Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tetsuro Kusab"'
Autor:
Aya Tomita-Yagi, Natsuko Ozeki-Okuno, Noriko Watanabe-Uehara, Kazumi Komaki, Minato Umehara, Hiroko Sawada-Yamauchi, Atsushi Minamida, Yasuto Sunahara, Yayoi Matoba, Itaru Nakamura, Tomohiro Nakata, Kunihiro Nakai, Tomoharu Ida, Noriyuki Yamashita, Michitsugu Kamezaki, Yuhei Kirita, Takuya Taniguchi, Eiichi Konishi, Satoaki Matoba, Keiichi Tamagaki, Tetsuro Kusaba
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109020- (2024)
Summary: The immense public health burden of diabetic kidney disease (DKD) has led to an increase in research on the pathophysiology of advanced DKD. The present study focused on the significance of proinflammatory vascular cell adhesion molecule 1 (
Externí odkaz:
https://doaj.org/article/36c4acbd72a24e17bffdbd9bb2527401
Autor:
Kunihiro Nakai, Minato Umehara, Atsushi Minamida, Hiroko Yamauchi-Sawada, Yasuto Sunahara, Yayoi Matoba, Natsuko Okuno-Ozeki, Itaru Nakamura, Tomohiro Nakata, Aya Yagi-Tomita, Noriko Uehara-Watanabe, Tomoharu Ida, Noriyuki Yamashita, Michitsugu Kamezaki, Yuhei Kirita, Eiichi Konishi, Hiroaki Yasuda, Satoaki Matoba, Keiichi Tamagaki, Tetsuro Kusaba
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Streptozotocin (STZ), an anti-cancer drug that is primarily used to treat neuroendocrine tumors (NETs) in clinical settings, is incorporated into pancreatic β-cells or proximal tubular epithelial cells through the glucose transporter, GLUT2
Externí odkaz:
https://doaj.org/article/c6fc859faa8f41899a7a45583febdea3
Autor:
Kunihiro Nakai, Hiroyoshi Segawa, Masatomo Yashiro, Kengo Yoshii, Tetsuro Kusaba, Satoaki Matoba, Keiichi Tamagaki, Tsuguru Hatta, Hiroshi Kado
Publikováno v:
Kidney and Dialysis, Vol 2, Iss 3, Pp 474-481 (2022)
A discrepancy between serum concentrations of cystatin C (CysC) and creatinine (sCr) has been reported in patients with acute obstructive nephropathy. However, the usefulness of CysC for predicting the recovery of kidney function in patients with sev
Externí odkaz:
https://doaj.org/article/02882c81edf2447da898cbdfc76c86fe
Autor:
Keiko Tanimura, Tadaaki Yamada, Koutaroh Okada, Kunihiro Nakai, Mano Horinaka, Yuki Katayama, Kenji Morimoto, Yuri Ogura, Takayuki Takeda, Shinsuke Shiotsu, Kosuke Ichikawa, Satoshi Watanabe, Yoshie Morimoto, Masahiro Iwasaku, Yoshiko Kaneko, Junji Uchino, Hirokazu Taniguchi, Kazue Yoneda, Satoaki Matoba, Toshiyuki Sakai, Hisanori Uehara, Seiji Yano, Tetsuro Kusaba, Ryohei Katayama, Koichi Takayama
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-12 (2022)
Abstract Anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) have shown dramatic efficacy in patients with ALK-rearranged lung cancer; however, complete response in these patients is rare. Here, we investigated the molecular mechanisms u
Externí odkaz:
https://doaj.org/article/22d87946d66b4cc0afe194c4ecc063ef
Autor:
Noriko Uehara-Watanabe, Natsuko Okuno-Ozeki, Atsushi Minamida, Itaru Nakamura, Tomohiro Nakata, Kunihiro Nakai, Aya Yagi-Tomita, Tomoharu Ida, Kisho Ikeda, Takashi Kitani, Noriyuki Yamashita, Michitsugu Kamezaki, Yuhei Kirita, Satoaki Matoba, Keiichi Tamagaki, Tetsuro Kusaba
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Kidney hypertrophy is a common clinical feature in patients with diabetes and is associated with poor renal outcomes. Initial cell proliferation followed by cellular hypertrophy are considered the responsible mechanisms for diabetic kidney h
Externí odkaz:
https://doaj.org/article/ca8c7780378f427c8cad82405155d8af
Autor:
Noriyuki Yamashita, Kunihiro Nakai, Tomohiro Nakata, Itaru Nakamura, Yuhei Kirita, Satoaki Matoba, Benjamin D. Humphreys, Keiichi Tamagaki, Tetsuro Kusaba
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Cisplatin is a commonly used anticancer drug, but nephrotoxicity is a dose-limiting adverse effect. Recent experimental and clinical observations have demonstrated that multiple injections of cisplatin induce the transition to chronic kidney
Externí odkaz:
https://doaj.org/article/b3d2333dacdc44cda4616a88f2d66a46
Autor:
Yusuke Hori, Tomoya Kitani, Kenji Yanishi, Takaomi Suga, Masaya Kogure, Tetsuro Kusaba, Yoshihiro Kushida, Mari Dezawa, Satoaki Matoba
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Cell-based therapies hold great promise for the treatment of peripheral arterial disease (PAD), especially in patients presenting with severe limb ischemia, although the optimal strategy remains to be explored. In this study, we evaluated the therape
Externí odkaz:
https://doaj.org/article/f7c2a9285b4a4fdd93fea74dd1b056c6
Autor:
Noriko Uehara-Watanabe, Natsuko Okuno-Ozeki, Itaru Nakamura, Tomohiro Nakata, Kunihiro Nakai, Aya Yagi-Tomita, Tomoharu Ida, Noriyuki Yamashita, Michitsugu Kamezaki, Yuhei Kirita, Satoaki Matoba, Keiichi Tamagaki, Tetsuro Kusaba
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10615- (2022)
Based on recent clinical trials using sodium-glucose co-transporter 2 inhibitor (SGLT2i) demonstrating the significant improvement of outcomes of diabetic kidney disease (DKD), the paradigm shift from “glomerulocentric” to “tubule centric” pa
Externí odkaz:
https://doaj.org/article/47b540a748dd4ea087fb68a7a2ac23b5
Autor:
Yuka Segawa, Ryo Ishida, Fuminao Kanehisa, Kunihiro Nakai, Mari Morimoto, Masafumi Seno, Mayuka Nakayama, Tetsuro Kusaba, Norito Katoh, Keiichi Tamagaki
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-6 (2020)
Abstract Background IgA nephropathy is the most common glomerulonephritis. Secondary IgA nephropathy complicated with systemic diseases, including psoriasis, is also often reported. Generalized pustular psoriasis is a form of psoriasis characterized
Externí odkaz:
https://doaj.org/article/8af8c30bc1824b4e9d9a29692a3f94a4
Autor:
Masayuki Hara, Yoichi Minami, Munehiro Ohashi, Yoshiki Tsuchiya, Tetsuro Kusaba, Keiichi Tamagaki, Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, Kazuhiro Yagita
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Circadian clocks in mammals function in most organs and tissues throughout the body. Various renal functions such as the glomerular filtration and excretion of electrolytes exhibit circadian rhythms. Although it has been reported that the ex
Externí odkaz:
https://doaj.org/article/69b90a5eabb74e1db275fed1e4d32f50