Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Thérèse Rachell THEODORO"'
Autor:
Mariana Fatima Muaccad Gama Wagner, Thérèse Rachell Theodoro, Carlos D’. Apparecida Santos Machado Filho, Luiza Keiko Matsuka Oyafuso, Maria Aparecida Silva Pinhal
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Psoriasis is a chronic inflammatory disease dependent upon a complex interaction between genetic predisposition and immunological factors. It is characterized by skin lesions throughout the body, causing great morbidity and affect
Externí odkaz:
https://doaj.org/article/63bd6b8090844e029c9f690260124e7c
Autor:
Jussara Celi Conceição Oliveira, Marcelo Luis Steiner, Thérèse Rachell Theodoro, Ana Maria Amaral Antonio Mader, Giuliana Petri, Luiz Carlos Abreu, Maria Aparecida da Silva Pinhal, César Eduardo Fernandes, Luciano Melo Pompei
Publikováno v:
Revista Brasileira de Ginecologia e Obstetrícia, Vol 41, Iss 12, Pp 703-709 (2020)
Abstract Objective To investigate the action of testosterone (T), isolated or associated with estradiol benzoate (EB), on the proliferation markers and apoptosis of breasts of ovariectomized rats. Methods A total of 48 castrated female Wistar rats we
Externí odkaz:
https://doaj.org/article/0142b0101a494a17884ddd87b6e1245a
Autor:
Olavo Magalhães PICANÇO-JUNIOR, Thérèse Rachell THEODORO, Paulo José de Brito Silva ALBUQUERQUE, Rodrigo Nascimento PINHEIRO, Jaques WAISBERG
Publikováno v:
ABCD: Arquivos Brasileiros de Cirurgia Digestiva, Vol 34, Iss 4 (2022)
RESUMO - INTRODUÇÃO: O papilomavírus humano (HPV) é agente das doenças sexualmente transmissíveis de maior prevalência no mundo que estão associadas ao câncer do colo do útero e canal anal. A ação do HPV na carcinogênese colorretal não
Externí odkaz:
https://doaj.org/article/8e2a9d2e0c51410a9c769385a9693914
Autor:
Marcelo Luis Steiner, Thérèse Rachell Theodoro, Shirley Gimenez Garcia, Ana Maria Amaral Antonio Mader, Luciano de Melo Pompei, Maria Aparecida da Silva Pinhal, César Eduardo Fernandes
Publikováno v:
Revista Brasileira de Ginecologia e Obstetrícia, Vol 41, Iss 7, Pp 449-453 (2019)
Abstract Objective To analyze the effects of estrogen alone or in combination with progestogens and tibolone (TIB) on the expression of the extracellular matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9), of perlecan, and of heparanase (HPSE) of th
Externí odkaz:
https://doaj.org/article/adba7ee2ceff4f32ae22bce1e4010ed0
Autor:
Thérèse Rachell Theodoro, Leandro Luongo Matos, Renan Pelluzzi Cavalheiro, Giselle Zenker Justo, Helena Bonciani Nader, Maria Aparecida Silva Pinhal
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Heparanase (HPSE) is an endo-beta-glucuronidase that degrades heparan sulfate (HS) chains on proteoglycans. The oligosaccharides generated by HPSE promote angiogenesis, tumor growth and metastasis. Heparanase-2 (HPSE2), a close ho
Externí odkaz:
https://doaj.org/article/214510b927d14efeaa7722520cb9c61c
Autor:
Demétrius Eduardo Germini, Maria Isete Fares Franco, Fernando Luiz Affonso Fonseca, Flávia de Sousa Gehrke, Beatriz da Costa Aguiar Alves Reis, Leonardo Cardili, Celina Tizuko Fujiyama Oshima, Thérèse Rachell Theodoro, Jaques Waisberg
Publikováno v:
Tumor Biology, Vol 41 (2019)
Inflammation is an important etiological factor of colorectal carcinoma and may be related to colorectal carcinoma growth and proliferation. This study aimed to verify whether the presence of chronic inflammation represented by tumor necrosis factor-
Externí odkaz:
https://doaj.org/article/9e84c2b3f19a4860b6c6864a86da60aa
Autor:
Maria Aparecida Silva Pinhal, Maria Carolina Leal Almeida, Alessandra Scorse Costa, Thérèse Rachell Theodoro, Rodrigo Lorenzetti Serrano, Carlos D'Apparecida Santos Machado Filho
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 91, Iss 5, Pp 595-600 (2016)
Abstract: Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer. Objectiv
Externí odkaz:
https://doaj.org/article/957c7d45f19c4e14a6f98f83a0ca33dc
Autor:
Luciano Miller Reis Rodrigues, Thérèse Rachell Theodoro, Leandro Luongo Matos, Ana Maria Mader, Carlo Milani, Maria Aparecida da Silva Pinhal
Publikováno v:
Clinics, Vol 66, Iss 5, Pp 903-909 (2011)
OBJECTIVE: To determine the molecules involved in extracellular matrix remodeling and to identify and quantify heparanase isoforms present in herniated and degenerative discs. INTRODUCTION: Heparanase is an endo-beta-glucuronidase that specifically a
Externí odkaz:
https://doaj.org/article/30c04d6cd2af4fb5b28b2967715c5d35
Autor:
Leandro Luongo Matos, Eloah Rabello Suarez, Thérèse Rachell Theodoro, Damila Cristina Trufelli, Carina Mucciolo Melo, Larissa Ferraz Garcia, Olivia Capela Grimaldi Oliveira, Maria Graciela Luongo Matos, Jossi Ledo Kanda, Helena Bonciani Nader, João Roberto Maciel Martins, Maria Aparecida Silva Pinhal
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141139 (2015)
The search for a specific marker that could help to distinguish between differentiated thyroid carcinoma and benign lesions remains elusive in clinical practice. Heparanase (HPSE) is an endo-beta-glucoronidase implicated in the process of tumor invas
Externí odkaz:
https://doaj.org/article/ac960fdc2c8b40029d33c9cd13e8771c
Autor:
Carina Mucciolo Melo, Clarice Silvia Taemi Origassa, Thérèse Rachell Theodoro, Leandro Luongo Matos, Thaís Aguilar Miranda, Camila Melo Accardo, Rodrigo Ippolito Bouças, Eloah Rabello Suarez, Madalena Maria Nunes Silva Pares, Daniel Reis Waisberg, Giovanna Canato Toloi, Helena Bonciani Nader, Jaques Waisberg, Maria Aparecida Silva Pinhal
Publikováno v:
São Paulo Medical Journal, Vol 133, Iss 1, Pp 28-35
CONTEXT AND OBJECTIVE: Heparanase-1 degrades heparan sulfate and has been correlated with tumor progression. Although the isoform heparanase-2 has no catalytic activity, it seems to be important for modulating heparanase-1 activity. Cathepsin B is a
Externí odkaz:
https://doaj.org/article/25df9f0126ac4d3b9b3b1fed3b7a0e9f