
https://doi.org/10.1016/j.rbmo.2012.01.009

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