Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Tetsuya Konishi"'
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 10, Iss 3, Pp 245-251 (2020)
Abstracts: Echigoshirayukidake is an edible mushroom found in Uonuma, Japan in 1994. It was assigned to a new species of Basidiomycetes (BDM-X) but is uniquely defect of forming bashidium. The high antioxidant activity and β-glucan content of BDM-X
Externí odkaz:
https://doaj.org/article/32c19e7f42254ce8a439d350d01584ad
Autor:
Toshio Sakamoto, Zhenshi Li, Ayaka Nishida, Asako Kadokawa, Takayuki Yoshida, Naoki Wada, Seiichi Matsugo, Yutaka Nakamura, Shinji Sato, Tetsuya Konishi
Publikováno v:
Frontiers in Bioscience-Elite, Vol 14, Iss 2, p 10 (2022)
Basidiomycetes-X, of which Japanese vernacular name is Echigoshirayukidake, is a local speciality mushroom found and cultivated in Japan that has been distributed as a precious cuisine material or as a functional food with medicinal properties. Antio
Externí odkaz:
https://doaj.org/article/7acb45157c394e44b5b1b6d94308684d
Autor:
Toshio Sakamoto, Ayaka Nishida, Naoki Wada, Yutaka Nakamura, Shinji Sato, Tetsuya Konishi, Seiichi Matsugo
Publikováno v:
Molecules, Vol 25, Iss 21, p 4879 (2020)
Three pyrrole alkaloid derivatives were isolated from the edible mushroom Basidiomycetes-X (Echigoshirayukidake) by water extraction followed by ethyl acetate fractionation. The chemical structures determined by MS and NMR were 4-[2-formyl-5-(hydroxy
Externí odkaz:
https://doaj.org/article/87eae671643d439399d6570683e55248
Autor:
Vijayasree V. Giridharan, Vengadeshprabhu Karupppagounder, Somasundaram Arumugam, Yutaka Nakamura, Ashrith Guha, Tatiana Barichello, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A. Thandavarayan
Publikováno v:
Cells, Vol 9, Iss 3, p 597 (2020)
Aging is a predominant risk factor for the development and progression of cardiovascular complications. Physiologically and anatomically, the heart undergoes numerous changes that result in poor cardiac function in the elderly population. Recently, s
Externí odkaz:
https://doaj.org/article/6425c74016394923877d0523003a4575
Autor:
Naoto Tatewaki, Hiroshi Nishida, Masaaki Yoshida, Hidehiro Ando, Seizo Kondo, Toshiyuki Sakamaki, Tetsuya Konishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 2, Pp 138-148 (2013)
We have previously reported that schisandrin B (SchB) is a specific inhibitor of ATR (ataxia telangiectasia and Rad-3-related) protein kinase. Since SchB consists of a mixture of its diastereomers gomisin N (GN) and γ-schisandrin (γ-Sch), the inhib
Externí odkaz:
https://doaj.org/article/53feacc6b0ac4f8ea1b8a92e80c0e067
Autor:
Vengadeshprabhu Karuppagounder, Vijayasree V Giridharan, Somasundaram Arumugam, Remya Sreedhar, Suresh S Palaniyandi, Prasanna Krishnamurthy, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A Thandavarayan
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152922 (2016)
The aim of this study was to investigate the role of macrophage polarization in aging heart. Macrophage differentiation is pathogenically linked to many inflammatory and immune disorders. It is often preceded by myocardial inflammation, which is char
Externí odkaz:
https://doaj.org/article/7f586af7a28c48748d565827c5dca0d6
Autor:
Naoto Tatewaki, Tetsuya Konishi, Yuki Nakajima, Miyako Nishida, Masafumi Saito, Takahiro Eitsuka, Toshiyuki Sakamaki, Nobuo Ikekawa, Hiroshi Nishida
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147570 (2016)
Ataxia telangiectasia mutated (ATM) kinase plays a crucial role as a master controller in the cellular DNA damage response. Inhibition of ATM leads to inhibition of the checkpoint signaling pathway. Hence, addition of checkpoint inhibitors to antican
Externí odkaz:
https://doaj.org/article/59c9d1cde60b4be2a4e67f8b6e3a74db
Autor:
Hiroshi Nishida, Megumi Kushida, Yuki Nakajima, Yoshihiro Ogawa, Naoto Tatewaki, Shinji Sato, Tetsuya Konishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 1, Pp 73-81 (2007)
Neurodegenerative brain disorders such as Alzheimer’s disease (AD) have been well investigated. However, significant methods for the treatment of the promotion and progression of AD are unavailable to date. Recent studies suggested that the redox i
Externí odkaz:
https://doaj.org/article/2acf5882c5854c2592d4684527b84aa4
Publikováno v:
Journal of Pharmacological Sciences, Vol 105, Iss 4, Pp 342-352 (2007)
Cellular and tissue injury associated with reactive oxygen species (ROS) has been reported in many kinds of disorders. While the antioxidant enzymes play critical roles in inhibiting the ROS-mediated injury, glutathione peroxidase (GPx) is scavenging
Externí odkaz:
https://doaj.org/article/fb79e668079d4127b411d783c8ed18eb
Autor:
Rajarajan A Thandavarayan, Vijayasree V Giridharan, Somasundaram Arumugam, Kenji Suzuki, Kam Ming Ko, Prasanna Krishnamurthy, Kenichi Watanabe, Tetsuya Konishi
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119214 (2015)
Doxorubicin (Dox) is a highly effective antineoplastic drug. However, Dox-induced apoptosis in cardiomyocytes leads to irreversible degenerative cardiomyopathy, which limits Dox clinical application. Schisandrin B (Sch B), a dibenzocyclooctadiene der
Externí odkaz:
https://doaj.org/article/0fcd12f50b214fefb49827e1630aad50