Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tetsuya Oshikawa"'
Autor:
SangJae Bae, Masato Okamoto, Ichiro Katayama, Yasuhiro Horiuchi, Mitsunobu Sato, Tetsuya Oshikawa
Publikováno v:
Archives of Dermatological Research. 298:163-173
Bacterial stimulation may serve to control atopic disorders such as atopic dermatitis (AD) through inducement of Th1 cell-mediated immune response. The lipoteichoic acid (LTA)-related molecule (okLTA) from streptococcal preparation, OK-432, has been
Autor:
Tomoyuki Tano, Motoo Saito, Mitsunobu Sato, Sharif Uddin Ahmed, Akiko Sasai, Yoshiki Ryoma, Masato Okamoto, Shin Kan, Yoichiro Moriya, Tetsuya Oshikawa
Publikováno v:
International Immunopharmacology. 6:764-773
We examined the role of nitric oxide (NO) induced by OK-432, a streptococcal immunotherapeutic agent, in anti-tumor effects of the OK-432 by in vitro and in vivo experiments using an NO synthase inhibitor, N-monomethyl-l-arginine acetate (NMA). The i
Autor:
Masato Okamoto, Yoichiro Moriya, Motoo Saito, Shizuo Akira, Mitsunobu Sato, Akiko Sasai, Yoshiki Ryoma, Tetsuya Oshikawa, Tomoyuki Tano, Shin Kan
Publikováno v:
Journal of Immunotherapy. 29:143-150
OK-432 is a Streptococcus-derived immunotherapeutic agent for malignancies. Our group has tried to identify the effective components of OK-432 and has succeeded in isolating a lipoteichoic acid-related preparation designated as OK-PSA, which is a str
Autor:
Shin Kan, Kensuke Miyake, Tomoyuki Tano, Motoo Saito, Tetsuya Oshikawa, Sharif Uddin Ahmed, Yoshiki Ryoma, Yoichiro Moriya, Akiko Sasai, Sachiko Akashi, Masato Okamoto, Mitsunobu Sato
Publikováno v:
Journal of Immunotherapy. 29:78-86
It has previously been reported by our group that Toll-like receptor (TLR) 4 is involved in anticancer immunity induced by OK-432, a Streptococcus-derived immunotherapeutic agent. However the detailed mechanism of the OK-432-induced immune response v
Autor:
Sharif Uddin Ahmed, Masato Okamoto, Coralia Osorio, Yoshinori Fujimoto, Freddy A. Ramos, Carmenza Duque, Takaaki Sagawa, Mitsunobu Sato, Tetsuya Oshikawa, Cristina Garzon, Yoshihisa Takaishi
Publikováno v:
J. Nat. Prod.. 68(No. 4):502-505
Five cyclobutane dimers, achyrodimers A-E (1-5), along with 11 known compounds were isolated from the methanol extract of the Colombian medicinal plant Achyrocline bogotensis. Their structures were elucidated by spectroscopy. Several of these compoun
Autor:
Soko Kasai, Sharif Uddin Ahmed, Masato Okamoto, Akiko Sasai, Yoshihiro Uto, Tetsuya Oshikawa, Sachiko Furuichi, Tomoyuki Tano, Hitoshi Hori, Mitsunobu Sato, Hideko Nagasawa, Shin Kan
Publikováno v:
International Journal of Cancer. 116:571-578
We investigated in the current study the effect of TX-1877, a bifunctional hypoxic cell radiosensitizer, in augmenting anticancer host response. In the syngeneic squamous cell carcinoma-bearing mouse model, a single administration of TX-1877 signific
Autor:
Mitsunobu Sato, Go Ohe, Osamu Takeuchi, Sachiko Akashi, Kunisuke Himeno, Shizuo Akira, Masato Okamoto, Kensuke Miyake, Tetsuya Oshikawa, Shinya Ohkubo, Tomoyuki Tano, Sachiko Furuichi, Sharif Uddin Ahmed
Publikováno v:
Clinical and Vaccine Immunology. 11:483-495
A 55-kDa protein named AILb-A, isolated from the seed extract of Aeginetia indica L., a parasitic plant, induces a Th1-type T-cell response and elicits a marked antitumor effect in tumor-bearing mice. In the present study, we examined the role of Tol
Autor:
Hideo Yoshida, Sachiko Furuichi, Motoo Saito, Masato Okamoto, Sharif Uddin Ahmed, Yoshiki Ryoma, Tetsuya Oshikawa, Shuzo Matsubara, Hidetomo Nishikawa, Yoichiro Moriya, Mitsunobu Sato, Go Ohe
Publikováno v:
International Immunopharmacology. 3:643-655
We have previously isolated a lipoteichoic acid (LTA)-related molecule (OK-PSA) from OK-432, a streptococcal agent, by affinity chromatography on a CNBr-activated Sepharose 4B bound TS-2 monoclonal antibody (mAb) that neutralizes the interferon (IFN)
Autor:
Tomoyuki Tano, Hidetomo Nishikawa, Masato Okamoto, Yoichiro Moriya, Sachiko Furuichi, Motoo Saito, Tetsuya Oshikawa, Go Ohe, Mitsunobu Sato, Sharif Uddin Ahmed, Hideo Yoshida
Publikováno v:
Cancer Immunology, Immunotherapy. 50:408-416
We isolated the lipoteichoic-acid-related molecule (OK-PSA) from OK-432, a streptococcal preparation, by affinity chromatography on CNBr-activated Sepharose-4B-bound monoclonal antibody TS-2, which neutralizes the interferon (IFN)-gamma-inducing acti
Autor:
Masato Okamoto, Hidetomo Nishikawa, Sharif Uddin Ahmed, Tetsuya Oshikawa, Go Ohe, Sachiko Furuichi, Mitsunobu Sato, Hideo Yoshida, Tomoyuki Tano
Publikováno v:
Japanese jornal of Head and Neck Cancer. 27:651-657
Toll-like recetor (TLR) 4遺伝子発現と免疫療法剤 (OK-432およびその活性成分OK-PSA) の効果との関連につき検討した。OK-PSAの抗腫瘍免疫活性はTLR4の発現に依存して発揮される事が示された。OK-432