Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Tetsuo, Nakata"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1087-1097 (2021)
Cardiotoxicity is one of the severe adverse effects of chemotherapeutic agents. Imatinib was previously reported to induce cardiotoxicity. Autophagy is an intracellular bulk protein and organelle degradation process, but its roles in cardiac diseases
Externí odkaz:
https://doaj.org/article/a01a577eb34345d996ad368672d38855
Autor:
Giuseppe Pezzotti, Miyuki Kobara, Tamaki Nakaya, Hayata Imamura, Tenma Asai, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Ichiro Nishimura, Osam Mazda, Tetsuo Nakata, Koichi Makimura
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The multidrug-resistant Candida auris often defies treatments and presently represents a worldwide public health threat. Currently, the ergosterol-targeting Amphotericin B (AmB) and the DNA/RNA-synthesis inhibitor 5-flucytosine (5-FC) are the two mai
Externí odkaz:
https://doaj.org/article/e09073b8962c42fe96b22c69057da2f2
Autor:
Giuseppe Pezzotti, Miyuki Kobara, Tenma Asai, Tamaki Nakaya, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Ichiro Nishimura, Osam Mazda, Tetsuo Nakata, Koichi Makimura
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Invasive fungal infections caused by yeasts of the genus Candida carry high morbidity and cause systemic infections with high mortality rate in both immunocompetent and immunosuppressed patients. Resistance rates against antifungal drugs vary among C
Externí odkaz:
https://doaj.org/article/31f168ccdaa0442497712b183394fe63
Autor:
Giuseppe Pezzotti, Miyuki Kobara, Tamaki Nakaya, Hayata Imamura, Tomoya Fujii, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Toshihisa Kawai, Osam Mazda, Tetsuo Nakata, Koichi Makimura
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11736 (2022)
This study targets on-site/real-time taxonomic identification and metabolic profiling of seven different Candida auris clades/subclades by means of Raman spectroscopy and imaging. Representative Raman spectra from different Candida auris samples were
Externí odkaz:
https://doaj.org/article/25130390c92b42349dd0ecc42e171a1c
Autor:
Takashi Koizumi, Katsutoshi Taguchi, Ikuko Mizuta, Hiroe Toba, Makoto Ohigashi, Okihiro Onishi, Kazuya Ikoma, Seiji Miyata, Tetsuo Nakata, Masaki Tanaka, Sébastien Foulquier, Harry W. M. Steinbusch, Toshiki Mizuno
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Microglia play crucial roles in the maintenance of brain homeostasis. Activated microglia show a biphasic influence, promoting beneficial repair and causing harmful damage via M2 and M1 microglia, respectively. It is well-known th
Externí odkaz:
https://doaj.org/article/2ac3ba0aeded49a8a1a8a69f325d216d
Autor:
Giuseppe Pezzotti, Miyuki Kobara, Tamaki Nakaya, Hayata Imamura, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Ichiro Nishimura, Osam Mazda, Tetsuo Nakata, Koichi Makimura
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5359 (2022)
Oral candidiasis, a common opportunistic infection of the oral cavity, is mainly caused by the following four Candida species (in decreasing incidence rate): Candida albicans, Candida glabrata, Candida tropicalis, and Candida krusei. This study offer
Externí odkaz:
https://doaj.org/article/b38b78955a744d3fa63683a3bf94089f
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 49:1342-1351
Autophagy is a self-degradation process of cytoplasmic components and occurs in the failing heart. Angiotensin II plays a critical role in the progression of heart failure and induces autophagy. We investigated the mechanism underlying angiotensin II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4f2b54c4548baec06949b6336286ed
https://doi.org/10.1111/1440-1681.13719
https://doi.org/10.1111/1440-1681.13719
Publikováno v:
Cardiovascular Drugs and Therapy. 37:53-62
Ventricular arrhythmias (VAs) are a common cause of sudden death in acute myocardial infarction (MI), for which hypertension is a major risk factor. Nicorandil opens ATP-sensitive potassium (KATP) channels, which are expressed by nerve terminals and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cb075fa5e954b6fbf5e27877ebc53b
https://doi.org/10.1007/s10557-022-07369-1
https://doi.org/10.1007/s10557-022-07369-1
Publikováno v:
Nutrients, Vol 13, Iss 3, p 737 (2021)
Left ventricular (LV) hypertrophy and associated heart failure are becoming a more prevalent and critical public health issue with the aging of society, and are exacerbated by reactive oxygen species (ROS). Dietary restriction (DR) markedly inhibits
Externí odkaz:
https://doaj.org/article/28a09ead9bb34f3bbe7ba3b913071d04
Publikováno v:
Pharmacology. 107:188-196
Introduction: Angelica acutiloba is one of the crude drugs used in Chinese herbal medicine, and its intake is expected to improve metabolic syndrome-associated disorders. Here, we examined the effects of A. acutiloba extract (AAE) on hypertension and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f42a534837908e813ea291df853142b2
https://doi.org/10.1159/000520982
https://doi.org/10.1159/000520982