Zobrazeno 1 - 10
of 740
pro vyhledávání: '"Teunis, B."'
Autor:
Jade Jansen, Stefanie Kroeze, Shirley Man, Matteo Andreini, Jan-Willem Bakker, Claudio Zamperini, Alessia Tarditi, Neeltje A. Kootstra, Teunis B. H. Geijtenbeek
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Latency reversal and subsequent elimination of the human immunodeficiency virus-1 (HIV-1) reservoir using a combination of compounds with different mechanisms of action are considered a promising tool for HIV-1 cure. Here, we analyzed HIV-1
Externí odkaz:
https://doaj.org/article/d0560039e44d47d4b396cbba95174d45
Akademický článek
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Akademický článek
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Autor:
Cees J. M. van Rijn, Killian E. Vlaming, Reinout A. Bem, Rob J. Dekker, Albert Poortinga, Timo Breit, Selina van Leeuwen, Wim A. Ensink, Kelly van Wijnbergen, John L. van Hamme, Daniel Bonn, Teunis B. H. Geijtenbeek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Nebulization of mRNA therapeutics can be used to directly target the respiratory tract. A promising prospect is that mucosal administration of lipid nanoparticle (LNP)-based mRNA vaccines may lead to a more efficient protection against respi
Externí odkaz:
https://doaj.org/article/3506da11f17d4bc1b2ecd6e5dd1c74ec
Autor:
Lieve E H van der Donk, Marta Bermejo-Jambrina, John L van Hamme, Mette M W Volkers, Ad C van Nuenen, Neeltje A Kootstra, Teunis B H Geijtenbeek
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011735 (2023)
SARS-CoV-2 causes COVID-19, an infectious disease with symptoms ranging from a mild cold to severe pneumonia, inflammation, and even death. Although strong inflammatory responses are a major factor in causing morbidity and mortality, superinfections
Externí odkaz:
https://doaj.org/article/c010de220744407b84ce2a6c90caee68
Autor:
Nienke H. van Teijlingen, Julia Eder, Ramin Sarrami-Forooshani, Esther M. Zijlstra-Willems, Jan-Paul W. R. Roovers, Elisabeth van Leeuwen, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Vaginal inflammation increases the risk for sexual HIV-1 transmission but underlying mechanisms remain unclear. In this study we assessed the impact of immune activation on HIV-1 susceptibility of primary human vaginal Langerhans cells (LCs)
Externí odkaz:
https://doaj.org/article/a7e0a62b0e6646fa90b1a7b878945d4e
Autor:
Stefanie Busold, Jaap H. Akkerdaas, Esther M. Zijlstra-Willems, Kees van der Graaf, Sander W. Tas, Esther C. de Jong, Ronald van Ree, Teunis B. H. Geijtenbeek
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundHouse dust mite (HDM) is a major cause of respiratory allergic diseases. Dendritic cells (DCs) play a central role in orchestrating adaptive allergic immune responses. However, it remains unclear how DCs become activated by HDM. Biochemical
Externí odkaz:
https://doaj.org/article/47308762de5b4460a73a6291b4593146
Autor:
Noémi Anna Nagy, Fernando Lozano Vigario, Rinske Sparrius, Toni M. M. van Capel, Ronald van Ree, Sander W. Tas, I. Jolanda M. de Vries, Teunis B. H. Geijtenbeek, Bram Slütter, Esther C. de Jong, for the DC4Balance consortium
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNanomedicine provides a promising platform for manipulating dendritic cells (DCs) and the ensuing adaptive immune response. For the induction of regulatory responses, DCs can be targeted in vivo with nanoparticles incorporating tolerogeni
Externí odkaz:
https://doaj.org/article/ab1fdaff4c404832a67c0aa30a27e388
Autor:
Killian E. Vlaming, Kelly van Wijnbergen, Tanja M. Kaptein, Monique Nijhuis, Neeltje J. Kootstra, Godelieve J. de Bree, Teunis B. Geijtenbeek
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundToll-like receptor (TLR) agonists have been investigated due to their potential dual effects as latency reverting agents and immune modulatory compounds in people living with HIV (PLWH). Here, we investigated whether co-stimulation of TLR7/
Externí odkaz:
https://doaj.org/article/3d6d51d6c6784f33a23a7a8927adba23
Autor:
Eric Eldering, Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Interferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphod
Externí odkaz:
https://doaj.org/article/31940c490bd64fc09c995d4d78516705