Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Tetsushi Iwasaki"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Cellular senescence is defined as irreversible growth arrest induced by various stress, such as DNA damage and oxidative stress. Senescent cells exhibit various characteristic morphological changes including enlarged morphology. In our recen
Externí odkaz:
https://doaj.org/article/29318c9ac0144953bd14b72dff83a2a5
Autor:
Yuki Yoshikawa, Keisuke Yuzu, Naoki Yamamoto, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Tetsushi Iwasaki, Masatomo So, Yuji Goto, Atsuo Tamura, Eri Chatani
Publikováno v:
Molecules, Vol 27, Iss 13, p 3964 (2022)
Amyloid fibrils have been an important subject as they are involved in the development of many amyloidoses and neurodegenerative diseases. The formation of amyloid fibrils is typically initiated by nucleation, whereas its exact mechanisms are largely
Externí odkaz:
https://doaj.org/article/38b66ab5c6674483a5ad5271480a0da0
Autor:
Shigeru Kihira, Junpei Yoshida, Yukari Kawada, Yuriko Hitomi, Tomohisa Asada, Rie Hisatomi, Akina Ohta, Tetsushi Iwasaki, A. K. M. Mahbub Hasan, Yasuo Fukami, Ken-ichi Sato
Publikováno v:
Biology Open, Vol 1, Iss 10, Pp 1024-1034 (2012)
Summary Our previous study demonstrated that tyrosine phosphorylation of p145met/β-subunit of hepatocyte growth factor receptor by epidermal growth factor receptor and Src contributes to the anti-apoptotic growth of human bladder carcinoma cell 5637
Externí odkaz:
https://doaj.org/article/6b66996349fb44868e835ef3c4e1763d
Autor:
Keisuke Yuzu, Masatomo So, Yuji Goto, Eri Chatani, Tetsushi Iwasaki, Naoki Yamamoto, Masahiro Noji, Motonari Tsubaki
Publikováno v:
Biophys J
Amyloid fibrils are aberrant protein aggregates associated with various amyloidoses and neurodegenerative diseases. It is recently indicated that structural diversity of amyloid fibrils often results in different pathological phenotypes, including cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea3a03ff00c672e4e26a3d30e74dceb
https://doi.org/10.1016/j.bpj.2020.12.005
https://doi.org/10.1016/j.bpj.2020.12.005
Autor:
Watson P. Folk, Alpana Kumari, Tetsushi Iwasaki, Erica K. Cassimere, Slovénie Pyndiah, Elizabeth Martin, Kelly Homlar, Daitoku Sakamuro
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13324
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 13324, p 13324 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 13324, p 13324 (2021)
The pro-apoptotic tumor suppressor BIN1 inhibits the activities of the neoplastic transcription factor MYC, poly (ADP-ribose) polymerase-1 (PARP1), and ATM Ser/Thr kinase (ATM) by separate mechanisms. Although BIN1 deficits increase cancer-cell resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f993e8b19e5984434f30e687837027
Autor:
Kousuke Akino, Alexander A. Tokmakov, Ken-ichi Sato, Sho Iguchi, Vasily Stefanov, Tetsushi Iwasaki
Publikováno v:
Biochemical and Biophysical Research Communications. 517:140-145
Mitogen-activated protein kinases (MAPKs) are involved in the regulation of various cellular processes, including cell survival and apoptosis. Here, we report that Xenopus p42 MAPK becomes phosphorylated in apoptotic eggs, however this modification d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbb9d975ef0cca9726008994396451a
https://doi.org/10.1016/j.bbrc.2019.07.033
https://doi.org/10.1016/j.bbrc.2019.07.033
Autor:
Slovénie Pyndiah, Daitoku Sakamuro, Amy L. Abdulovic-Cui, Erica K. Cassimere, Watson P. Folk, Joanna C. Johnson, Alpana Kumari, Tetsushi Iwasaki
Publikováno v:
Journal of Biological Chemistry. 294:5700-5719
The tumor suppressor bridging integrator 1 (BIN1) is a corepressor of the transcription factor E2F1 and inhibits cell-cycle progression. BIN1 also curbs cellular poly(ADP-ribosyl)ation (PARylation) and increases sensitivity of cancer cells to DNA-dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc1b8a621d24543d04160e380092cf5
https://doi.org/10.1074/jbc.ra118.005699
https://doi.org/10.1074/jbc.ra118.005699
Autor:
Taiki Nagano, Shinji Kamada, Tetsushi Iwasaki, Shione Kuwaba, Kentaro Mio, Taiichi Osumi, Yuto Awai
Publikováno v:
Molecular Biology of the Cell
Cellular senescence is a state of permanent proliferative arrest induced by a variety of stresses, such as DNA damage. The transcriptional activity of p53 has been known to be essential for senescence induction. It remains unknown, however, whether a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693f904ad4847c12f93b8afa5f5e352c
http://europepmc.org/articles/PMC8693961
http://europepmc.org/articles/PMC8693961
Autor:
Keisuke Yuzu, Naoki Yamamoto, Masahiro Noji, Yuji Goto, Motonari Tsubaki, Masatomo So, Tetsushi Iwasaki, Eri Chatani
Amyloid fibrils are aberrant protein aggregates associated with various amyloidoses and neurodegenerative diseases. It is recently indicated that structural diversity of amyloid fibrils often results in different pathological phenotypes including cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af0ec827bdd9c8534add9758acc2e1e
https://doi.org/10.1101/2020.07.19.211284
https://doi.org/10.1101/2020.07.19.211284
Publikováno v:
FEBS Letters. 592(19):3327-3334
The MEKK1 kinase is a key regulator of stress signaling in Arabidopsis; however, little is known about the regulation of its kinase activity. Here, we found that recombinant MEKK1, expressed in both mammalian HEK293 cells and Escherichia coli, shows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341cc5a165ed7979d955c0db8b38ffe3
https://hdl.handle.net/20.500.14094/90006401
https://hdl.handle.net/20.500.14094/90006401