Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tetsuhiko Yanazume"'
Publikováno v:
Journal of Cardiology Cases. 9(1):29-31
A 69-year-old woman with exertional dyspnea was referred emergently to our hospital for further evaluation. Transthoracic echocardiography showed severe mitral valve regurgitation and moderate tricuspid regurgitation, which were thought to be the mai
Autor:
Teruhisa Kawamura, Tatsuya Morimoto, Maretoshi Hirai, Tetsuhiko Yanazume, Toru Kita, Mitsuru Abe, Koji Hasegawa, Hiromichi Wada, Yutaka Furukawa
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:404-410
Objective— Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the nuclear receptor superfamily involved in the growth and differentiation of many cell types. Although the activation of PPARγ in human vascular smooth muscle cells
Publikováno v:
Molecular and Cellular Biochemistry. 248:115-119
A cellular target of adenovirus E1A oncoprotein, p300 is a transcriptional coactivator required for the maintenance of differentiated phenotypes in cardiac myocytes. The full transcriptional activities of hypertrophy-responsive transcription factors
Autor:
Tsuyoshi Kakita, Hiromichi Wada, Koji Hasegawa, Shigetake Sasayama, Mitsuru Abe, Tetsuhiko Yanazume, Tatsuya Morimoto
Publikováno v:
The Journal of Cell Biology
Intracellular calcium is one of the important signals that initiates the myogenic program. The calcium-activated phosphatase calcineurin is necessary for the nuclear import of the nuclear factor of activated T cell (NFAT) family members, which intera
Autor:
Tatsuya Sawamura, Yasuki Kihara, Eri Iwai-Kanai, Koji Hasegawa, Tetsuhiko Yanazume, Masatoshi Fujita, Shinya Toyokuni, Souichi Adachi, Shigetake Sasayama
Publikováno v:
Circulation. 104:2948-2954
Background — Lectin-like oxidized LDL receptor-1 (LOX-1) was originally identified as a receptor expressed predominantly in endothelial cells. LOX-1 can also be expressed in other cell types, and the activation of the LOX-1 pathway has been implica
Publikováno v:
Molecular and cellular biochemistry. 248(1-2)
A cellular target of adenovirus E1A oncoprotein, p300 is a transcriptional coactivator required for the maintenance of differentiated phenotypes in cardiac myocytes. The full transcriptional activities of hypertrophy-responsive transcription factors
Autor:
Tetsuhiko Yanazume, Yosuke Kawase, Teruhisa Kawamura, Toru Kita, Maretoshi Hirai, Tatsuya Morimoto, Koji Hasegawa, Akira Matsumori, Hiromichi Wada
Publikováno v:
Molecular and cellular biology. 23(10)
A variety of stresses on the heart initiate a number of subcellular signaling pathways, which finally reach the nuclei of cardiac myocytes and cause myocyte hypertrophy with heart failure. However, common nuclear pathways that lead to this state are
Autor:
Toru Kita, Koji Hasegawa, Tetsuhiko Yanazume, Masatoshi Fujita, Teruhisa Kawamura, Eri Iwai-Kanai, Taku Hirai, Kazuaki Kataoka, Tatsuya Sawamura, Ryuji Nohara
Publikováno v:
Biochemical and biophysical research communications. 300(3)
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) was originally identified as a receptor for oxidized low-density lipoprotein predominantly expressed in endothelial cells. LOX-1 expression can be induced in cardiomyocytes and that acti
Autor:
Tetsuhiko Yanazume, Koji Hasegawa, Shigetake Sasayama, Hiromichi Wada, Mitsuru Abe, Tatsuya Morimoto, Teruhisa Kawamura
Publikováno v:
The Journal of biological chemistry. 277(10)
The low molecular weight GTPase Rho mediates a variety of cytoskeleton-dependent cell functions and stretch- and G(q) protein-induced hypertrophic responses in cardiac myocytes. Although ROCK, one of Rho's effectors, has been suggested to mediate hyp
Autor:
Satoshi Kaburagi, Tatsuya Morimoto, Tsuyoshi Kakita, Shigetake Sasayama, Tetsuhiko Yanazume, Hiromichi Wada, Koji Hasegawa
Publikováno v:
The Journal of biological chemistry. 276(37)
Increases in the expression of endothelin-1 (ET-1) in cardiac myocytes play a critical role in the development of heart failure in vivo. Whereas norepinephrine (NE) is a potent inducer of ET-1 expression in cardiac myocytes, the signaling pathways th