Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Tetsuya, Kamataki"'
Autor:
Ryo Takata, Tetsuya Kamataki, Go Kito, Yasuhiro Uno, Toyomasa Katagiri, Kazuko Nakagawa, Hiroshi Yamazaki, Yusuke Nakamura
Publikováno v:
Drug Metabolism and Pharmacokinetics. 32:100-107
Sex and age differences in hepatic expression of drug-metabolizing enzyme genes could cause variations in drug metabolism, but has not been fully elucidated, especially in Asian population. In this study, the global expression of human hepatic genes
Publikováno v:
Journal of Cancer Therapy. :29-35
Recent genome-wide association studies have identified several lung cancer susceptibility loci. We previously carried out a replication study in male Japanese smokers that focused on chromosome 5p15 (telomerase reverse transcriptase) and 3q28 (tumor
Autor:
Mitsuhiko Osaki, Kaoru Kobayashi, Hiroshi Yamazaki, Shoko Takehara, Masaharu Akita, Kanako Kazuki, Satoshi Abe, Daisuke Satoh, Ryo Ohta, Yasuhiro Kazuki, Tetsuya Kamataki, Mitsuo Oshimura
Publikováno v:
Scientific Reports
Thalidomide is a teratogen in humans but not in rodents. It causes multiple birth defects including malformations of limbs, ears, and other organs. However, the species-specific mechanism of thalidomide teratogenicity is not completely understood. Re
Autor:
Hiroshi Yamazaki, Tatsuya Takeshita, Shunsuke Iwano, Hideki Ishikawa, Masaki Fujieda, Kazuma Kiyotani, Tetsuya Kamataki, Asami Muroi
Publikováno v:
Journal of Cancer Therapy. :207-215
Tobacco smoking is a risk factor for colorectal cancer and adenomas. To clarify the effect of genetic factors on the risk for tobacco-related colorectal tumors in a Japanese population, we performed a case-control study on 300 patients with two or mo
Publikováno v:
Journal of Cancer Therapy. :690-696
Recent genome-wide association studies have identified lung cancer susceptibility loci, such as chromosome 5p15 (telomerase reverse transcriptase, TERT and cleft lip and palate transmembrane protein 1-like, CLPTM1L), 15q25 (nicotinic cholinergic rece
Autor:
Hiroshi Yamazaki, Shunsuke Iwano, Norihito Shibahara, Tetsuya Kamataki, Yuiko Masunaga, Kazuma Kiyotani
Publikováno v:
Drug Metabolism and Pharmacokinetics. 26:451-457
Summary: Cytochrome P450 (CYP) 1A1 is involved in the metabolic activation of polycyclic aromatic hydrocarbons (PAHs) and is induced by several compounds, including PAHs. The induction of CYP1A1 mediated by the aryl hydrocarbon receptor (AhR) has bee
Autor:
Taku Nagano, Norie Murayama, Hiroshi Yamazaki, Ryohji Takano, Fumiaki Shono, Tetsuya Kamataki, Kazuma Kiyotani, Makiko Shimizu
Publikováno v:
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health; Volume 7; Issue 7; Pages: 2953-2964
International Journal of Environmental Research and Public Health, Vol 7, Iss 7, Pp 2953-2964 (2010)
International Journal of Environmental Research and Public Health; Volume 7; Issue 7; Pages: 2953-2964
International Journal of Environmental Research and Public Health, Vol 7, Iss 7, Pp 2953-2964 (2010)
Human biomonitoring of plasma and urinary levels of nicotine, cotinine, and 3′-hydroxycotinine was conducted after daily cigarette smoking in a population of 92 male Japanese smokers with a mean age of 37 years who had smoked an average of 23 cigar
Autor:
Koshiro Itahashi, Mitsukazu Kitada, Yuko Okajima, Yoriko Ota, Hiroyoshi Takamizawa, I. Fukazawa, Noriyuki Inaba, Tetsuya Kamataki, Naomi Sato, Yasuo Hirai, Giichi Yamamoto
Publikováno v:
Asia-Oceania Journal of Obstetrics and Gynaecology. 19:329-341
Cytochrome P-450 of human fetal livers (P-450HFLa) was demonstrated by the avidin-biotin immunoperoxidase technique in tissue samples as follows: human fetal organs, adult livers, human and cynomolgus placenta, and gynecologic organs which were obtai
Autor:
Ryoji Masui, Paul E. Cizdziel, Yasushi Kogo, Kazuma Kiyotani, Hiroshi Shimada, Masami Murakami, Yuki Kawai, Yasumasa Mitani, Seiki Kuramitsu, Kanako Hoshi, Toru Miyagi, Katsuhiko Tsunekawa, Hideki Takakura, Kazuhiro Shibata, Yoshihide Hayashizaki, Kenji Fukui, Takeshi Kikuchi, Chiaki Kato, Takahiro Arakawa, Alexander Lezhava, Alistair M. Chalk, Tetsuya Kamataki, Masayoshi Itoh, Takanori Oka, Atsuko Oguchi-Katayama
Publikováno v:
Nature Methods. 4:257-262
We developed a rapid single nucleotide polymorphism (SNP) detection system named smart amplification process version 2 (SMAP 2). Because DNA amplification only occurred with a perfect primer match, amplification alone was sufficient to identify the t
Publikováno v:
Xenobiotica. 37:30-43
The monkey is often used to predict metabolism of drugs in humans since it generally shows a metabolic pattern similar to humans. However, metabolic profiles different from humans are occasionally seen in monkeys for some drugs including pitavastatin