Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tetsuo Yamagishi"'
Autor:
Tetsuo Yamagishi, Sumit Sahni, Akanksha Arvind, Danae M. Sharp, Patric J. Jansson, Des R. Richardson
Publikováno v:
Journal of Biological Chemistry. 288:31761-31771
Localization of the drug transporter P-glycoprotein (Pgp) to the plasma membrane is thought to be the only contributor of Pgp-mediated multidrug resistance (MDR). However, very little work has focused on the contribution of Pgp expressed in intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b32c91ccfac386d7cd03ffa1ee3dbd
https://doi.org/10.1074/jbc.m113.514091
https://doi.org/10.1074/jbc.m113.514091
Autor:
Jia Li, Yuling Chen, Karieshma Kabani, Tetsuo Yamagishi, Warren Kaplan, Daniel Man-Yuen Sze, Ross D. Brown, Suilin Mo, Mark J. Cowley, Yen Siew Loh, P. Joy Ho, Shihong Yang, Douglas E. Joshua, Esther Aklilu
Publikováno v:
Blood. 115:3580-3588
T cells contribute to host-tumor interactions in patients with monoclonal gammopathies. Expansions of CD8+CD57+ T-cell receptor Vβ–positive (TCRVβ+)–restricted cytotoxic T-cell (CTL) clones are found in 48% of patients with multiple myeloma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42452d21c858f19fa1660cd1c2bf4c4
https://doi.org/10.1182/blood-2009-10-246991
https://doi.org/10.1182/blood-2009-10-246991
Autor:
Tetsuo Yamagishi, Des R. Richardson, Egarit Noulsri, Danuta S. Kalinowski, Kovit Pattanapanyasat, Surada Lerdwana, Suthat Fucharoen
Publikováno v:
American Journal of Hematology. 84:170-176
Iron chelators have been reported to induce apoptosis and cell cycle arrest in cancer cells. Recent studies suggest broad and selective antitumor activity of the new iron chelator, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT; Whitnall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003c6ca7770f31acb34ec84a8258886d
https://doi.org/10.1002/ajh.21350
https://doi.org/10.1002/ajh.21350
Autor:
Tetsuo Yamagishi, Shihong Yang, Douglas E. Joshua, Suilin Mo, Basil D. Roufogalis, Daniel Man-Yuen Sze, Ross D. Brown, Yen Siew Loh
Publikováno v:
Leukemia & Lymphoma. 49:1813-1816
Multiple myeloma (MM) is an incurable B cell malignancy characterised by the accumulation of monoclonal plasma cells in the bone marrow and the presence of high level of monoclonal immunoglobulin i...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77096e7755bcc18d402a0cd693f2be92
https://doi.org/10.1080/10428190802272676
https://doi.org/10.1080/10428190802272676
Autor:
Danae M. Sharp, Alexandra E. Stacy, Sanaz Maleki, Des R. Richardson, Nicole A. Seebacher, Sumit Sahni, Tetsuo Yamagishi, Elaine Gutierrez, Akanksha Arvind, Patric J. Jansson
Publikováno v:
The Journal of biological chemistry. 290(15)
Background: There is a critical need for chemotherapeutics that overcome multidrug resistance (MDR). Results: Dp44mT is transported into the lysosome by Pgp, causing lysosomal targeting of Dp44mT and resulting in enhanced cytotoxicity in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d3b809b03c43433fd0404a5c4146e2
https://pubmed.ncbi.nlm.nih.gov/25720491
https://pubmed.ncbi.nlm.nih.gov/25720491
Publikováno v:
Molecular Cancer Therapeutics. 10:C40-C40
Introduction: Deprivation of cellular iron (Fe) may represent a novel and effective anti-cancer strategy1. Our laboratory has developed iron chelators with marked and selective anti-tumor activity against a variety of tumor types in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de893a1ba92712c78b992c4256dbf4b
https://doi.org/10.1158/1535-7163.targ-11-c40
https://doi.org/10.1158/1535-7163.targ-11-c40
Autor:
Shihong Yang, Yuling Chen, Douglas E. Joshua, Warren Kaplan, Karieshma Kabani, Daniel Sze, Suilin Mo, Esther Aklilu, Phoebe Joy Ho, Jia Li, Tetsuo Yamagishi, Ross D. Brown, Yen Siew Loh, Mark J. Cowley
Publikováno v:
Blood. 114:1820-1820
Abstract 1820 Poster Board I-846 T cells contribute to the immunomodulatory control of the tumor in patients with monoclonal gammopathies. We previously found that CD3+CD8+CD57+TCRVβ+restricted cytotoxic T cell expansions were present in 48% of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ae1f24a19011e8f30f8394cb724511
https://doi.org/10.1182/blood.v114.22.1820.1820
https://doi.org/10.1182/blood.v114.22.1820.1820
Autor:
Ross D. Brown, Warren Kaplan, Phoebe Joy Ho, John Gibson, Daniel Sze, Tetsuo Yamagishi, Douglas E. Joshua
Publikováno v:
Blood. 108:3395-3395
Previous studies have suggested that expanded T-cell clones are found in the blood of 59% of patients with multiple myeloma. These expanded T-cell clones are associated with prolonged overall survival and thus it has been suggested that they may have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff8513c4b38708298c33578ba706fd6
https://doi.org/10.1182/blood.v108.11.3395.3395
https://doi.org/10.1182/blood.v108.11.3395.3395
Autor:
Shihong Yang, Joy Ho, Devanshi Seth, Daniel M. Sze, Ross D. Brown, Xin An, Tetsuo Yamagishi, Douglas E. Joshua, Warren Kaplan, John Gibson
Publikováno v:
Blood. 106:3418-3418
Different stages of differentiation of CD8 T cells based on the expression of costimulatory receptors - CD28 and CD27 has been previously described (Nature Medicine8:379, 2002). Specifically, CD8 T cells that are CD28−CD27− are designated as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e8bc2f4374b70deb268358e5572e00
https://doi.org/10.1182/blood.v106.11.3418.3418
https://doi.org/10.1182/blood.v106.11.3418.3418