Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Tetsuya, Matsuguchi"'
Autor:
Tomokazu Ohnishi, Toshiaki Nakamura, Kaori Shima, Kazuyuki Noguchi, Norika Chiba, Tetsuya Matsuguchi
Publikováno v:
Journal of Oral Biosciences. 64:229-236
The oral cavity is one of the main entry sites for SARS-CoV-2. Gingival keratinocytes express transmembrane serine protease 2 (TMPRSS2), responsible for priming the SARS-CoV-2 spike protein. We investigated whether periodontitis increased the express
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 10, Pp 1806-1820 (2016)
Chemokines are a family of cytokines inducing cell migration and inflammation. Recent reports have implicated the roles of chemokines in cell differentiation. However, little is known about the functional roles of chemokines in adipocytes. Here, we e
Externí odkaz:
https://doaj.org/article/027a815ae34e44b2926b70fda2b546d7
Autor:
Muhammad Subhan Amir, Norika Chiba, Chang Hwan Seong, Joji Kusuyama, Nahoko Eiraku, Tomokazu Ohnishi, Norifumi Nakamura, Tetsuya Matsuguchi
Publikováno v:
Journal of Cellular Physiology. 237:2183-2197
Bone homeostasis is regulated by bone morphogenic proteins (BMPs), among which BMP9 is one of the most osteogenic. Here, we have found that BMP9 rapidly increases the protein expression of hypoxia-inducible factor-1α (HIF-1α) in osteoblasts under n
Autor:
Kiyohide Ishihata, Chang-Hwan Seong, Toshiro Kibe, Kenta Nakazono, Fredy Mardiyantoro, Ryohei Tada, Masahiro Nishimura, Tetsuya Matsuguchi, Norifumi Nakamura
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12633
Lipoteichoic acid (LTA) and lipopolysaccharide (LPS) are cell wall components of Gram-positive and Gram-negative bacteria, respectively. Notably, oral microflora consists of a variety of bacterial species, and osteomyelitis of the jaw caused by denta
Autor:
Mitsuhiro Hisadome, Tetsuya Matsuguchi, Norika Chiba, Kusuyama Joji, Tomokazu Ohnishi, Muhammad Subhan Amir, Takuro Kanekura
Publikováno v:
Journal of Cellular Biochemistry. 122:1141-1156
Ultraviolet radiation is one of the standard treatment selections for psoriasis. interferon (IFN)-γ and IFN-γ-induced CXCL10, which are highly expressed by keratinocytes in psoriasis lesion, are therapeutic targets for psoriasis. In this study, we
Publikováno v:
Biochemical Journal. 477:1795-1811
The glycolytic system is selected for ATP synthesis not only in tumor cells but also in differentiated cells. Differentiated osteoblasts also switch the dominant metabolic pathway to aerobic glycolysis. We found that primary osteoblasts increased exp
Publikováno v:
FEBS lettersReferences. 596(13)
Bone morphogenetic proteins (BMPs) are essential regulators of skeletal homeostasis, and BMP9 is the most potently osteogenic among them. Here, we found that BMP9 and BMP2 rapidly induced early growth response 1 (EGR1) protein expression in osteoblas
Autor:
Tetsuya Matsuguchi, Kenjiro Bandow, Tomokazu Ohnishi, Kaori Shima, Joji Kusuyama, Muhammad Subhan Amir, Ichiro Semba
Publikováno v:
Biochemical Journal. 476:3533-3548
Hypoxia in adipose tissue is regarded as a trigger that induces dysregulation of the secretory profile in adipocytes. Similarly, local dysregulation of adipocytokine secretion is an initial event in the deleterious effects of obesity on metabolism. W
Autor:
Brent G. Albertson, Kenjiro Bandow, Muhammad Subhan Amir, Kaori Shima, Toshiaki Nakamura, Joji Kusuyama, Kazuyuki Noguchi, Tetsuya Matsuguchi, Ichiro Semba, Tomokazu Ohnishi
Publikováno v:
The FASEB Journal. 33:7331-7347
Osteoblasts are versatile cells involved in multiple whole-body processes, including bone formation and immune response. Secretory amounts and patterns of osteoblast-derived proteins such as osteopontin (OPN) and osteocalcin (OCN) modulate osteoblast
Autor:
Michelle R Sukup-Jackson, Orsolya Kiraly, Jennifer E Kay, Li Na, Elizabeth A Rowland, Kelly E Winther, Danielle N Chow, Takafumi Kimoto, Tetsuya Matsuguchi, Vidya S Jonnalagadda, Vilena I Maklakova, Vijay R Singh, Dushan N Wadduwage, Jagath Rajapakse, Peter T C So, Lara S Collier, Bevin P Engelward
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004299 (2014)
Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or environmental conditions that either suppress or induce HR cause genomic instability. Despite
Externí odkaz:
https://doaj.org/article/2decdde047414682a537adc4b06d89d3