Zobrazeno 1 - 10
of 10 642
pro vyhledávání: '"Tgf-β1"'
Publikováno v:
Cell Adhesion & Migration, Vol 18, Iss 1, Pp 1-11 (2024)
We aimed to investigate galectin-1 overexpression induces normal fibroblasts (NFs) translates into cancer-associated fibroblasts (CAFs). Galectin-1 overexpression was conducted in Human embryonic lung fibroblasts (HFL1) cell. The motilities of H1299
Externí odkaz:
https://doaj.org/article/45bd411b7a7e47d5995a37643de20f3f
Autor:
Hangcheng Guo, Zujian Hu, Xuejia Yang, Ziwei Yuan, Mengsi Wang, Chaoyue Chen, Lili Xie, Yuanyuan Gao, Wangjian Li, Yongheng Bai, Chunjing Lin
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1189-1200 (2024)
Pancreatic cancer (PC) is an aggressive and metastatic gastrointestinal tumor with a poor prognosis. Persistent activation of the TGF-β/Smad signaling induces PC cell (PCC) invasion and infiltration via epithelial-to-mesenchymal transition (EMT). He
Externí odkaz:
https://doaj.org/article/d9af0ac656924a8a9c44b7a043c4c60d
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Ischemic stroke is a type of stroke in which blood vessel blockage prevents blood supply to the brain. Transforming growth factor beta 1 (TGF-β1) is involved in the pathophysiology of several inflammatory diseases, including ischemic stroke
Externí odkaz:
https://doaj.org/article/9bb9fa836aa34dfd9f723f486163283a
Autor:
Pengfei Gao, Yanjiao Lu, Kun Tang, Wei Wang, Tongsheng Wang, Yingwei Zhu, Jianping Zhao, Yimin Mao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Ficolins were originally identified as proteins that bind to transforming growth factor-β1 (TGF-β1). They are capable of activating the complement system through lectin pathway for immune system protection. Ficolin-2 and 3 have
Externí odkaz:
https://doaj.org/article/8a3d8a2992884a85a70b898be6128f52
Autor:
Yufeng Shang, Guopeng Chen, Li Liu, Ruiyang Pan, Xinqi Li, Hui Shen, Yuxin Tan, Linlu Ma, Xiqin Tong, Weida Wang, Xiaoqin Chen, Zhongjun Xia, Xiaoyan Liu, Fuling Zhou
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract At present, the characteristics of double-hit multiple myeloma (DHMM) are unknown. We retrospectively analyzed the clinical data from 433 new diagnosed MM patients and found that DHMM have a higher β2-MG level and percentage of bone marrow
Externí odkaz:
https://doaj.org/article/79c965582c8b4c9da66af54724a3133a
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Repair of the damaged meniscus is a scientific challenge owing to the poor self-healing potential of the white area of the meniscus. Tissue engineering provides a new method for the repair of meniscus injuries. In this study, we explored the
Externí odkaz:
https://doaj.org/article/62bd1f04334541a0bce31166fecdb1bd
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract To assess the level of both pro-inflammatory and anti-inflammatory cytokines in the aqueous humor (AH) of patients suffering from uveitis, with or without coexisting glaucoma, and compare them with patients diagnosed with primary open-angle
Externí odkaz:
https://doaj.org/article/8ad157822e524d08a2d9f20e15d0270e
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract This study explores the role and potential mechanisms of microRNA-125b-5p (miR-125b-5p) in pulmonary fibrosis (PF). PF is a typical outcome of many chronic lung diseases, with poor prognosis and the lack of appropriate medical treatment beca
Externí odkaz:
https://doaj.org/article/911d4cd15e924f7abbabf46d177473b9
Autor:
Rui-Juan Gao, Nigala Aikeremu, Nan Cao, Chong Chen, Ke-Tao Ma, Li Li, Ai-Mei Zhang, Jun-Qiang Si
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Pulmonary arterial hypertension (PAH) is a worldwide challenging disease characterized by progressive elevation of pulmonary artery pressure. The proliferation, migration and phenotypic transformation of pulmonary smooth muscle ce
Externí odkaz:
https://doaj.org/article/3fc2a4ec804946f8a797b6f91518957e
Autor:
Meng Tu, Chunya Lu, Hongxia Jia, Shanshan Chen, Yan Wang, Jing Li, Jiuling Cheng, Ming Yang, Guojun Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease of unknown etiology. Despite the increasing global incidence and poor prognosis, the exact pathogenic mechanisms remain elusive. Currently,
Externí odkaz:
https://doaj.org/article/558af0d06e1d47d9aad5943dc5a82b00