Zobrazeno 1 - 10
of 606
pro vyhledávání: '"Tgfbr1"'
Gga-miRNA-181-5p family facilitates chicken myogenesis via targeting TGFBR1 to block TGF-β signaling
Autor:
Xiaoxu Shen, Yongtong Tian, Wentao He, Can He, Shunshun Han, Yao Han, Lu Xia, Bo Tan, Menggen Ma, Houyang Kang, Jie Yu, Qing Zhu, Huadong Yin
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 8, Pp 2764-2777 (2024)
MicroRNAs (miRNAs) have been demonstrated to control chicken skeletal muscle growth, however, the potential function of the miR-181-5p family in chicken myogenesis remains largely unknown. Here, our study identified the two chicken (Gallus gallus; Gg
Externí odkaz:
https://doaj.org/article/b851fa1a2f324ddd904cc77e033e1b75
Autor:
Chen Huang, Wenwen Zhang
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-4 (2024)
Abstract Background We described a case of abdominal aortic aneurysm complicated by type B thoracic aortic dissection, in whom molecular analysis revealed a pathogenic TGFBR1 missense mutation. Case presentation A 36-year-old woman was admitted to ou
Externí odkaz:
https://doaj.org/article/34ecda01c6034da993c81497d3df266a
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Idiopathic pulmonary fibrosis (IPF) is a progressive and life-threatening respiratory disease characterized by worsening lung function due to excessive scarring. The objective of this study was to investigate the role of the long non-coding RNA ANRIL
Externí odkaz:
https://doaj.org/article/8bafc272c8fa42928bbbc62e71806cb1
Autor:
Huiqi Tan, Mia Xinfang Miao, Rylee Xu Luo, Joan So, Lei Peng, Xiaoxuan Zhu, Eva Hin Wa Leung, Lina Zhu, Kui Ming Chan, Martin Cheung, Siu Yuen Chan
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Nucleosome assembly proteins (NAPs) have been identified as histone chaperons. Testis‐Specific Protein, Y‐Encoded‐Like (TSPYL) is a newly arisen NAP family in mammals. TSPYL2 can be transcriptionally induced by DNA damage and TGFβ cau
Externí odkaz:
https://doaj.org/article/5b11482ae15f4614abc925667ecbfef7
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100441- (2024)
Chronic non-healing wounds impose a significant economic burden on the healthcare system. Among the existing strategies in wound healing therapy, targeting specific enzymes, namely tyrosyl-tRNA synthetase, TGFBR1, IL-1β, and Pseudomonas aeruginosa M
Externí odkaz:
https://doaj.org/article/6b371c743fe24a5da7adde1121b7e991
Autor:
Honglin Xu, Haifeng Miao, Guanghong Chen, Guoyong Zhang, Yue Hua, Yuting Wu, Tong Xu, Xin Han, Changlei Hu, Mingjie Pang, Leyi Tan, Bin Liu, Yingchun Zhou
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 6, Pp 743-754 (2023)
Background: Myocardial fibrosis post-myocardial infarction (MI) can induce maladaptive cardiac remodeling as well as heart failure. Although 20(S)-ginsenoside Rg3 (Rg3) has been applied to cardiovascular diseases, its efficacy and specific molecular
Externí odkaz:
https://doaj.org/article/2d095b0b7ded4fb4947a4837673c52e4
Autor:
Mingting Wu, Zhenyan Wang, Xiaoqian Shi, Danni Zan, Hong Chen, Shuqiao Yang, Fangping Ding, Liu Yang, Pingping Tan, Runlin Z. Ma, Jing Wang, Lishuang Ma, Yingmin Ma, Jiawei Jin
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Background Idiopathic pulmonary fibrosis (IPF) bears high mortality due to unclear pathogenesis and limited therapeutic options. Therefore, identifying novel regulators is required to develop alternative therapeutic strategies. Methods The l
Externí odkaz:
https://doaj.org/article/6783bca8af394f65b4d47655f75cd68f
Autor:
Linyuan Shen, Tianci Liao, Qiuyang Chen, Yuhang Lei, Linghui Wang, Hao Gu, Yanhao Qiu, Ting Zheng, Yiting Yang, Chenggang Wei, Lei Chen, Ye Zhao, Lili Niu, Shunhua Zhang, Yan Zhu, Mingzhou Li, Jinyong Wang, Xuewei Li, Mailin Gan, Li Zhu
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 1033-1045 (2023)
Abstract Background Increasing evidence shows that tRNA‐derived small RNAs (tsRNAs) are not only by‐products of transfer RNAs, but they participate in numerous cellular metabolic processes. However, the role of tsRNAs in skeletal muscle regenerat
Externí odkaz:
https://doaj.org/article/c70cd53ed1434c439948650350ec36fc
Publikováno v:
Autoimmunity, Vol 56, Iss 1 (2023)
Circular RNAs (circRNAs) are functional molecules in all kinds of fibrosis diseases. The current study was performed for the exploration of circ_0007535 in pulmonary fibrosis. RNA levels for circ_0007535, miR-18a-5p, and transforming growth factor-β
Externí odkaz:
https://doaj.org/article/0f856e76831b470cb608126643d6b44e
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