Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Teun Van Gelder"'
Publikováno v:
European Journal of General Practice, Vol 30, Iss 1 (2024)
Background Patients with impaired renal function are at an increased risk of dehydration due to vomiting, diarrhoea or fever (so-called sick days). Temporary medication adjustment during sick days is necessary and current initiatives and information
Externí odkaz:
https://doaj.org/article/fe582a7e616a4999aa6afd9966c60fda
Autor:
Peter W. Nickerson, Georg A. Böhmig, Steve Chadban, Deepali Kumar, Roslyn B. Mannon, Teun van Gelder, James C. Lee, Scott Adler, Edward Chong, Arjang Djamali
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Chronic active antibody-mediated rejection (AMR) is a major cause of graft loss with no approved drugs for its treatment. Currently, off-label regimens are used, reflecting the high unmet need for effective therapies based on well
Externí odkaz:
https://doaj.org/article/7a1e094bc5104f2185b9a932e3db2b7f
Autor:
Aleixandra Mendoza Rojas, MSc, Jeroen G.H.P. Verhoeven, MD, Ronella de Kuiper, BSc, Marian C. Clahsen-van Groningen, MD, PhD, Karin Boer, PhD, Dennis A. Hesselink, MD, PhD, Teun van Gelder, MD, PhD, Nicole M. van Besouw, PhD, Carla C. Baan, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 5, p e1478 (2023)
Background. Memory T cells are important mediators of transplant rejection but are not routinely measured before or after kidney transplantation. The aims of this study were as follows: (1) validate whether pretransplant donor-reactive memory T cells
Externí odkaz:
https://doaj.org/article/5637f8ddc18f464e8be94581326bb8e6
Autor:
Aleixandra Mendoza Rojas, Teun van Gelder, Ronella de Kuiper, Derek Reijerkerk, Marian C. Clahsen-van Groningen, Dennis A. Hesselink, Carla C. Baan, Nicole M. van Besouw
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Pre-transplant screening focuses on the detection of anti-HLA alloantibodies. Previous studies have shown that IFN-γ and IL-21 producing T cells are associated with the development of acute rejection (AR). The aim of this study, was to asse
Externí odkaz:
https://doaj.org/article/8db403cdf73c4b05a4654cd6a3cdb0e9
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cytochrome P450 3A (CYP3A) subfamily enzymes are involved in the metabolism of 40% of drugs in clinical use. Twin studies have indicated that 66% of the variability in CYP3A4 activity is hereditary. Yet, the complexity of the CYP3A locus and the lack
Externí odkaz:
https://doaj.org/article/095cfae0737147a89d788acdd098a335
Autor:
Alan Abdulla, Annemieke Dijkstra, Nicole G. M. Hunfeld, Henrik Endeman, Soma Bahmany, Tim M. J. Ewoldt, Anouk E. Muller, Teun van Gelder, Diederik Gommers, Birgit C. P. Koch
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-12 (2020)
Abstract Background Early and appropriate antibiotic dosing is associated with improved clinical outcomes in critically ill patients, yet target attainment remains a challenge. Traditional antibiotic dosing is not suitable in critically ill patients,
Externí odkaz:
https://doaj.org/article/0f154ec3e09242a69e716dee85ab5a45
Autor:
Denise Karin Beck, Mirjam Tielen, Marloes Rechards, Reinier Timman, Charlotte Boonstra, Josette Versteegh, Jacqueline van de Wetering, Robert Zietse, Teun van Gelder, Willem Weimar, Jan van Saase, Jan van Busschbach, Emma Kay Massey
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background After kidney transplantation non-adherence and inadequate self-management undermine clinical outcomes and quality of life. Both have been demonstrated to be substantial in all age groups. However, interventions promoting adherence
Externí odkaz:
https://doaj.org/article/639438a235224f8e8ef7abc04a852ab9
Autor:
Florine A. Berger, Heleen van der Sijs, Matthijs L. Becker, Teun van Gelder, Patricia M. L. A. van den Bemt
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The exact risk of developing QTc-prolongation when using a combination of QTc-prolonging drugs is still unknown, making it difficult to interpret these QT drug-drug interactions (QT-DDIs). A tool to identify high-risk patients is
Externí odkaz:
https://doaj.org/article/510aaaa02493400f90fca56dde66c0eb
Publikováno v:
Therapeutic Advances in Drug Safety, Vol 12 (2021)
Introduction: The handling of drug–drug interactions regarding QTc-prolongation (QT-DDIs) is not well defined. A clinical decision support (CDS) tool will support risk management of QT-DDIs. Therefore, we studied the effect of a CDS tool on the pro
Externí odkaz:
https://doaj.org/article/c5f197d92e7844c39b0c1c4a9652539a
Autor:
Qian Niu, Aleixandra Mendoza Rojas, Marjolein Dieterich, Dave L. Roelen, Marian C. Clahsen-van Groningen, Lanlan Wang, Teun van Gelder, Dennis A. Hesselink, Nicole M. van Besouw, Carla C. Baan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: FoxP3+ follicular regulatory T cells (Tfr) have been identified as the cell population controlling T follicular helper (Tfh) cells and B cells which, are both involved in effector immune responses against transplanted tissue.Methods: To u
Externí odkaz:
https://doaj.org/article/497e142c88d241c6844ffd0e11838d1c