Zobrazeno 1 - 10
of 1 612
pro vyhledávání: '"Th17 Cell"'
Autor:
A. S. Elgouhari, N. M. Lazareva, O. P. Baranova, I. V. Kudryavtsev, T. P. Ses, M. M. Ilkovich, A. A. Totolian
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 755-764 (2024)
Sarcoidosis is a multisystem inflammatory disease of unknown etiology characterized by the formation of non-caseating granulomas, most commonly in the lung tissue. It presents with two main forms: acute and chronic. Patients with chronic sarcoidosis
Externí odkaz:
https://doaj.org/article/4a4142217ee4473ca71ccb48220ff35b
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract The T-helper 17 (Th17) cell and regulatory T cell (Treg) axis plays a crucial role in the development of multiple sclerosis (MS), which is regarded as an immune imbalance between pro-inflammatory cytokines and the maintenance of immune toler
Externí odkaz:
https://doaj.org/article/3fd917ebe4e54ed78b1ebadeb6a55db9
Autor:
Yuanyuan An, Ruoyu Zhao, Wang Liu, Chenxi Wei, Luxin Jin, Mingzhu Zhang, Xiaobin Ren, Hongbing He
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 496-505 (2024)
Background: Quercetin (QU) plays an important role in treating periodontitis; however, the mechanism through which microRNAs regulate Th17 cell differentiation has not been determined. Methods: QU was administered intragastrically to periodontitis ra
Externí odkaz:
https://doaj.org/article/5d8ab68c48644715857e329d3da3ce4b
Autor:
Ling Chen, Yanru Xiang, Shirong Zhong, Yinglin Wu, Jiaqi Liu, Yan Wu, Zhizhi Wang, Guodong Huang
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 10, Pp 1276-1283 (2024)
Objective(s): Ulcerative colitis (UC) is a commonly recurrent inflammatory bowel disease. T helper 17 (Th17)/regulatory T (Treg) cell balance plays an essential role in UC progression. However, it is unknown whether curcumin chitosan microspheres (CC
Externí odkaz:
https://doaj.org/article/076e5e8e91ee49c9a0e8b1ab32221275
Autor:
Lanjiao Li, Jichun Chen, Zhenyan Wang, Yan Xu, Hao Yao, Wulong Lei, Xiyuan Zhou, Minming Zheng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThis study examined the impact of 5’-(N- ethylcarboxamido)adenosine (NECA) in the peripheral blood of healthy individuals, those with diabetes mellitus, diabetic retinopathy (DR), and C57BL/6 mice, both in vivo and in vitro.MethodsEnzym
Externí odkaz:
https://doaj.org/article/1a6a9a72bd0646e69e15df914eab2b18
Publikováno v:
Open Life Sciences, Vol 18, Iss 1, Pp 1233-40 (2023)
Rheumatoid arthritis (RA) is a chronic autoimmune disorder. Its pathogenesis is complicated but highly related to aberrant Th17 overactivation. Uncontrolled Th17 cell expansion and activation in populations and associated activities contribute to the
Externí odkaz:
https://doaj.org/article/0098f619613840bbb635288189a01f49
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 8, Pp 1322-1325 (2023)
Chronic obstructive pulmonary disease (COPD) is a chronic and progressive respiratory disease. Transcription factor T-bet is involved in the inflammatory response and lung function changes of COPD, which is expected to become a new target for the pre
Externí odkaz:
https://doaj.org/article/b65a953d576d47cd89b9b353d4883545
Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 2521-2533 (2023)
Gai Ge,1 Jingzhe Shang,2,3 Tian Gan,1 Zhiming Chen,1 Chun Pan,1 Youming Mei,1 Siyu Long,4 Aiping Wu,2,3 Hongsheng Wang1,5,6 1Laboratory of Mycobacteria, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, N
Externí odkaz:
https://doaj.org/article/d46d6bcd77144defa52facc40f870ec2
Autor:
Li-Li Wu, Xiao-Yan Li, Kai Deng, Bing-Liang Lin, Hong Deng, Dong-Ying Xie, Geng-Lin Zhang, Qi-Yi Zhao, Zhi-Shuo Mo, Yue-Hua Huang, Zhi-Liang Gao
Publikováno v:
Liver Research, Vol 7, Iss 2, Pp 136-144 (2023)
Background and aims: The primary goal of chronic hepatitis B (CHB) treatment is to reduce hepatitis B surface antigen (HBsAg). T helper 17 (Th17) and regulatory T (Treg) cells are essential for the development of CHB. However, how Th17 and Treg cells
Externí odkaz:
https://doaj.org/article/8d959db95e01445fb794174860636754
Autor:
N. M. Lazareva, I. V. Kudryavtsev, O. P. Baranova, D. V. Isakov, M. K. Serebriakova, A. A. Bazhanov, N. A. Arsentieva, N. E. Liubimova, T. P. Ses’, M. M. Ilkovich, A. A. Totolian
Publikováno v:
Медицинская иммунология, Vol 25, Iss 5, Pp 1049-1058 (2023)
Immune cell hyperactivation along with cytokines they overproduce plays an important role in sarcoidosis and related disease pathogenesis. A central place in the immunopathogenesis of sarcoidosis is held by diverse cell-mediated reactions governed by
Externí odkaz:
https://doaj.org/article/262bf29d573e44e2aef43c438dac5fa2