Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tetsushi Kawahara"'
Autor:
Jiro Hirose, Masaki Nakamura, Shoji Furusako, Tetsushi Kawahara, Yoshitaka Hosaka, Takashi Takeuchi, Kazuyuki Nakayama
Publikováno v:
European journal of pharmacology. 802
Severe sepsis is a complex, multifactorial, and rapidly progressing disease characterized by excessive inflammation and coagulation following bacterial infection. To simultaneously suppress pro-inflammatory and pro-coagulant responses, we genetically
Publikováno v:
Journal of Biological Chemistry. 273:9912-9920
When unfolded proteins are accumulated in the endoplasmic reticulum (ER), an intracellular signaling pathway termed the unfolded protein response (UPR) is activated to induce transcription of ER-localized molecular chaperones and folding enzymes in t
Publikováno v:
Journal of Biological Chemistry. 273:1802-1807
Accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates an intracellular signaling pathway from the ER to the nucleus, termed the unfolded protein response. We and others recently identified transcription factor Hac1p/Ern4p resp
Autor:
Tetsushi Kawahara, Yukiko Yatagai, Yoshitaka Hosaka, Mikihiko Shinozaki, Motoyasu Honda, Shoji Furusako, Hiroshi Takayama, Kazuyuki Nakayama, Tooru Yokoyama, Tomokazu Matsusue, Michiru Kurihara, Katsuki Naitoh, Jiro Hirose, Kamon Shirakawa
Publikováno v:
The Journal of clinical investigation. 118(5)
Platelet adhesion to vascular subendothelium, mediated in part by interactions between collagen and glycoprotein VI (GPVI) complexed with Fc receptor gamma-chain, is crucial for thrombus formation. Antiplatelet therapy benefits patients with various
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(9)
Eukaryotic cells control the levels of molecular chaperones and folding enzymes in the endoplasmic reticulum (ER) by a transcriptional induction process termed the unfolded protein response (UPR) according to the needs within the ER. In Saccharomyces
Publikováno v:
Molecular biology of the cell. 8(10)
An intracellular signaling from the endoplasmic reticulum (ER) to the nucleus, called the unfolded protein response (UPR), is activated when unfolded proteins are accumulated in the ER under a variety of stress conditions (“ER stress”). We and ot
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 1(9)
Background: Accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the transcriptional induction of molecular chaperones and folding enzymes localized in the ER. Thus, eukaryotic cells possess an intracellular signalling pathway
Autor:
Yoshitaka Hosaka, Syouji Furusako, Yasuko Araki, Kazuyuki Nakayama, Takashi Takeuchi, Tetsushi Kawahara, Masaki Nakamura, Tamami Oono
Publikováno v:
Critical Care Medicine. 34:A45
Autor:
Shoji Furusako, Yoshitaka Hosaka, Hiroshi Takayama, Motoyasu Honda, Kazuyuki Nakayama, Toru Yamakawa, Tetsushi Kawahara, Mikihiko Shinozaki, Katsuki Naitoh, Kamon Shirakawa
Publikováno v:
Blood. 106:2168-2168
The first reported patient with platelet GPVI deficiency (Blood1987;69:1712) had anti-GPVI antibodies (YA-Abs) in the patient’s serum, which contributed to later progress in identification of GPVI as a novel collagen receptor. Although there is now
Autor:
Masaki Nakamura1 mnakamur@mochida.co.jp, Takashi Takeuchi1, Tetsushi Kawahara1, Jiro Hirose1, Kazuyuki Nakayama1, Yoshitaka Hosaka1, Shoji Furusako1
Publikováno v:
European Journal of Pharmacology. May2017, Vol. 802, p60-68. 9p.