Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tg Park Tae Gwan Park"'
Autor:
Jy Jin Ju-Youn Jin, Sw Seo Soo-Won Seo, Yh Kim Yong-Hyun Kim, Sj Lee Se-Jeong Lee, Kh Bae Ki-Hyun Bae, Tg Park Tae Gwan Park, Km Joo Kyeung-Min Joo, Hk Yang Hee-Kyoung Yang, Dh Nam Do-Hyun Nam, Hi Kim Hye-In Kim
Publikováno v:
Bioconjugate Chemistry. 22:2568-2572
RNA interference is a powerful strategy that inhibits gene expression through specific mRNA degradation. In vivo, however, the application of small interfering RNAs (siRNAs) is severely limited by their instability and their poor delivery into target
Publikováno v:
Bioconjugate Chemistry. 21:289-295
Cationic quantum dots (QDs) were utilized to complex small interfering RNA (siRNA) for studying intracellular trafficking, unpacking, and gene silencing. Positively charged polyethylenimine (PEI) was covalently conjugated on the surface of QDs to com
Autor:
Sd Jo Sung Duk Jo, Js Kim Jee Seon Kim, Wh Kong Won Ho Kong, Kh Bae Ki-Hyun Bae, Tg Park Tae Gwan Park
Publikováno v:
Pharmaceutical research. 29(2)
Cationic lipid-coated gold nanoparticles were developed for efficient intracellular delivery of therapeutic siRNA.Particle formation was characterized by UV-visible spectroscopy, atomic force microscopy, and dynamic light scattering analysis. Cellula
Autor:
Sh Moon Seung-Ho Moon, J-H Lee, Kr Lee Kyu-Ri Lee, Yuhan Lee, Jw Cheon Jin-Woo Cheon, Tg Park Tae Gwan Park
Publikováno v:
Angewandte Chemie (International ed. in English). 48(23)
Cancer-cell-targeted gene silencing was observed with a magnetic-nanoparticle platform (MEIO, magnetism-engineered iron oxide) on which a fluorescent dye, siRNA, and a RGD-peptide targeting moiety were attached (see picture). The different functional
Publikováno v:
Biomacromolecules. 8(2)
PEO-PPO-PEO/PEG shell cross-linked nanocapsules encapsulating an oil phase in their nanoreservoir structure was developed as a target-specific carrier for a water-insoluble drug, paclitaxel. Oil-encapsulating PEO-PPO-PEO/PEG composite nanocapsules we
Publikováno v:
Journal of nanoscience and nanotechnology. 6(9-10)
A polyelectrolyte complex (PEC) micelle-based antisense oligodeoxynucleotide (ODN) delivery system was designed to overcome intrinsic limitations of cationic lipid-mediated gene transfer. Cationic lipid (Lipofectamine™, LF) and ODN conjugated poly(
Publikováno v:
Journal of nanoscience and nanotechnology. 6(9-10)
Dendritic cells (DCs) are professional antigen presenting cells that induce, sustain, and regulate immune responses. Gene modification of DCs is of particular interest for immunotherapy of diseases where the immunes system has failed or is abnormally
Publikováno v:
Journal of Biotechnology. 131:S48-S49
Autor:
Je Kim Ju Eun Kim, Tg Park Tae Gwan Park, Sy Lee Seung Yong Lee, Ch Ahn Cheol-Hee Ahn, Yuhan Lee Lee
Publikováno v:
Journal of Materials Chemistry. 19:8198
A thermogelling PEG-PPG-PEG triblock copolymer, Pluronic F127, was modified with diamines containing different numbers of secondary amino groups in order to produce a novel pH-sensitive gelling material. The degree of end group modification was over