Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

Autor: Wei-Yu Lin, Camp, Nicola J., Ghoussaini, Maya, Beesley, Jonathan, Michailidou, Kyriaki, Hopper, John L., Apicella, Carmel, Southey, Melissa C., Stone, Jennifer, Schmidt, Marjanka K., Broeks, Annegien, Van’t Veer, Laura J., Th. Rutgers, Emiel J., Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter A., Haeberle, Lothar, Ekici, Arif B.

Publikováno v: Human Molecular Genetics; Jan2015, Vol. 24 Issue 1, p285-298, 14p, 4 Diagrams, 1 Graph

Correspondence

Autor: de Bree, Eelco, van Ruth, Serge, Th. Rutgers, Emiel J., Zoetmulder, Frans A.N.

Publikováno v: European Journal of Surgical Oncology; September 2002, Vol. 28 Issue: 6 p685-686, 2p

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Autor: Ghoussaini M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Edwards SL; 1] Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia [2] School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Nord S; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Cowper-Sal Lari R; The Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5T 2M9., Desai K; 1] The Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5T 2M9 [2] Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, USA., Kar S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Hillman KM; 1] Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia [2] School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia., Kaufmann S; 1] Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia [2] School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia., Glubb DM; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Beesley J; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Dicks E; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Guo Q; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Schmidt MK; Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, 1066 CX Amsterdam, The Netherlands., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Luben R; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Brown J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-17177, Sweden., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-17177, Sweden., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-17177, Sweden., Klevebring D; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-17177, Sweden., Bojesen SE; 1] Copenhagen General Population Study, Herlev Hospital, 2730 Herlev, Copenhagen, Denmark [2] Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Copenhagen, Denmark [3] Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Nordestgaard BG; 1] Copenhagen General Population Study, Herlev Hospital, 2730 Herlev, Copenhagen, Denmark [2] Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Copenhagen, Denmark [3] Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Nielsen SF; 1] Copenhagen General Population Study, Herlev Hospital, 2730 Herlev, Copenhagen, Denmark [2] Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Copenhagen, Denmark., Flyger H; Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Copenhagen, Denmark., Lambrechts D; 1] Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000 Leuven, Belgium [2] Vesalius Research Center (VRC), VIB, 3000 Leuven, Belgium., Thienpont B; 1] Vesalius Research Center (VRC), VIB, 3000 Leuven, Belgium [2] Vesalius Research Center, University of Leuven, 3000 Leuven, Belgium., Neven P; 1] Department of Oncology, University of Leuven, 3000 Leuven, Belgium [2] Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals Leuven, 3000 Leuven, Belgium., Wildiers H; 1] Department of Oncology, University of Leuven, 3000 Leuven, Belgium [2] Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals Leuven, 3000 Leuven, Belgium., Broeks A; Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, 1066 CX Amsterdam, The Netherlands., Van't Veer LJ; Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, 1066 CX Amsterdam, The Netherlands., Th Rutgers EJ; Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, 1066 CX Amsterdam, The Netherlands., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Vachon C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Flesch-Janys D; Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, 20246 Hamburg, Germany., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Gibson L; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, FI-00029 HUS, Finland., Muranen TA; Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, FI-00029 HUS, Finland., Aittomäki K; Department of Clinical Genetics, University of Helsinki, Helsinki University Central Hospital, Helsinki, FI-00029 HUS, Finland., Blomqvist C; Department of Oncology, University of Helsinki, Helsinki University Central Hospital, Helsinki, FI-00029 HUS, Finland., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-17177, Sweden., Li J; Human Genetics Division, Genome Institute of Singapore, Singapore 138672, Singapore., Liu J; Human Genetics Division, Genome Institute of Singapore, Singapore 138672, Singapore., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-17177, Sweden., Kang D; 1] Cancer Research Institute, Seoul National University College of Medicine, Seoul 110-799, Korea [2] Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 151-742, Korea [3] Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea., Choi JY; 1] Cancer Research Institute, Seoul National University College of Medicine, Seoul 110-799, Korea [2] Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 151-742, Korea., Park SK; 1] Cancer Research Institute, Seoul National University College of Medicine, Seoul 110-799, Korea [2] Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 151-742, Korea [3] Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea., Noh DY; Department of Surgery, Seoul National University College of Medicine, Seoul 110-799, Korea., Matsuo K; Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences, Fukuoka 812-8582, Japan., Ito H; Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi 464-8681, Japan., Iwata H; Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya 484-8681, Japan., Yatabe Y; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya 484-8681, Japan., Guénel P; 1] Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 94807 Villejuif, France [2] University Paris-Sud, UMRS 1018, 94807 Villejuif, France., Truong T; 1] Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 94807 Villejuif, France [2] University Paris-Sud, UMRS 1018, 94807 Villejuif, France., Menegaux F; 1] Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 94807 Villejuif, France [2] University Paris-Sud, UMRS 1018, 94807 Villejuif, France., Sanchez M; 1] Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 94807 Villejuif, France [2] University Paris-Sud, UMRS 1018, 94807 Villejuif, France., Burwinkel B; 1] Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany [2] Molecular Epidemiology Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Marme F; 1] Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany [2] National Center for