Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Tetsuo Nakajima"'
Autor:
Anne-Sophie Wozny, Gersende Alphonse, Audrey Cassard, Céline Malésys, Safa Louati, Michael Beuve, Philippe Lalle, Dominique Ardail, Tetsuo Nakajima, Claire Rodriguez-Lafrasse
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract DNA double-strand breaks (DSBs) induced by photon irradiation are the most deleterious damage for cancer cells and their efficient repair may contribute to radioresistance, particularly in hypoxic conditions. Carbon ions (C-ions) act indepen
Externí odkaz:
https://doaj.org/article/b9246a0bfb4742b4a947afac465121a4
Autor:
Bing Wang, Takanori Katsube, Kaoru Tanaka, Yasuharu Ninomiya, Hirokazu Hirakawa, Cuihua Liu, Kouichi Maruyama, Guillaume Varès, Seiji Kito, Tetsuo Nakajima, Akira Fujimori, Mitsuru Nenoi
Publikováno v:
Life, Vol 12, Iss 4, p 565 (2022)
Humans are exposed to both psychological stress (PS) and radiation in some scenarios such as manned deep-space missions. It is of great concern to verify possible enhanced deleterious effects from such concurrent exposure. Pioneer studies showed that
Externí odkaz:
https://doaj.org/article/622b53fe852b4e1fb169563e395c5d44
Autor:
Bing Wang, Kaoru Tanaka, Takanori Katsube, Kouichi Maruyama, Yasuharu Ninomiya, Guillaume Varès, Cuihua Liu, Hirokazu Hirakawa, Masahiro Murakami, Zeenath Fardous, Nahida Sultana, Kazuko Fujita, Akira Fujimori, Tetsuo Nakajima, Mitsuru Nenoi
Publikováno v:
Dose-Response, Vol 19 (2021)
Radioadaptive response (RAR) describes a phenomenon in a variety of in vitro and in vivo systems that a low-dose of priming ionizing radiation (IR) reduces detrimental effects of a subsequent challenge IR at higher doses. Among in vivo investigations
Externí odkaz:
https://doaj.org/article/03d8791947da4b3e8fadd3c11fa3aa4a
Autor:
Anne-Sophie Wozny, Arnaud Gauthier, Gersende Alphonse, Céline Malésys, Virginie Varoclier, Michael Beuve, Delphine Brichart-Vernos, Nicolas Magné, Nicolas Vial, Dominique Ardail, Tetsuo Nakajima, Claire Rodriguez-Lafrasse
Publikováno v:
Cancers, Vol 13, Iss 15, p 3833 (2021)
Hypoxia-Inducible Factor 1α (HIF-1α), which promotes cancer cell survival, is the main regulator of oxygen homeostasis. Hypoxia combined with photon and carbon ion irradiation (C-ions) stabilizes HIF-1α. Silencing HIF-1α under hypoxia leads to su
Externí odkaz:
https://doaj.org/article/8ca5e27fc78d4a77b39ddc35942c2c7d
Autor:
Anne-Sophie Wozny, Guillaume Vares, Gersende Alphonse, Alexandra Lauret, Caterina Monini, Nicolas Magné, Charlotte Cuerq, Akira Fujimori, Jean-Claude Monboisse, Michael Beuve, Tetsuo Nakajima, Claire Rodriguez-Lafrasse
Publikováno v:
Cancers, Vol 11, Iss 4, p 468 (2019)
Although conventional radiotherapy promotes the migration/invasion of cancer stem cells (CSCs) under normoxia, carbon ion (C-ion) irradiation actually decreases these processes. Unraveling the mechanisms of this discrepancy, particularly under the hy
Externí odkaz:
https://doaj.org/article/186deb7eace64147ad805372bbea07e2
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3855 (2018)
Radiation has a wide variety of effects on the liver. Fibrosis is a concern in medical fields as one of the acute effects of high-dose irradiation, such as with cancer radiotherapies. Cancer is also an important concern following exposure to radiatio
Externí odkaz:
https://doaj.org/article/9898c308bc7f4b318323be9a33d45707
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146730 (2016)
Sake is a traditional Japanese alcoholic beverage that is gaining popularity worldwide. Although sake is reported to have beneficial health effects, it is not known whether chronic sake consumption modulates health risks due to radiation exposure or
Externí odkaz:
https://doaj.org/article/351d34f1790e4cc9a7554a8f6a1578a0
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106277 (2014)
Both exposure to ionizing radiation and obesity have been associated with various pathologies including cancer. There is a crucial need in better understanding the interactions between ionizing radiation effects (especially at low doses) and other ri
Externí odkaz:
https://doaj.org/article/beead1950e534c90a951532346ef0c1c
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77124 (2013)
Exposure to ionizing radiation was shown to result in an increased risk of breast cancer. There is strong evidence that steroid hormones influence radiosensitivity and breast cancer risk. Tumors may be initiated by a small subpopulation of cancer ste
Externí odkaz:
https://doaj.org/article/228df80e292e4e85b2649f30a13c1f97
Publikováno v:
Anticancer Research. 43:2551-2559