Novel point-of-care cytokine biomarker lateral flow test for the screening for sexually transmitted infections and bacterial vaginosis: study protocol of a multicentre multidisciplinary prospective observational clinical study to evaluate the performance and feasibility of the Genital InFlammation Test (GIFT)

Autor: Suzanna C Francis, Tania Crucitti, Lindi Masson, Emma Michele Harding-Esch, Sarah Bernays, Chido Dziva Chikwari, Katharina Kranzer, Tsitsi Bandason, Karen Webb, Katherine Gill, Tanya Pidwell, David Anderson, Nicola Thomas, Janneke H H M van de Wijgert, Ayako Honda, Aina Harimanana, Elise Smith, Edina Sinanovic, Constance R S Mackworth-Young, Mutsawashe Chisenga, Eneyi Kpokiri, Linda Gail Bekker, Bich-Tram Huynh, Dimitri Rasoloson‎‎, Fezile Khumalo, Micaela Lurie, Phumla Radebe, Bahiah Meyer, Lyndon Mungur, Ashley Uys, Darryl Uys, Monalisa Manhanzva, Tinashe Mwaturura, Camille Fortas, Karabo Mahlangu, Rindra Vatosoa Randremanana, Stephanie Ramboarina, Théodora Mayouya Gamana, Reziky Mangahasimbola, Fatime Ramla Tanko, Jo-Anne Passmore, Conita Lombard, Celia Mehou-Loko, Yacoeb Ganief, Rezeen Daniels, Anda Madikida, Joseph F Chipanga, Patricia Makunyire, Felicia Mhangami, Jayjay Karumazondo, Jason Naidoo, Saberi Marias, Solange Rasoanandrianina, Dimitri Ravoavison, Patrick Andry Rakotonirina, Andrilaina Razakarivony, Hantamalala Randria, Alphonsine Rahantarimalala, Lala Rafetrarivony, Barivola Bernardson, Tsiry Rasolofomanana, Norohasina Randriamange, Antsanirina Nomenjanahary, Laurah Rabarisoa, Sahara Raveloson, Laura Randrianantenaina, Hanitratiavina Rakotonindriana, Fenosoa Voanarivolalao, Vaomalala Ranarinandra, Farai Machinga

Publikováno v: BMJ Open, Vol 14, Iss 5 (2024)

Introduction A prototype lateral flow device detecting cytokine biomarkers interleukin (IL)-1α and IL-1β has been developed as a point-of-care test—called the Genital InFlammation Test (GIFT)—for detecting genital inflammation associated with s

Externí odkaz: https://doaj.org/article/0421f938b62244ed961a065cf19e60ec

The impact of COVID-19 on clinical research for Neglected Tropical Diseases (NTDs): A case study of bubonic plague.

Autor: Tsinjo Fehizoro Rasoanaivo, Josephine Bourner, Ravaka Niaina Randriamparany, Théodora Mayouya Gamana, Voahangy Andrianaivoarimanana, Mily Harijaona Raherivelo, Harivelo Randriamampionona, Minoarisoa Rajerison, Mihaja Raberahona, Alex Paddy Salam, Tansy Edwards, Piero L Olliaro, Rindra Vatosoa Randremanana

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0010064 (2021)

BackgroundAmong the many collaterals of the COVID-19 pandemic is the disruption of health services and vital clinical research. COVID-19 has magnified the challenges faced in research and threatens to slow research for urgently needed therapeutics fo

Externí odkaz: https://doaj.org/article/40fa664e3e2f4b6bb66f96cdfbb5568f

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial—an update to the published protocol

Autor: Randremanana, Rindra Vatosoa¹ (AUTHOR), Raberahona, Mihaja^2,3 (AUTHOR), de Dieu Randria, Mamy Jean^3,4 (AUTHOR), Bourner, Josephine⁵ (AUTHOR) josephine.bourner@ndm.ox.ac.uk, Zadonirina, Gabriella¹ (AUTHOR), Razananaivo, Hanitra¹ (AUTHOR), Mayouya-Gamana, Théodora¹ (AUTHOR), Mangahasimbola, Reziky¹ (AUTHOR), Pesonel, Elise⁵ (AUTHOR), Gillesen, Annelies⁵ (AUTHOR), Rajerison, Minoarisoa¹ (AUTHOR), Andrianaivoarimanana, Voahangy¹ (AUTHOR), Edwards, Tansy⁶ (AUTHOR), Horby, Peter⁵ (AUTHOR), Olliaro, Piero⁵ (AUTHOR)

Publikováno v: Trials. 7/5/2024, Vol. 25 Issue 1, p1-3. 3p.

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus streptomycin + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial.

Autor: Randremanana, Rindra Vatosoa¹ (AUTHOR), Raberahona, Mihaja² (AUTHOR), Randria, Mamy Jean de Dieu³ (AUTHOR), Rajerison, Minoarisoa¹ (AUTHOR), Andrianaivoarimanana, Voahangy¹ (AUTHOR), Legrand, Agathe¹ (AUTHOR), Rasoanaivo, Tsinjo Fehizoro¹ (AUTHOR), Randriamparany, Ravaka¹ (AUTHOR), Mayouya-Gamana, Théodora¹ (AUTHOR), Mangahasimbola, Reziky¹ (AUTHOR), Bourner, Josie⁴ (AUTHOR) josephine.bourner@ndm.ox.ac.uk, Salam, Alex⁴ (AUTHOR), Gillesen, Annelies⁴ (AUTHOR), Edwards, Tansy⁵ (AUTHOR), Schoenhals, Matthieu¹ (AUTHOR), Baril, Laurence¹ (AUTHOR), Horby, Peter⁴ (AUTHOR), Olliaro, Piero⁴ (AUTHOR)

Publikováno v: Trials. 8/17/2020, Vol. 21 Issue 1, pN.PAG-N.PAG. 1p. 7 Charts.