Tumor Diseases, University of Heidelberg, 69120 Heidelberg, Germany., Schneeweiss A; 1] Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany [2] National Center for Tumor Diseases, University of Heidelberg, 69120 Heidelberg, Germany., Sohn C; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA., Tseng CC; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA., Van Den Berg D; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA., Stram DO; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA., Benitez J; 1] Centro de Investigación en Red de Enfermedades Raras (CIBERER), 46010 Valencia, Spain [2] Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Zamora MP; Servicio de Oncología Médica, Hospital Universitario La Paz, 28046 Madrid, Spain., Perez JI; Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, 33012 Oviedo, Spain., Menéndez P; Servicio de Anatomía Patológica, Hospital Monte Naranco, 33013 Oviedo, Spain., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Lu W; Shanghai Center for Disease Control and Prevention, Shanghai 200336, China., Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, China., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Cox A; CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield S10 2RX, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Reed MW; CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield S10 2RX, UK., Andrulis IL; 1] Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5 [2] Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8., Knight JA; 1] Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada M5T 3M7 [2] Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Glendon G; Ontario Cancer Genetics Network, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Tchatchou S; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Sawyer EJ; Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's &St Thomas' NHS Foundation Trust in partnership with King's College London, London SE1 9RT, UK., Tomlinson I; Wellcome Trust Centre for Human Genetics, Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7BN, UK., Kerin MJ; Clinical Science Institute, University Hospital Galway, Galway, Ireland., Miller N; Clinical Science Institute, University Hospital Galway, Galway, Ireland., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Henderson BE; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Schumacher F; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Le Marchand L; Epidemiology Program, Cancer Research Center, University of Hawaii, Honolulu, Hawaii 96813, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm SE-17177, Sweden., Margolin S; Department of Oncology-Pathology, Karolinska Institutet, Stockholm SE-17177, Sweden., Teo SH; 1] Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre, 59100 Kuala Lumpur, Malaysia [2] Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya 47500 Selangor, Malaysia., Yip CH; Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre, 59100 Kuala Lumpur, Malaysia., Lee DS; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya 47500 Selangor, Malaysia., Wong TY; Singapore Eye Research Institute, National University of Singapore, Singapore 168751, Singapore., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, 3008 AE Rotterdam, The Netherlands., Martens JW; Department of Medical Oncology, Erasmus MC Cancer Institute, 3008 AE Rotterdam, The Netherlands., Collée JM; Department of Clinical Genetics, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands., van Deurzen CH; Department of Pathology, Erasmus University Medical Center, 3075 EA Rotterdam, The Netherlands., Hopper JL; Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, Melbourne School of Population Health, University of Melbourne, Melbourne, Victoria 3010, Australia., Southey MC; Department of Pathology, The University of Melbourne, Melbourne, Victoria 3010, Australia., Tsimiklis H; Department of Pathology, The University of Melbourne, Melbourne, Victoria 3010, Australia., Kapuscinski MK; Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, Melbourne School of Population Health, University of Melbourne, Melbourne, Victoria 3010, Australia., Shen CY; 1] College of Public Health, China Medical University, Taichung 40402, Taiwan, China [2] Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, China., Wu PE; Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, China., Yu JC; Department of Surgery, Tri-Service General Hospital, Taipei 114, Taiwan, China., Chen ST; Department of Surgery, Changhua Christian Hospital, Changhua City 500, Taiwan, China., Alnæs GG; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Borresen-Dale AL; 1] Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway [2] Institute of Clinical Medicine, University of Oslo (UiO), 0318 Oslo, Norway., Giles GG; 1] Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia [2] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Milne RL; 1] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia [2] Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria 3053, Australia., McLean C; Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria 3004, Australia., Muir K; 1] Division of Health Sciences, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK [2] Institute of Population Health, University of Manchester, Manchester M13 9PL, UK., Lophatananon A; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK., Stewart-Brown S; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK., Siriwanarangsan P; Ministry of Public Health, Bangkok 10400, Thailand., Hartman M; 1] Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore [2] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore., Miao H; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore., Buhari SA; Division of General Surgery, National University Health System, Singapore 117597, Singapore., Teo YY; 1] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore [2] Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546, Singapore., Fasching PA; 1] Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA [2] Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Haeberle L; Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany., Beckmann MW; Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Brenner H; 1] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany [2] German Cancer Consortium (DKTK), 69120 Heidelberg, Germany., Dieffenbach AK; 1] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany [2] German Cancer Consortium (DKTK), 69120 Heidelberg, Germany., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Stegmaier C; Saarland Cancer Registry, 66119 Saarbrücken, Germany., Swerdlow A; 1] Division of Breast Cancer Research, Institute of Cancer Research, London SM2 5NG, UK [2] Division of Genetics and Epidemiology, Institute of Cancer Research, London SM2 5NG, UK., Ashworth A; Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK., Orr N; Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK., Schoemaker MJ; Division of Genetics and Epidemiology, Institute