Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Tetsuhito, Kojima"'
Autor:
Naruko Suzuki, Nobuaki Suzuki, Yuka Kawaguchi, Shuichi Okamoto, Takeshi Kanematsu, Akira Katsumi, Atsuo Suzuki, Shogo Tamura, Tetsuhito Kojima, Hitoshi Kiyoi, Tadashi Matsushita
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Background Tranexamic acid (TXA) is an antifibrinolytic drug that blocks lysine-binding sites on the profibrinolytic enzyme plasminogen. Aortic diseases with chronic consumption coagulopathy may lead to disseminated intravascular coagulation
Externí odkaz:
https://doaj.org/article/9a3f09e237124108a2298eb6be12da63
Autor:
Atsuo Suzuki, Nobuaki Suzuki, Takeshi Kanematsu, Sho Shinohara, Hiroshi Kurono, Nobuo Arai, Shuichi Okamoto, Naruko Suzuki, Shogo Tamura, Ryosuke Kikuchi, Akira Katsumi, Tetsuhito Kojima, Tadashi Matsushita
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Plasma fibrinogen is commonly examined by Clauss fibrinogen assay, which cannot distinguish between quantitative and qualitative fibrinogen anomalies. However, our previously reported Clauss fibrinogen assay utilizing clot waveform analysis
Externí odkaz:
https://doaj.org/article/bab0b468fae849ba97a1aa9089dfc33a
Autor:
Mahiru Tokoro, Shogo Tamura, Nobuaki Suzuki, Misaki Kakihara, Yuna Hattori, Koya Odaira, Sachiko Suzuki, Akira Takagi, Akira Katsumi, Fumihiko Hayakawa, Shuichi Okamoto, Atsuo Suzuki, Takeshi Kanematsu, Tadashi Matsushita, Tetsuhito Kojima
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Hemophilia A (HA) is an X‐linked recessive bleeding disorder caused by pathogenic variants of the coagulation factor VIII gene (F8). Half of the patients with severe HA have a recurrent inversion in the X chromosome, that is, F8
Externí odkaz:
https://doaj.org/article/c36a585e4f024cb4b01c8505cea70a62
Autor:
Shuichi Okamoto, Shogo Tamura, Naomi Sanda, Koya Odaira, Yuri Hayakawa, Masato Mukaide, Atsuo Suzuki, Takeshi Kanematsu, Fumihiko Hayakawa, Akira Katsumi, Hitoshi Kiyoi, Tetsuhito Kojima, Tadashi Matsushita, Nobuaki Suzuki
Publikováno v:
Journal of Thrombosis and Haemostasis. 20(8):1784-1796
Background: Von Willebrand factor (VWF) is a multimeric glycoprotein that plays important roles in hemostasis and thrombosis. C-terminal interchain-disulfide bonds in the cystine knot (CK) domain are essential for VWF dimerization. Previous studies h
Autor:
Shuichi Okamoto, Nobuaki Suzuki, Atsuo Suzuki, Sachiko Suzuki, Shogo Tamura, Mochihito Suzuki, Nobunori Takahashi, Toshihisa Kojima, Takeshi Kanematsu, Tetsuhito Kojima, Hitoshi Kiyoi, Naoki Ishiguro, Tadashi Matsushita
Publikováno v:
TH Open, Vol 03, Iss 04, Pp e364-e366 (2019)
We managed perioperative hemostasis for a 72-year-old man with hemophilia A and low inhibitor titers (3 BU/mL), who underwent osteosynthesis for supracondylar fracture of the left humerus. He was treated perioperatively using the combination of high
Externí odkaz:
https://doaj.org/article/012056557f67465d8e017da3023608cd
Autor:
Yukino Kojima, Fumika Kawashima, Takahiko Yasuda, Koya Odaira, Yuichiro Inagaki, Chiharu Yamada, Ami Muraki, Mina Noura, Shuichi Okamoto, Shogo Tamura, Eisuke Iwamoto, Masashi Sanada, Itaru Matsumura, Yasushi Miyazaki, Tetsuhito Kojima, Hitoshi Kiyoi, Shinobu Tsuzuki, Fumihiko Hayakawa
Publikováno v:
International Journal of Hematology.
Autor:
Koya Odaira, Fumika Kawashima, Shogo Tamura, Nobuaki Suzuki, Mahiru Tokoro, Yuri Hayakawa, Atsuo Suzuki, Takeshi Kanematsu, Shuichi Okamoto, Akira Takagi, Akira Katsumi, Tadashi Matsushita, Midori Shima, Keiji Nogami, Tetsuhito Kojima, Fumihiko Hayakawa
Publikováno v:
Thrombosis Research. 213:91-96
Hemophilia B (HB) is a hereditary bleeding disorder caused by the genetic variation of the coagulation factor IX (FIX) gene (F9). Several F9 structural abnormalities, including large deletion and/or insertion, have been observed to cause HB developme
Autor:
Koya Odaira, Takahiko Yasuda, Kentaro Okada, Takuya Shimooka, Yukino Kojima, Mina Noura, Shogo Tamura, Shingo Kurahashi, Eisuke Iwamoto, Masashi Sanada, Itaru Matsumura, Yasushi Miyazaki, Tetsuhito Kojima, Hitoshi Kiyoi, Shinobu Tsuzuki, Fumihiko Hayakawa
Publikováno v:
Cancer scienceREFERENCES.
CEBPA-IGH, a fusion gene of the immunoglobulin heavy-chain locus (IGH) and the CCAAT enhancer-binding protein α (C/EBPα) gene, is recurrently found in B-ALL cases and causes aberrant expression of C/EBPα, a master regulator of granulocyte differen
Autor:
Masayuki Ochiai, Reiko Neki, Eriko Morishita, Tomoko Adachi, Shouichi Ohga, Takao Kobayashi, Tetsuhito Kojima, Toshiyuki Miyata, Hiroko Tsuda
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 47:3008-3033
Hereditary thrombophilia is a condition in which individuals are susceptible to the formation of thrombi due to a hereditary deficiency in anticoagulant factors, antithrombin (AT), protein C (PC), or protein S (PS). Many Japanese thrombophilia patien
Autor:
Shogo Tamura, Nobuaki Suzuki, Koya Odaira, Yuri Hayakawa, Fumika Kawashima, Atsuo Suzuki, Takeshi Kanematsu, Akira Katsumi, Tadashi Matsushita, Mahiru Tokoro, Shuichi Okamoto, Akira Takagi, Tetsuhito Kojima, Fumihiko Hayakawa
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:920-930
Background Coagulation factor XI (FXI) is a plasma serine protease zymogen that contributes to hemostasis. However, the mechanism of its secretion remains unclear. Objective To determine the molecular mechanism of FXI secretion by characterizing a no