Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tetsuhiro Yokonishi"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Sertoli cells and other somatic cells of the testis comprise the germ cell niche and are critical to regulate spermatogenesis. Here the authors present a method in which Sertoli cells are selectively targeted for ablation by the compound benzalkonium
Externí odkaz:
https://doaj.org/article/7e1fa12214124896b8ec0c7085d0d0b3
Autor:
Takuya Sato, Tetsushi Sakuma, Tetsuhiro Yokonishi, Kumiko Katagiri, Satoshi Kamimura, Narumi Ogonuki, Atsuo Ogura, Takashi Yamamoto, Takehiko Ogawa
Publikováno v:
Stem Cell Reports, Vol 5, Iss 1, Pp 75-82 (2015)
Mouse spermatogonial stem cells (SSCs) can be cultured for multiplication and maintained for long periods while preserving their spermatogenic ability. Although the cultured SSCs, named germline stem (GS) cells, are targets of genome modification, th
Externí odkaz:
https://doaj.org/article/0b49fbabe3c0422da65554e1b025f794
Autor:
Tetsuhiro, Yokonishi
Publikováno v:
Folia Pharmacologica Japonica. 157:168-171
Infertility is one of the late side effects of cancer treatment. Expansion of anti-cancer treatment allow patients to have more life time, however infertility is becoming a matter damaging QOL during the young cancer survivors. The passive strategy s
Autor:
Blanche Capel, Jack D. Keene, Sofia Batchvarova, Josiah Hardy, Victor A. Ruthig, Tetsuhiro Yokonishi, Jason A. Garness, Matthew B Friedersdorf
Publikováno v:
Biol Reprod
In vertebrates, the RNA-binding protein (RBP) dead end 1 (DND1) is essential for primordial germ cell (PGC) survival and maintenance of cell identity. In multiple species, Dnd1 loss or mutation leads to severe PGC loss soon after specification or, in
Autor:
Naoki Aizawa, Tetsuhiro Yokonishi
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 157(3)
Autor:
Blanche Capel, Tetsuhiro Yokonishi
Publikováno v:
Reproduction
Sertoli cells proliferate and construct seminiferous tubules during fetal life, then undergo differentiation and maturation in the prepubertal testes. In the adult testes, mature Sertoli cells maintain spermatogonia and support spermatogenesis during
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Spermatogonia, which produce sperm throughout the male lifetime, are regulated inside a niche composed of Sertoli cells, and other testis cell types. Defects in Sertoli cells often lead to infertility, but replacement of defective cells has been limi
Autor:
Blanche Capel, Tetsuhiro Yokonishi
Publikováno v:
Journal of Urology. 201
Autor:
Tetsuhiro Yokonishi, Blanche Capel
Publikováno v:
Reproduction; Aug2021, Vol. 162 Issue 2, p141-147, 7p
Autor:
Kazuaki Kojima, Hiroyuki Yamanaka, Kumiko Katagiri, Masahiro Yao, Hiroko Nakamura, Narumi Ogonuki, Takehiko Ogawa, Kazuaki Hayashi, Satoshi Kamimura, Teruo Fujii, Tetsuhiro Yokonishi, Hiroyuki Sanjo, Takuya Sato, Mitsuru Komeya, Kimiko Inoue, Atsuo Ogura, Hiroshi Kimura
Publikováno v:
Scientific Reports
In contrast to cell cultures, particularly to cell lines, tissues or organs removed from the body cannot be maintained for long in any culture conditions. Although it is apparent that in vivo regional homeostasis is facilitated by the microvascular s