of Cancer Research, London SM2 5NG, UK., García-Closas M; 1] Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK [2] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Lissowska J; Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, 02-781 Warsaw, Poland., Simard J; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Quebec, Canada G1V 4G2., Goldberg MS; 1] Department of Medicine, McGill University, Montreal, Quebec, Canada H3G 2M1 [2] Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada H3A 1A8., Labrèche F; Département de médecine sociale et préventive, Département de santé environnementale et santé au travail, Université de Montréal, Montreal, Quebec, Canada H3T 1A8., Dumont M; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Quebec, Canada G1V 4G2., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, NordLab Oulu/Oulu University Hospital, University of Oulu, FI-90220 Oulu, Finland., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, NordLab Oulu/Oulu University Hospital, University of Oulu, FI-90220 Oulu, Finland., Jukkola-Vuorinen A; Department of Oncology, Oulu University Hospital, University of Oulu, FI-90220 Oulu, Finland., Brauch H; 1] Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany [2] University of Tübingen, 72074 Tübingen, Germany [3] German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), 44789 Bochum, Germany., Koto YD; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, 53113 Bonn, Germany., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy., Peterlongo P; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 20139 Milan, Italy., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia (IEO), 20141 Milan, Italy., Volorio S; 1] IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 20139 Milan, Italy [2] Cogentech Cancer Genetic Test Laboratory, 20133 Milan, Italy., Dörk T; Department of Obstetrics and Gynaecology, Hannover Medical School, 30625 Hannover, Germany., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, 30625 Hannover, Germany., Helbig S; Department of Obstetrics and Gynaecology, Hannover Medical School, 30625 Hannover, Germany., Mannermaa A; 1] Cancer Center of Eastern Finland, University of Eastern Finland, FI-70211 Kuopio, Finland [2] Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, FI-70210 Kuopio, Finland [3] School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, FI-70211 Kuopio, Finland., Kataja V; 1] Cancer Center of Eastern Finland, University of Eastern Finland, FI-70211 Kuopio, Finland [2] School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, FI-70211 Kuopio, Finland., Kosma VM; 1] Cancer Center of Eastern Finland, University of Eastern Finland, FI-70211 Kuopio, Finland [2] Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, FI-70210 Kuopio, Finland [3] School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, FI-70211 Kuopio, Finland., Hartikainen JM; 1] Cancer Center of Eastern Finland, University of Eastern Finland, FI-70211 Kuopio, Finland [2] Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, FI-70210 Kuopio, Finland [3] School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, FI-70211 Kuopio, Finland., Devilee P; Department of Human Genetics &Department of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Tollenaar RA; Department of Surgical Oncology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Seynaeve C; Family Cancer Clinic, Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Centre, 3075 EA Rotterdam, The Netherlands., Van Asperen CJ; Department of Clinical Genetics, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, 70-115 Szczecin, Poland., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, 70-115 Szczecin, Poland., Jaworska-Bieniek K; Department of Genetics and Pathology, Pomeranian Medical University, 70-115 Szczecin, Poland., Durda K; Department of Genetics and Pathology, Pomeranian Medical University, 70-115 Szczecin, Poland., Slager S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Toland AE; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA., Ambrosone CB; Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Yannoukakos D; Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens 15310, Greece., Sangrajrang S; National Cancer Institute, Bangkok 10400, Thailand., Gaborieau V; International Agency for Research on Cancer, Lyon, Cedex 08, France., Brennan P; International Agency for Research on Cancer, Lyon, Cedex 08, France., McKay J; International Agency for Research on Cancer, Lyon, Cedex 08, France., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Torres D; 1] Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany [2] Institute of Human Genetics, Pontificia University Javeriana, Bogota, DC 11001000, Colombia., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Anton-Culver H; Department of Epidemiology, University of California Irvine, Irvine, California 92697, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 92697, USA., Luccarini C; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Baynes C; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Ahmed S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Maranian M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Healey CS; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., González-Neira A; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Pita G; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Alonso MR; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Alvarez N; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Herrero D; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Tessier DC; Centre d'innovation Génome Québec et Université McGill, Montréal, Quebec, Canada H3A OG1., Vincent D; McGill University, Montreal, Quebec, Canada H3A OG1., Bacot F; McGill University, Montreal, Quebec, Canada H3A OG1., de Santiago I; Cancer Research UK, Cambridge Institute, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK., Carroll J; Cancer Research UK, Cambridge Institute, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK., Caldas C; Cancer Research UK, Cambridge Institute, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK., Brown MA; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia., Lupien M; 1] The Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5T 2M9 [2] Ontario Cancer Genetics Network, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5 [3] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 1L7., Kristensen VN; 1] Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway [2] Institute of Clinical Medicine, University of Oslo (UiO), 0318 Oslo, Norway [3] Department of Clinical Molecular Biology (EpiGen), University of Oslo (UiO), 0450 Oslo, Norway., Pharoah PD; 1] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK [2] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Chenevix-Trench G; 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Publikováno v: Nature communications [Nat Commun] 2014 Sep 23; Vol. 4, pp. 4999. Date of Electronic Publication: 2014 Sep 23.