Zobrazeno 1 - 10
of 808
pro vyhledávání: '"Tetsuro KOBAYASHI"'
Autor:
Motoi Yamashita, Chihiro Ogawa, Baihao Zhang, Tetsuro Kobayashi, Aneela Nomura, Clive Barker, Chengcheng Zou, Satoshi Yamanaka, Ken-ichiro Hayashi, Yoichi Shinkai, Kazuyo Moro, Sidonia Fargarasan, Koshi Imami, Jun Seita, Fumiyuki Shirai, Tatsuya Sawasaki, Masato T. Kanemaki, Ichiro Taniuchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Despite its broad application in in vitro studies, the application of targeted protein degradation (TPD) to animal models faces considerable challenges. Here, we develop inducible and cell-type specific TPD systems in mice using two degron s
Externí odkaz:
https://doaj.org/article/25c223a99b6c459b9d22b8d5fd64d60c
Autor:
Eiji Kawasaki, Takuya Awata, Hiroshi Ikegami, Akihisa Imagawa, Yoichi Oikawa, Haruhiko Osawa, Takeshi Katsuki, Norio Kanatsuna, Ryoichi Kawamura, Junji Kozawa, Noriko Kodani, Tetsuro Kobayashi, Akira Shimada, Masayuki Shimoda, Kazuma Takahashi, Daisuke Chujo, Tetsuro Tsujimoto, Kyoichiro Tsuchiya, Aiko Terakawa, Jungo Terasaki, Kan Nagasawa, Shinsuke Noso, Tomoyasu Fukui, Ichiro Horie, Kazuki Yasuda, Hisafumi Yasuda, Hidekatsu Yanai, Toshiaki Hanafusa, Hiroshi Kajio, the Japanese Type 1 Diabetes Database Study (TIDE‐J)
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 7, Pp 835-842 (2024)
Abstract Aims/Introduction This study aimed to identify risk factors that contribute to the progression of slowly‐progressive type 1 diabetes by evaluating the positive predictive value (PPV) of factors associated with the progression to an insulin
Externí odkaz:
https://doaj.org/article/2548a80a84c24af5abc976218388891e
Autor:
Kaoru Nagasawa, Kimio Matsumura, Takayasu Uchida, Yuya Suzuki, Akihiro Nishimura, Minoru Okubo, Yukifusa Igeta, Tetsuro Kobayashi, Takashi Sakurai, Yasumichi Mori
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 7, Pp 922-930 (2024)
Abstract Aims/Introduction This study aimed to characterize the global cognition and executive functions of older adults with type 1 diabetes mellitus in comparison with type 2 diabetes mellitus. Materials and Methods This study included 37 patients
Externí odkaz:
https://doaj.org/article/aae7a3210d9a4cdeb2a26aadfafa6952
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Japan implemented its nationwide vaccination program against COVID-19 in 2021, immunizing more than one million people (approximately 1%) a day. However, the direct and indirect impacts of the program at the population level have yet to be f
Externí odkaz:
https://doaj.org/article/80f0e26f077e458a948854c697edc4e5
Autor:
Nobuaki Takehana, Tomoyasu Fukui, Yusaku Mori, Munenori Hiromura, Michishige Terasaki, Makoto Ohara, Michiya Takada, Masako Tomoyasu, Yoshihisa Ito, Tetsuro Kobayashi, Sho‐ichi Yamagishi
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 7, Pp 856-863 (2023)
Abstract Aims/Introduction This study aimed to compare the positivity rates of glutamic acid decarboxylase autoantibodies (GADA) and ElisaRSR™ 3 Screen ICA™ (3 Screen ICA), a newly developed assay for the simultaneous measurement of GADA, insulin
Externí odkaz:
https://doaj.org/article/ccf155f05aba41eeaa310a9ea7bbecf1
Publikováno v:
New Microbes and New Infections, Vol 56, Iss , Pp 101214- (2024)
Background: A highly pathogenic avian influenza (HPAI) A (H5N1) virus has been detected in domestic and wild animals worldwide. The incidence of HPAI infections in sea mammals has been increasing, as is the number of stranded marine mammals linked to
Externí odkaz:
https://doaj.org/article/e3d310d4c17246ccba1fa44a6ff1fa76
Autor:
Tomoyasu Fukui, Tetsuro Kobayashi, Erika Jimbo, Kaoru Aida, Akira Shimada, Yoichi Oikawa, Yasumichi Mori, Takeshi Fujii, Rikako Koyama, Kazuhiko Kobayashi, Akira Takeshita, Soroku Yagihashi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract In slowly progressive type 1 diabetes mellitus (SPIDDM), the pancreas shows sustained islet inflammation, pancreatitis, pancreatic acinar cell metaplasia/dysplasia (ADM), and intraepithelial neoplasia (PanIN), a precancerous lesion. The mech
Externí odkaz:
https://doaj.org/article/192035497fce47b4ae7ddaa4acd591c0
Autor:
Eiji Kawasaki, Akira Shimada, Akihisa Imagawa, Norio Abiru, Takuya Awata, Yoichi Oikawa, Haruhiko Osawa, Yumiko Kawabata, Junji Kozawa, Tetsuro Kobayashi, Kazuma Takahashi, Daisuke Chujo, Tomoyasu Fukui, Junnosuke Miura, Kazuki Yasuda, Hisafumi Yasuda, Hiroshi Kajio, Toshiaki Hanafusa, Hiroshi Ikegami, the Committee of type 1 diabetes, Japan Diabetes Society
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 4, Pp 570-581 (2023)
Abstract Aim/Introduction To investigate the differences in the clinical significance and glutamic acid decarboxylase autoantibody (GADA) affinity between RIA (RIA‐GADA) and ELISA (ELISA‐GADA) in patients with type 1 diabetes. Methods A total of
Externí odkaz:
https://doaj.org/article/2a9fa9ca920b4a4e95c71e26da6c0a9c
Autor:
Eiji Kawasaki, Akira Shimada, Akihisa Imagawa, Norio Abiru, Takuya Awata, Yoichi Oikawa, Haruhiko Osawa, Yumiko Kawabata, Junji Kozawa, Tetsuro Kobayashi, Kazuma Takahashi, Daisuke Chujo, Tomoyasu Fukui, Junnosuke Miura, Kazuki Yasuda, Hisafumi Yasuda, Hiroshi Kajio, Toshiaki Hanafusa, Hiroshi Ikegami, the Committee of type 1 diabetes, Japan Diabetes Society
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 1, Pp 58-66 (2023)
Abstract Aims/Introduction This study aimed to investigate the clinical significance and antigen specificity of autoantibodies to insulinoma‐associated antigen‐2 (IA‐2A) by radioimmunoassay (RIA; IA‐2A‐RIA) and enzyme‐linked immunosorbent
Externí odkaz:
https://doaj.org/article/b5d09b3b2ef946e3ad57d361fe587d35
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 12, Pp 13137-13151 (2022)
The basic reproduction number, $ R_0 $, plays a central role in measuring the transmissibility of an infectious disease, and it thus acts as the fundamental index for planning control strategies. In the present study, we apply a branching process mod
Externí odkaz:
https://doaj.org/article/3aef40efeb9140eb979993ca6a79af81