Zobrazeno 1 - 10
of 424
pro vyhledávání: '"Tetsuro Hirose"'
Autor:
Sakura Hiramatsu, Ryo Ataka, Yusuke Nakayama, Miho Hirai, Ayako Hirata, Jun Takeshima, Kenjiro Hirai, Shinya Hamasu, Ikuo Aoyama, Tetsuro Hirose
Publikováno v:
Surgical Case Reports, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Inflammatory myofibroblastic tumor (IMT) is a rare stromal tumor, often found in children and young adults, and most commonly occurs in the lungs. Surgical resection is considered the standard treatment for localized IMT, although
Externí odkaz:
https://doaj.org/article/83d2d46fabf84c8781fab74a2861f859
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Liquid-liquid phase separation (LLPS) has been thought to be the biophysical principle governing the assembly of the multiphase structures of nucleoli, the site of ribosomal biogenesis. Condensates assembled through LLPS increase their sizes
Externí odkaz:
https://doaj.org/article/8ebec638e73042cea5256fa37ae71f7b
Autor:
Kazuhiro Fukumura, Rei Yoshimoto, Luca Sperotto, Hyun-Seo Kang, Tetsuro Hirose, Kunio Inoue, Michael Sattler, Akila Mayeda
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The length distribution of human pre-mRNA introns is very extensive. The authors demonstrate that splicing in a subset of short introns is dependent on SPF45 (RBM17), which replaces authentic U2AF-heterodimer on the truncated poly-pyrimidine tracts a
Externí odkaz:
https://doaj.org/article/9ab44e7770a74812b0cfe956d0384151
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Paraspeckles are nuclear bodies scaffolded by RNP complexes of NEAT1_2 RNA transcripts and multiple RNA-binding proteins. The assembly of paraspeckles is coupled with the transcription of NEAT1_2. Paraspeckles form the core-shell structure, where the
Externí odkaz:
https://doaj.org/article/bc3a51a39cdf4f7babdb083e67b78cd1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Phase separation is a fundamental mechanism for compartmentalization in cells and leads to the formation of biomolecular condensates, generally containing various RNA molecules. RNAs are biomolecules that can serve as suitable scaffolds for biomolecu
Externí odkaz:
https://doaj.org/article/c393e9ac885142dbb66ae662665ca267
Autor:
Azam, Sikandar, Armijo, Kaitlyn S., Weindel, Chi G., Chapman, Morgan J., Devigne, Alice, Shinichi Nakagawa, Tetsuro Hirose, Carpenter, Susan, Watson, Robert O., Patrick, Kristin L.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/27/2024, Vol. 121 Issue 9, p1-12, 35p
Autor:
Tomonori Shibata, Konami Nagano, Morio Ueyama, Kensuke Ninomiya, Tetsuro Hirose, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, Kazuhiko Nakatani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Synthetic small molecules modulating RNA structure and function have therapeutic potential for RNA diseases. Here the authors show the mechanism by which a small molecule targets the disease-causing r(UGGAA) n repeat RNAs in spinocerebellar ataxia ty
Externí odkaz:
https://doaj.org/article/fb74152ab4824a57b44c57a7b829b312
Autor:
Martina Gast, Vanasa Nageswaran, Andreas W. Kuss, Ana Tzvetkova, Xiaomin Wang, Liliana H. Mochmann, Pegah Ramezani Rad, Stefan Weiss, Stefan Simm, Tanja Zeller, Henry Voelzke, Wolfgang Hoffmann, Uwe Völker, Stefan B. Felix, Marcus Dörr, Antje Beling, Carsten Skurk, David-Manuel Leistner, Bernhard H. Rauch, Tetsuro Hirose, Bettina Heidecker, Karin Klingel, Shinichi Nakagawa, Wolfram C. Poller, Filip K. Swirski, Arash Haghikia, Wolfgang Poller
Publikováno v:
Cells, Vol 11, Iss 24, p 3970 (2022)
The evolutionary conserved NEAT1-MALAT1 gene cluster generates large noncoding transcripts remaining nuclear, while tRNA-like transcripts (mascRNA, menRNA) enzymatically generated from these precursors translocate to the cytosol. Whereas functions ha
Externí odkaz:
https://doaj.org/article/ec8ff563749948efa86a683c898e23a4
Autor:
Keita Yamamoto, Susumu Goyama, Shuhei Asada, Takeshi Fujino, Taishi Yonezawa, Naru Sato, Reina Takeda, Akiho Tsuchiya, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Hikaru Toya, Ayana Kon, Yasuhito Nannya, Rena Onoguchi-Mizutani, Shinichi Nakagawa, Tetsuro Hirose, Seishi Ogawa, Nobuyoshi Akimitsu, Toshio Kitamura
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109576- (2021)
Summary: Paraspeckles are membraneless organelles formed through liquid-liquid phase separation and consist of multiple proteins and RNAs, including NONO, SFPQ, and NEAT1. The role of paraspeckles and the component NONO in hematopoiesis remains unkno
Externí odkaz:
https://doaj.org/article/51f0dc93f4604f38953cd945fbc72291
Autor:
Takumi Kozu, Tatsuo Ito, Ryo Ataka, Ryo Taga, Jun Matsubayashi, Yusuke Nakayama, Yoshinobu Ikeno, Kazuhiko Kitaguchi, Eiji Toyoda, Tetsuro Hirose
Publikováno v:
The Japanese Journal of Gastroenterological Surgery. 56:34-41