Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Th1/Th2 polarization"'
Targeting MELK improves PD-1 blockade efficiency in cervical cancer via enhancing antitumor immunity
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200759- (2024)
The balance between T helper 1 (Th1) and T helper 2 (Th2) has a critical function in determining intratumoral immune response and anti-PD-1 immunotherapy. The level of maternal embryonic leucine zipper kinase (MELK) is reported to correlate with infi
Externí odkaz:
https://doaj.org/article/58b9d55876ae4e8a91bb87c348d0946c
Autor:
Carina Chan-Song Münch, Bishnu Prashad Upadhaya, Binod Rayamajhee, Anurag Adhikari, Manuel Münch, Nora En-Nosse, Katharina Kowalski, Markus Eickmann, Christian Bauer, Krishna Das Manandhar, Christian Keller
Publikováno v:
International Journal of Infectious Diseases, Vol 128, Iss , Pp 78-87 (2023)
Objectives: Scrub typhus is an emerging infectious disease in Asia caused by Orientia tsutsugamushi (Ot). From Nepal, only scant data on the genetic epidemiology of this agent is available, and determinants of immunoregulation are poorly understood.
Externí odkaz:
https://doaj.org/article/e34a8c948cb8470ca821fb39bd1d679f
Autor:
Xiaomin Wang, Shuiqin Li, Yongcan Wu, Demei Huang, Caixia Pei, Yilan Wang, Shihua Shi, Fei Wang, Zhenxing Wang
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Long-term exposure to high concentrations of PM2.5 may cause immune system dysfunction and damage to the respiratory and cardiovascular systems. PM2.5 may cause CD4 + T helper cells to polarize toward TH1 or TH2 cell types, which
Externí odkaz:
https://doaj.org/article/2e83e44389a74ec1b5e519a8eba6b6a2
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Chao Li, Bo Yan, Jinkai Sun, Huiying Zhuang, Weijia Gu, Yiping Lu, Bo Liu, Dong Weng, Jie Chen, Ying Chen, Fangwei Liu
Publikováno v:
Frontiers in Immunology
Silicosis is characterized by chronic lung inflammation and fibrosis, which are extremely harmful to human health. The pathogenesis of silicosis involves uncontrolled immune processes. Evidence supports that regulatory B cells (Bregs) produce negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ab0d70b543a0750f2f7e8e96b94b0
https://doi.org/10.3389/fimmu.2017.00110
https://doi.org/10.3389/fimmu.2017.00110
Autor:
Amidou K Atchamou, Marcellin K Amoussou-Guenou, Magloire Pandoua Nekoua, Kabirou Moutairou, Daniel Amoussou-Guenou, Odilon Nouatin, Akadiri Yessoufou, Rufine Fachinan
Publikováno v:
African Health Sciences; Vol 16, No 3 (2016); 712-724
Background: The role of the immune system in insulin resistance associated with type 2 diabetes has been suggested. Objectives : We assessed the profile of Th1/Th2 cytokines along with the frequencies of immune cells in insulin-treated type 2 diabeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f91fc67b45688aaf998e755422742c
https://www.ajol.info/index.php/ahs/article/view/146021
https://www.ajol.info/index.php/ahs/article/view/146021
Publikováno v:
International Journal of Biomedical Science : IJBS
The exogenous cytokine milieu can influence Th1/Th2 polarization. Besides the differential functional properties, T lymphocytes also acquire distinct profiles of chemokine receptors. Human Th1 lymphocytes preferentially express CCR5 and CXCR3 while T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71f1b3d6b37060b840a9eb54d24694d8
http://europepmc.org/articles/PMC3614579
http://europepmc.org/articles/PMC3614579
Autor:
Richard K. Grencis, John J. Worthington, Alisa Gruden-Movsesijan, Ljiljana Sofronic-Milosavljevic, Mark A. Travis, Natasa Ilic
Publikováno v:
Parasite Immunology
Many parasitic helminth infections induce Th2-type immune responses and engage the regulatory network. In this study, we specifically investigated the influence of antigens derived from different life stages of the helminth Trichinella spiralis on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3443efc9d16db268b2d4684413bdbc75
https://pubmed.ncbi.nlm.nih.gov/21793858
https://pubmed.ncbi.nlm.nih.gov/21793858