Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tetyana Kobets"'
Publikováno v:
Foods, Vol 11, Iss 18, p 2828 (2022)
Commonly consumed foods and beverages can contain chemicals with reported carcinogenic activity in rodent models. Moreover, exposures to some of these substances have been associated with increased cancer risks in humans. Food-borne carcinogens span
Externí odkaz:
https://doaj.org/article/8db76a66941b4892a67d46cd36b08278
Autor:
Yahya Sohrabi, Helena Havelková, Tetyana Kobets, Matyáš Šíma, Valeriya Volkova, Igor Grekov, Taťána Jarošíková, Iryna Kurey, Jarmila Vojtíšková, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2282 (2013)
BACKGROUND: L. tropica can cause both cutaneous and visceral leishmaniasis in humans. Although the L. tropica-induced cutaneous disease has been long known, its potential to visceralize in humans was recognized only recently. As nothing is known abou
Externí odkaz:
https://doaj.org/article/afe245a0a2154623b2d311010dda6c2c
Autor:
Tetyana Kobets, Helena Havelková, Igor Grekov, Valeriya Volkova, Jarmila Vojtíšková, Martina Slapničková, Iryna Kurey, Yahya Sohrabi, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1667 (2012)
BACKGROUND: Leishmaniasis is a disease caused by protozoan parasites of genus Leishmania. The frequent involvement of Leishmania tropica in human leishmaniasis has been recognized only recently. Similarly as L. major, L. tropica causes cutaneous leis
Externí odkaz:
https://doaj.org/article/1b843d864a224403a831bc6a115c8981
Publikováno v:
International Journal of Toxicology. 41:297-311
DNA damage is an established initiating event in the mutagenicity and carcinogenicity of genotoxic chemicals. Accordingly, assessment of this endpoint is critical for chemicals which are being developed for use in humans. To assess the ability of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf78ced57e328c602706c5c990183042
https://doi.org/10.1177/10915818221093583
https://doi.org/10.1177/10915818221093583
Publikováno v:
Toxicology Research and Application, Vol 6 (2022)
Acrylonitrile, an industrial chemical, is a multisite carcinogen in rats and mice, producing tumors in four tissues with barrier function, that is, brain, forestomach, Zymbal’s gland, and Harderian gland. To assess mechanism(s) of action (MoA) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9cf1a978621018aff2e246915f7b2b
https://doaj.org/article/ce3d17496bc440a3bcb64ac45466cf7b
https://doaj.org/article/ce3d17496bc440a3bcb64ac45466cf7b
Autor:
Gary M. Williams, Tetyana Kobets
Publikováno v:
Chemico-Biological Interactions. 301:88-111
In the deliberations over many years on the question of thresholds for the carcinogenicity of chemicals, the dominant paradigm has been the linear no-threshold (LNT) model, derived from concepts formulated in radiation mutagenicity. Based on the anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5743ab90dca9fd5c47d1a7c535c41192
https://doi.org/10.1016/j.cbi.2018.11.011
https://doi.org/10.1016/j.cbi.2018.11.011
Autor:
Tetyana Kobets, Ivan Rusyn, Oksana Kosyk, Lauren Lewis, Wanda Bodnar, Grace A. Chappell, Natalia Y. Tretyakova, Igor P. Pogribny, Bridget E. O’Brian, Dewakar Sangaraju
Publikováno v:
Archives of Toxicology. 93:791-800
Exposure to environmental chemicals has been shown to have an impact on the epigenome. One example is a known human carcinogen 1,3-butadiene which acts primarily by a genotoxic mechanism, but also disrupts the chromatin structure by altering patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70612e105fbea8f0d9d849c56143ba41
https://doi.org/10.1007/s00204-018-2374-x
https://doi.org/10.1007/s00204-018-2374-x
Autor:
A. Wallace Hayes, Tetyana Kobets
Hayes'Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition
Autor:
B. Smith, Jian-Dong Duan, Sylvain Etter, Gary M. Williams, Tetyana Kobets, Michael J. Iatropoulos, Christina Hickey, Klaus D. Brunnemann
Publikováno v:
Food and Chemical Toxicology. 115:228-243
Genotoxicity of flavor and fragrance materials was assessed in Turkey Egg Genotoxicity Assay (TEGA) using 32P-nucleotide postlabeling (NPL) and comet assays to detect hepatic DNA adducts and strand breaks. Twenty materials having results in GADD45a-G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df798dcaacde9bd94ec66f1494ed2fba
https://doi.org/10.1016/j.fct.2018.03.015
https://doi.org/10.1016/j.fct.2018.03.015
Autor:
Esther Vock, Tetyana Kobets, Klaus D. Brunnemann, Jian-Dong Duan, Ulrich Deschl, Gary M. Williams, Michael J. Iatropoulos
Publikováno v:
Experimental and Toxicologic Pathology. 69:533-546
Chicken egg fetal livers were evaluated for histopathological changes produced by four genotoxic hepatocarcinogens: 2-acetylaminofluorene (AAF), aflatoxin B1 (AFB1), benzo[a]pyrene (BaP), diethylnitrosamine (DEN); four structurally related non- or we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f1e39a4548d2c9f535f513d2f4d017
https://doi.org/10.1016/j.etp.2017.04.011
https://doi.org/10.1016/j.etp.2017.04.011