Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tetyana Kudlyk"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Golgi-associated retrograde protein (GARP) is an evolutionary conserved heterotetrameric protein complex that tethers endosome-derived vesicles and is vital for Golgi glycosylation. Microscopy and proteomic approaches were employed to investigate def
Externí odkaz:
https://doaj.org/article/e1bfa85481204be89812639e34330c6b
Autor:
Zinia D’Souza, Jessica Bailey Blackburn, Tetyana Kudlyk, Irina D. Pokrovskaya, Vladimir V. Lupashin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The conserved oligomeric complex (COG) is a multi-subunit vesicle tethering complex that functions in retrograde trafficking at the Golgi. We have previously demonstrated that the formation of enlarged endo-lysosomal structures (EELSs) is one of the
Externí odkaz:
https://doaj.org/article/a586133a4ccd4d75b4aec0fdacb3a45d
GARP is an evolutionary conserved heterotetrameric protein complex that is thought to tether endosome-derived vesicles and promotes their fusion in the trans-Golgi network. We have previously discovered the GARP’s role in maintaining Golgi glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa8d65781f49b517bb90ddebb5cadf1d
https://doi.org/10.1101/2022.07.22.501184
https://doi.org/10.1101/2022.07.22.501184
Publikováno v:
Molecular Biology of the Cell
The Golgi apparatus is a central hub for intracellular protein trafficking and glycosylation. Steady-state localization of glycosylation enzymes is achieved by a combination of mechanisms involving retention and vesicle recycling, but the machinery g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d712b5c0d9e5499410b8a30a0504129
https://doi.org/10.1101/2020.12.21.423858
https://doi.org/10.1101/2020.12.21.423858
Autor:
Vladimir Lupashin, Tetyana Kudlyk, Irina D. Pokrovskaya, Jessica Bailey Blackburn, Zinia D'Souza
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
The conserved oligomeric complex (COG) is a multi-subunit vesicle tethering complex that functions in retrograde trafficking at the Golgi. We have previously demonstrated that the formation of enlarged endo-lysosomal structures (EELSs) is one of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e065a774388a562c6098f1701bc3a507
Publikováno v:
Traffic (Copenhagen, Denmark). 19(6)
The conserved oligomeric Golgi (COG) complex controls membrane trafficking and ensures Golgi homeostasis by orchestrating retrograde vesicle trafficking within the Golgi. Human COG defects lead to severe multisystemic diseases known as COG-congenital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0392e751e71639ddd66eb987f8bf8c6a
https://pubmed.ncbi.nlm.nih.gov/29573151
https://pubmed.ncbi.nlm.nih.gov/29573151
Autor:
Tetyana Kudlyk, Vladimir Lupashin, Irina D. Pokrovskaya, Leslie K. Climer, Frederick M. Hughson, Gregory R. Shimamura, Jun Yong Ha, Philip D. Jeffrey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 2014. Vol. 111, № 44. P. 15762-15767
The conserved oligomeric Golgi (COG) complex is required, along with SNARE and Sec1/Munc18 (SM) proteins, for vesicle docking and fusion at the Golgi. COG, like other multisubunit tethering complexes (MTCs), is thought to function as a scaffold and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3691040740e814950f7ebb6f070fa9cb
https://doi.org/10.1073/pnas.1414829111
https://doi.org/10.1073/pnas.1414829111
Autor:
Hiroyuki Arai, Taki Nishimura, Tetyana Kudlyk, Rieko Yachi, Tomohiko Taguchi, Yasunori Uchida, Takao Inoue, Vladimir Lupashin
Publikováno v:
Molecular Biology of the Cell
OSBP regulates the Golgi cholesterol level. This study demonstrates that OSBP and cholesterol are essential for localization of Golgi v-SNAREs. Knockdown of ArfGAP1 restores v-SNARE localization in OSBP-depleted cells, suggesting that OSBP-regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae16cf448b8db98cb176af33fdf88e02
http://europepmc.org/articles/PMC3826991
http://europepmc.org/articles/PMC3826991
Autor:
Rose Willett, Jessica Bailey Blackburn, Wei Wang, Leslie K. Climer, Tetyana Kudlyk, Vladimir Lupashin, Irina D. Pokrovskaya
Publikováno v:
Scientific Reports
The conserved oligomeric Golgi (COG) complex is a peripheral membrane protein complex which orchestrates tethering of intra-Golgi vesicles. We found that COG1-4 (lobe A) and 5–8 (lobe B) protein assemblies are present as independent sub-complexes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae561ee6b5bedc9f22259a161e5c6e08
https://pubmed.ncbi.nlm.nih.gov/27385402
https://pubmed.ncbi.nlm.nih.gov/27385402
Publikováno v:
Frontiers in Cell and Developmental Biology
Unexpectedly, members of the Rab VI subfamily exhibit considerable variation in their effects on Golgi organization and trafficking. By fluorescence microscopy, neither depletion nor overexpression of the GDP-locked form of Rab6a/a’, the first tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c47b879f5ef178fd071057a94b07fb0
http://europepmc.org/articles/PMC4771738
http://europepmc.org/articles/PMC4771738