Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tetuya Mimura"'
Autor:
Ken Osanai, Tetuya Mimura, Fusako Kito, Emi Ota, Shinichi Kawajiri, Masunobu Sugimura, Yoshiyuki Yoneda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:2663-2666
We synthesized diaminobutane derivatives as potent Ca 2+ -permeable AMPA receptor antagonists with non-hypotensive activity. Compound 10c showed selective Ca 2+ -permeable AMPA receptor antagonist activity and neuroprotective effects in transient glo
Autor:
Atushi Hasegawa, Sumie Katano, Tetuya Mimura, Yoshiyuki Yoneda, Emi Takano, Shinichi Kawajiri, Fusako Kito
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:1261-1264
In order to obtain non-hypotensive and Ca2+-permeable AMPA receptor antagonists, we have synthesized a series of 1,4-bis(4-piperidinylmethyl)diaminobutanes. Compounds 13b, c, f had desirable properties.
Autor:
Fusako Kito, Sumie Katano, Tetuya Mimura, Shinichi Kawajiri, Emi Takano, Yoshiyuki Yoneda, Atushi Hasegawa
Publikováno v:
ChemInform. 32
In order to obtain non-hypotensive and Ca2+-permeable AMPA receptor antagonists, we have synthesized a series of 1,4-bis(4-piperidinylmethyl)diaminobutanes. Compounds 13b, c, f had desirable properties.
Autor:
Shinichi Kawajiri, Yoshiyuki Yoneda, Ken Osanai, Tetuya Mimura, Fusako Kito, Emi Ota, Masunobu Sugimura
Publikováno v:
ChemInform. 33
We synthesized diaminobutane derivatives as potent Ca 2+ -permeable AMPA receptor antagonists with non-hypotensive activity. Compound 10c showed selective Ca 2+ -permeable AMPA receptor antagonist activity and neuroprotective effects in transient glo
Autor:
Masunobu Sugimura, Masaki Saito, Takanori Yasukouchi, Shinichi Kawajiri, Masayuki Ito, Kei-ichi Kawagoe, Tetuya Mimura, Fusako Kito, Toshiaki Tatematu, Yoshiyuki Yoneda
Publikováno v:
ChemInform. 33
Autor:
Masaki Saito, Yoshiyuki Yoneda, Shinichi Kawajiri, Kei-ichi Kawagoe, Toshiaki Tatematu, Masayuki Ito, Takanori Yasukouchi, Tetuya Mimura, Masunobu Sugimura, Fusako Kito
Publikováno v:
Bioorganicmedicinal chemistry. 10(5)
We designed and synthesized a series of the polyamine derivatives as potent Ca2+-permeable AMPA receptor antagonists. In the course of this study, we found that the polyamine derivatives exhibited strong hypotensive activity which was undesirable act