Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells.

Autor: Schmitt L; Institute for Molecular Medicine I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Krings KS; Institute for Molecular Medicine I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Wolsing A; Institute of Biochemistry and Molecular Biology I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Buque X; Department of Physiology, Faculty of Medicine and Nursing, Universidad del País Vasco, Vitoria-gasteiz, Spain., Zimmermann M; Institute of Biochemistry and Molecular Biology I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Flores-Romero H; Institute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Cologne, Germany.; Ikerbasque, Basque Foundation for Science, Bilbao, 48013, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain., Lenz T; Molecular Proteomics Laboratory, Biological-Medical-Research Centre (BMFZ), Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Lechtenberg I; Institute for Molecular Medicine I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Peter C; Institute for Molecular Medicine I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Stork B; Institute for Molecular Medicine I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Teusch N; Institute of Pharmaceutical Biology and Biotechnology, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Proksch P; Institute of Pharmaceutical Biology and Biotechnology, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Stühler K; Molecular Proteomics Laboratory, Biological-Medical-Research Centre (BMFZ), Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., García-Sáez AJ; Institute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Cologne, Germany., Reichert AS; Institute of Biochemistry and Molecular Biology I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany., Aspichueta P; Department of Physiology, Faculty of Medicine and Nursing, Universidad del País Vasco, Vitoria-gasteiz, Spain.; Biobizkia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain., Bhatia S; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, University Hospital Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany., Wesselborg S; Institute for Molecular Medicine I, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany. sebastian.wesselborg@uni-duesseldorf.de.

Publikováno v: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Nov 12; Vol. 22 (1), pp. 541. Date of Electronic Publication: 2024 Nov 12.

Aplospojaveedins A-C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategy.

Autor: Gao Y; Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., Frank M; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., Teusch N; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., Woschko D; Institute of Inorganic and Structural Chemistry, Heinrich Heine University, Düsseldorf, Germany., Janiak C; Institute of Inorganic and Structural Chemistry, Heinrich Heine University, Düsseldorf, Germany., Mándi A; Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary., Kurtán T; Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary., Hartmann R; Institute of Biological Information Processing: Structural Biochemistry (IBI-7), Forschungszentrum Jülich GmbH, Jülich, Germany., Schiedlauske K; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., van Geelen L; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., Kalscheuer R; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., Kaiser J; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Gertzen CGW; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Gohlke H; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.; Institute of Bio- and Geosciences (IBG-4: Bioinformatics), Forschungszentrum Jülich GmbH, Jülich, Germany., Wang BG; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China., Proksch P; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Düsseldorf, Germany., Liu Z; Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2024 Sep 27; Vol. 15, pp. 1458622. Date of Electronic Publication: 2024 Sep 27 (Print Publication: 2024).

The Monocytic Cell Line THP-1 as a Validated and Robust Surrogate Model for Human Dendritic Cells.

Autor: Hölken JM; Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine University Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf, Germany., Teusch N; Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine University Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 11; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 11.

A Novel In Vitro Wound Healing Assay Using Free-Standing, Ultra-Thin PDMS Membranes.

Autor: Uysal K; Institute for Bioengineering, University of Applied Sciences Aachen/Campus Juelich, Heinrich-Mussmannstr. 1, 52428 Jülich, Germany., Firat IS; Institute for Bioengineering, University of Applied Sciences Aachen/Campus Juelich, Heinrich-Mussmannstr. 1, 52428 Jülich, Germany., Creutz T; Institute for Bioengineering, University of Applied Sciences Aachen/Campus Juelich, Heinrich-Mussmannstr. 1, 52428 Jülich, Germany., Aydin IC; Institute for Bioengineering, University of Applied Sciences Aachen/Campus Juelich, Heinrich-Mussmannstr. 1, 52428 Jülich, Germany., Artmann GM; Institute for Bioengineering, University of Applied Sciences Aachen/Campus Juelich, Heinrich-Mussmannstr. 1, 52428 Jülich, Germany., Teusch N; Institute for Pharmaceutical Biology and Biotechnology, Heinrich-Heine-University Düsseldorf, Universitätsstr. 1/Geb. 26.23, 40225 Düsseldorf, Germany., Temiz Artmann A; Institute for Bioengineering, University of Applied Sciences Aachen/Campus Juelich, Heinrich-Mussmannstr. 1, 52428 Jülich, Germany.

Publikováno v: Membranes [Membranes (Basel)] 2022 Dec 24; Vol. 13 (1). Date of Electronic Publication: 2022 Dec 24.

Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer.

Autor: Reimche I; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Yu H; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Ariantari NP; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Udayana University, Bali 80361, Indonesia., Liu Z; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Merkens K; Department of Chemistry, University of Cologne, 50923 Cologne, Germany., Rotfuß S; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany., Peter K; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany., Jungwirth U; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK., Bauer N; European Institute of Molecular Imaging, University of Münster, 48149 Münster, Germany., Kiefer F; European Institute of Molecular Imaging, University of Münster, 48149 Münster, Germany.; Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany., Neudörfl JM; Department of Chemistry, University of Cologne, 50923 Cologne, Germany., Schmalz HG; Department of Chemistry, University of Cologne, 50923 Cologne, Germany., Proksch P; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Teusch N; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 07; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 07.