Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tetsuko Hase"'
Publikováno v:
Chemischer Informationsdienst. 14
In order to study the structure-activity relationship of sparsomycin, an antitumor antibiotic, 26 sparsomycin-related compounds (3-5) were synthesized and their antibacterial activities and lytic actions on Ehrlich ascites carcinoma cells were tested
Publikováno v:
Chemicalpharmaceutical bulletin. 32(11)
In order to study the structure-activity relationship of sparsomycin, an antitumor antibiotic, 26 sparsomycin analogs (3-5) were synthesized and their antibacterial activities and lytic actions on Ehrlich ascites carcinoma cells were tested. It was f
Sparsomycin analogs. II. Synthesis and biological activities of 5-carboxy-6-methyluracil derivatives
Publikováno v:
Chemicalpharmaceutical bulletin. 31(1)
In order to study the structure-activity relationship of sparsomycin, an antitumor antibiotic, 26 sparsomycin-related compounds (3-5) were synthesized and their antibacterial activities and lytic actions on Ehrlich ascites carcinoma cells were tested
Autor:
Akimori Wada, S. Kanatomo, S. Fukuda, M. Yomei, Sotoo Nagai, M. Tanaka, Tetsuko Hase, Takuma Sasaki
Publikováno v:
ChemInform. 20
Autor:
Sotoo Nagai, Takuma Sasaki, Motohiro Tanaka, Kazuhiro Ohki, Shoichi Kanatomo, Tetsuko Hase, Akimori Wada
Publikováno v:
Chemicalpharmaceutical bulletin. 37(3)
Five sparsomycin analogs (9-13) were prepared and examined for their ability to inhibit deoxyribonucleic acid (DNA) synthesis in L5178Y lymphoma cells. All of the compounds showed significant activity in the DNA synthesis assay. The compounds having
Publikováno v:
Chemischer Informationsdienst. 12
Methods for the synthesis of 5-carboxy-6-methyluracil (9), which is expected to be useful as an intermediate for the preparation of sparsomycin analogs, were investigated. A new route that leads to 9 from cyanoacetylurea (5) via 2-cyano-3-oxobutanoyl
Autor:
Tetsuko Hase, Sotoo Nagai, Shizuo Fukuda, Motohiro Tanaka, Masakatsu Yomei, Akimori Wada, Takuma Sasaki, Shoichi Kanatomo
Publikováno v:
Chemicalpharmaceutical bulletin. 36(6)
Synthese et etude biologique des composes du titre N-substitues par carboxy-1'-, methoxycarbonyl-1'- ou hydroxymethyl-1' alkyl, la partie pyrimidine etant elle-meme substituee par dimethoxy-2,4 methyl-6 ou dioxo-1,3 tetrahydro-1,2,3,4 trimethyl-1,3,6
Publikováno v:
Synthesis. 1986:555-556