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Akademický článek
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Autor:
Matthew Higgins, Mojca Kristan, Emma L. Collins, Louisa A. Messenger, Jamille G. Dombrowski, Leen N. Vanheer, Debbie Nolder, Christopher J. Drakeley, William Stone, Almahamoudou Mahamar, Teun Bousema, Michael Delves, Janvier Bandibabone, Sévérin N’Do, Chimanuka Bantuzeko, Bertin Zawadi, Thomas Walker, Colin J. Sutherland, Claudio R. F. Marinho, Mary M. Cameron, Taane G. Clark, Susana Campino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Robust diagnostic tools and surveillance are crucial for malaria control and elimination efforts. Malaria caused by neglected Plasmodium parasites is often underestimated due to the lack of rapid diagnostic tools that can accurately detect t
Externí odkaz:
https://doaj.org/article/a62e65a32f43462287335f4c454f7c0a
Autor:
Palang Chotsiri, Almahamoudou Mahamar, Halimatou Diawara, Pius S. Fasinu, Kalifa Diarra, Koualy Sanogo, Teun Bousema, Larry A. Walker, Joelle M. Brown, Alassane Dicko, Roly Gosling, Ingrid Chen, Joel Tarning
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Primaquine (PQ) is the prototype 8-aminoquinoline drug, a class which targets gametocytes and hypnozoites. The World Health Organization (WHO) recommends adding a single low dose of primaquine to the standard artemisinin-based com
Externí odkaz:
https://doaj.org/article/015bdc6bd7bf43d5816e49d619b26310
Autor:
Seyi Soremekun, Bakary Conteh, Abdoullah Nyassi, Harouna M. Soumare, Blessed Etoketim, Mamadou Ousmane Ndiath, John Bradley, Umberto D’Alessandro, Teun Bousema, Annette Erhart, Marta Moreno, Chris Drakeley
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background In 2022 the WHO recommended the discretionary expansion of the eligible age range for seasonal malaria chemoprevention (SMC) to children older than 4 years. Older children are at lower risk of clinical disease and severe malaria s
Externí odkaz:
https://doaj.org/article/f1e10a238f444ae5b5ec191999ae2b5e
Autor:
Sara Lynn Blanken, Aissata Barry, Kjerstin Lanke, Moussa Guelbeogo, Alphonse Ouedraogo, Issiaka Soulama, Sam Aboubacar Coulibaly, Karina Teelen, Wouter Graumans, Elin Dumont, Will Stone, Jordache Ramjith, Matthias Marti, Carolina M. Andrade, Chris Drakeley, Katharine Collins, Alfred Tiono, Teun Bousema
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105190- (2024)
Summary: Background: Plasmodium blood-stage parasites balance asexual multiplication with gametocyte development. Few studies link these dynamics with parasite genetic markers in vivo; even fewer in longitudinally monitored infections. Environmental
Externí odkaz:
https://doaj.org/article/7336c1a473d54aea86a08f6e7e2795a8
Autor:
Elifaged Hailemeskel, Surafel K. Tebeje, Jordache Ramjith, Temesgen Ashine, Kjerstin Lanke, Sinknesh W. Behaksra, Tadele Emiru, Tizita Tsegaye, Abrham Gashaw, Soria Kedir, Wakweya Chali, Endashaw Esayas, Temesgen Tafesse, Haile Abera, Mikiyas Gebremichael Bulto, Girma Shumie, Beyene Petros, Hassen Mamo, Chris Drakeley, Endalamaw Gadisa, Teun Bousema, Fitsum G. Tadesse
Publikováno v:
International Journal of Infectious Diseases, Vol 143, Iss , Pp 107010- (2024)
Objective: A 15-month longitudinal study was conducted to determine the duration and infectivity of asymptomatic qPCR-detected Plasmodium falciparum and Plasmodium vivax infections in Ethiopia. Method: Total parasite and gametocyte kinetics were dete
Externí odkaz:
https://doaj.org/article/b8f97a3a49f44b6ca76bacbd3fa9f3a0
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Malaria is initiated when infected anopheline mosquitoes inoculate sporozoites as they probe for blood. It is thought that all infected mosquitoes are equivalent in terms of their infectious potential, with parasite burden having no role in
Externí odkaz:
https://doaj.org/article/36d12afc8d644f59bbdf13589a8d3cb6
Autor:
Balotin Fogang, Lionel Lellouche, Sukai Ceesay, Sainabou Drammeh, Fatou K. Jaiteh, Marc-Antoine Guery, Jordi Landier, Cynthia P. Haanappel, Janeri Froberg, David Conway, Umberto D’Alessandro, Teun Bousema, Antoine Claessens
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Chronic carriage of asymptomatic low-density Plasmodium falciparum parasitaemia in the dry season may support maintenance of acquired immunity that protects against clinical malaria. However, the relationship between chronic low-d
Externí odkaz:
https://doaj.org/article/8e3447bace1142dd84e6d99a5862b997
Autor:
Maartje R. Inklaar, Roos M. de Jong, Ezra T. Bekkering, Hikaru Nagaoka, Felix L. Fennemann, Karina Teelen, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Rianne Stoter, C. Richter King, Nicholas I. Proellochs, Teun Bousema, Eizo Takashima, Takafumi Tsuboi, Matthijs M. Jore
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Malaria transmission-blocking vaccines (TBVs) aim to induce antibodies that block Plasmodium parasite development in the mosquito midgut, thus preventing mosquitoes from becoming infectious. While the Pro-domain and first of fourteen 6-Cyste
Externí odkaz:
https://doaj.org/article/873417ee2eae4bd1826b51bf24506c7a
Autor:
Chiara Andolina, Wouter Graumans, Moussa Guelbeogo, Geert-Jan van Gemert, Jordache Ramijth, Soré Harouna, Zongo Soumanaba, Rianne Stoter, Marga Vegte-Bolmer, Martina Pangos, Photini Sinnis, Katharine Collins, Sarah G Staedke, Alfred B Tiono, Chris Drakeley, Kjerstin Lanke, Teun Bousema
Publikováno v:
eLife, Vol 12 (2024)
It is currently unknown whether all Plasmodium falciparum-infected mosquitoes are equally infectious. We assessed sporogonic development using cultured gametocytes in the Netherlands and naturally circulating strains in Burkina Faso. We quantified th
Externí odkaz:
https://doaj.org/article/be98e34cc5dd4122ad803aa3d9086ded