Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Thérèse, Di Paolo"'
Autor:
Andrée-Anne Poirier, Mélissa Côté, Mélanie Bourque, Hend Jarras, Jérôme Lamontagne-Proulx, Marc Morissette, Thérèse Di Paolo, Denis Soulet
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 85-97 (2022)
Beneficial effects of estrogens have been reported in Parkinson's disease (PD) for many years. We previously reported their neuroprotective and anti-inflammatory potentials in the enteric nervous system of the intestine, a region possibly affected du
Externí odkaz:
https://doaj.org/article/42678706da1f4cc79ae2a3852d6de6c3
Autor:
Jérôme Lamontagne-Proulx, Katherine Coulombe, Marc Morissette, Marie Rieux, Frédéric Calon, Thérèse Di Paolo, Denis Soulet
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 977 (2023)
The mutation and overexpression of the alpha-synuclein protein (αSyn), described as synucleinopathy, is associated with Parkinson’s disease (PD)-like pathologies. A higher prevalence of PD is documented for men versus women, suggesting female horm
Externí odkaz:
https://doaj.org/article/7ea8f5137db44e9aa8654669441934b8
Autor:
Andrée-Anne Poirier, Mélissa Côté, Hend Jarras, Nadhir Litim, Jérôme Lamontagne-Proulx, Sara Al-Sweidi, Marc Morissette, Asmaa Lachhab, Martin Pelletier, Thérèse Di Paolo, Denis Soulet
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gastrointestinal disorders in Parkinson’s disease (PD) have been associated with neuronal alteration in the plexus of the gut. We previously demonstrated the immunomodulatory effect of female hormones to treat enteric neurodegeneration in the 1-met
Externí odkaz:
https://doaj.org/article/c8da65148103495c9b9e6e7073e55f5d
Autor:
Amandine Isenbrandt, Katherine Coulombe, Marc Morissette, Mélanie Bourque, Jérôme Lamontagne-Proulx, Thérèse Di Paolo, Denis Soulet
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 152 (2023)
Parkinson’s disease (PD) is characterized by neurodegeneration and neuroinflammation. PD prevalence and incidence are higher in men than in women and modulation of gonadal hormones could have an impact on the disease course. This was investigated i
Externí odkaz:
https://doaj.org/article/e137716e59c640dcb28b3c3760448afa
Autor:
Mélanie Bourque, Laurent Grégoire, Waseema Patel, David Dickens, Ralph Snodgrass, Thérèse Di Paolo
Publikováno v:
Cells, Vol 11, Iss 22, p 3530 (2022)
N-methyl-D-aspartate (NMDA) receptors have been implicated in L-Dopa-induced dyskinesias (LID) in Parkinson’s disease patients, but the use of antagonists that directly inhibit this receptor is associated with severe side effects. L-4-chlorokynuren
Externí odkaz:
https://doaj.org/article/8b37e3a260b24c82ac20b147191915c7
Publikováno v:
Cells, Vol 11, Iss 4, p 691 (2022)
Proinflammatory markers were found in brains of Parkinson’s disease (PD) patients. After years of L-Dopa symptomatic treatment, most PD patients develop dyskinesias. The relationship between inflammation and L-Dopa-induced dyskinesias (LID) is stil
Externí odkaz:
https://doaj.org/article/902966ee8fb34a12b105cea489c46598
Autor:
Soulet, Jérôme Lamontagne-Proulx, Katherine Coulombe, Marc Morissette, Marie Rieux, Frédéric Calon, Thérèse Di Paolo, Denis
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 977
The mutation and overexpression of the alpha-synuclein protein (αSyn), described as synucleinopathy, is associated with Parkinson’s disease (PD)-like pathologies. A higher prevalence of PD is documented for men versus women, suggesting female horm
Publikováno v:
Neurobiology of Disease, Vol 95, Iss , Pp 46-53 (2016)
The most abundant interneurons in the primate striatum are those expressing the calcium-binding protein calretinin (CR). The present immunohistochemical study provides detailed assessments of their morphological traits, number, and topographical dist
Externí odkaz:
https://doaj.org/article/75fe0ddd9e724468941e09e170187f2d
Publikováno v:
Androgens
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. A greater prevalence and incidence of PD are reported in men than in women, suggesting a potential contribution of sex, genetic difference and/or
Autor:
Cynthia Lecours, Maude Bordeleau, Léo Cantin, Martin Parent, Thérèse Di Paolo, Marie-Ève Tremblay
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Microglia, often described as the brain-resident macrophages, play crucial roles in central nervous system development, maintenance, plasticity, and adaptation to the environment. Both aging and chronic stress promote microglial morphological and fun
Externí odkaz:
https://doaj.org/article/f3c5250e74e44f43b8290ad67c2f7602