Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tetsuhiro Kimura"'
Autor:
Katsutoshi Inaba, Goto Hiroshi, Shinichi Kaneda, Tetsuhiro Kimura, Takanobu Ishizuka, Hiroaki Kasukawa
Publikováno v:
Artificial Organs. 33:146-152
Clinical application of artificial oxygen carriers as a substitute for blood transfusion has long been expected to solve some of the problems associated with blood transfusion. Use for oxygen delivery treatment for ischemic disease by oxygen delivery
Publikováno v:
The Journal of Physical Chemistry C. 112:13232-13239
Molecular structures at the free surface of liquid n-heptadecane (n-C17H36; freezing point (Tf) 22 °C, surface freezing point (Ts) 24 °C) were studied by infrared external reflection spectroscopy. ...
Publikováno v:
Journal of Artificial Organs. 8:263-269
Hypothermia decreases cerebral metabolism and increases hemoglobin oxygen affinity. A hypothesis that the reversal of increased oxygen affinity would further attenuate hypothermic cerebral ischemia was tested by evaluating the effects of liposome-enc
Publikováno v:
Journal of Artificial Organs. 7:19-26
It has been reported that retrograde cerebral perfusion (RCP) provides minimal capillary flow; however, the extent to which RCP can provide aerobic metabolic support is unknown. We evaluated whether perfusate composition optimization for RCP would pr
Autor:
Fumihiko Osuka, Hideo Fukui, Tetsuhiro Kimura, Ryoh Sato, Takashi Kimura, Akira Usuba, Yoshitaka Ogata, Hiroshi Gotoh
Publikováno v:
Surgery Today. 28:1027-1035
We examined the effects of liposome-encapsulated hemoglobin, neo red cells (NRCs), on hemorrhagic shock in a canine model. The dogs were divided into the three groups according to treatment. In group 1, composed of six dogs, NRCs were substituted for
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 26:477-485
The hemoglobin oxidation factors that produce methemoglobin (metHb) were studied, for example, loss of enzymatic activity, lack of electron carrier and effect of lipids. The adverse effect of lipids is very pronounced and must be eliminated as much a
Autor:
Goto Hiroshi, Yoshikazu Asakawa, Yoshitaka Ogata, Toshiharu Kamitani, Youji Tsutsui, Tetsuhiro Kimura, Noriko Ohki
Publikováno v:
membrane. 20:282-286
We have developed and evaluated the liposome encapsulated high-concentrated (>45%) stroma free hemoglobin (SFH) : Neo Red Cell (NRC). SFH was encapsulated together with inositol-hexaphosphate (as an allosteric effector), coenzyme and substrates for r
Autor:
Hideki Obika, Yoshitsugu Ueda, Yoshinari Kobayashi, Keiko Takahashi, Tetsuhiro Kimura, Keisuke Tsuji
Publikováno v:
Journal of the agricultural chemical society of Japan. 67:1177-1183
(1) In vitroにおいて中和反応によるH-AlgのNa吸着量は100mg/g,最大吸着量の77%であった.イオン交換反応によるK-AlgのNa吸着量は45mg/g,最大吸着量の42%であった. (2) In vivoにおいては, H-AlgおよびK-Alg
Publikováno v:
Nippon Eiyo Shokuryo Gakkaishi. 46:429-433
摂取アルギン酸 (H-A1g) のヒトにおける糞便中Na排泄促進作用について検討した。その結果, 次の点が明らかとなった。1) 糞便中に排泄されたA1gは, ほぼ一定量のNaを吸着し, 糞便中Na排泄量
Publikováno v:
Journal of Artificial Organs. 7
Liposome-encapsulated hemoglobin (LipoHb) with low oxygen affinity (P(50) = 40-50 mmHg) has been developed. The purpose of this study was to evaluate the effects of the LipoHb on incomplete cerebral ischemia. Wistar rats were randomly assigned to one