Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tetsuharu Shinjyo"'
Autor:
Nobuyuki Takasu, Tetsuharu Shinjyo, Hirotaka Matsui, Akitoshi Nagasaki, Yusuke Furukawa, Jun-ichi Miyagi, Kiyoto Ohama, Masato Masuda, Hidemitsu Kurosawa, Toshiya Inaba
Publikováno v:
The Tohoku Journal of Experimental Medicine. 216:25-34
Survivin, a member of the inhibitor of apoptosis protein (IAP) family, has been widely studied because of its aberrant expression in human cancer. Survivin has multiple functions, including cell-cycle regulation at mitosis, inhibition of apoptosis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760a7cb651f9facd1adff3e7fa3bcc27
https://doi.org/10.1620/tjem.216.25
https://doi.org/10.1620/tjem.216.25
Autor:
Tetsuharu Shinjyo, Yoshinori Shimajiri, Nobuyuki Takasu, Michio Shimabukuro, Toshiya Inaba, Moritake Higa
Publikováno v:
Diabetes, Obesity and Metabolism. 8:228-233
Aim: This study was conducted to clarify cell death and survival signals in pancreatic β-cell lipotoxicity. Methods: Rat insulinoma INS-1 cells, with or without expression of dominant-negative mutant of Akt (K179M), were cultured with palmitate (C16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f49d853a49d57a33e53d4d3544ef364
https://doi.org/10.1111/j.1463-1326.2005.00488.x
https://doi.org/10.1111/j.1463-1326.2005.00488.x
Autor:
Takeshi Inukai, Hirotaka Matsui, Tetsuharu Shinjyo, Shinpei Nakazawa, Ryoko Kuribara, Toshiya Inaba, Keiya Ozawa, Hiroaki Honda, Kanji Sugita, Hisamaru Hirai
Publikováno v:
Molecular and Cellular Biology. 24:6172-6183
Bcr-Abl kinase is known to reverse apoptosis of cytokine-dependent cells due to cytokine deprivation, although it has been controversial whether chronic myeloid leukemia (CML) progenitors have the potential to survive under conditions in which there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781b024afb0a98b548d6a6cf4651a81f
https://doi.org/10.1128/mcb.24.14.6172-6183.2004
https://doi.org/10.1128/mcb.24.14.6172-6183.2004
Autor:
Akitoshi Nagasaki, Tetsuharu Shinjyo, Hiroshi Uezato, Jun-ichi Miyagi, Naoki Kakazu, Yuetsu Tanaka, Nobuyuki Takasu, Masato Masuda
Publikováno v:
International Journal of Hematology. 76:165-172
Primary effusion lymphoma (PEL) is recognized as a unique lymphoma entity, which occurs exclusively in body cavities as a serous lymphomatous effusion without tumor formation or organ infiltration. We established a cell line of B-cell origin from a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594761f9abd49c311dde44301ed01c81
https://doi.org/10.1007/bf02982580
https://doi.org/10.1007/bf02982580
Autor:
Takeshi Inukai, Ryoko Kuribara, Toshiya Inaba, H Hosoi, Atsushi Miyajima, Tetsuharu Shinjyo, Keiya Ozawa, Peter J. Houghton, A T Look, Taisei Kinoshita
Publikováno v:
Molecular and Cellular Biology. 21:854-864
Two distinct signaling pathways regulate the survival of interleukin-3 (IL-3)-dependent hematopoietic progenitors. One originates from the membrane-proximal portion of the cytoplasmic domain of the IL-3 receptor (betac chain), which is shared by IL-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b46fd1da691167bcd3ab87474223fe
https://doi.org/10.1128/mcb.21.3.854-864.2001
https://doi.org/10.1128/mcb.21.3.854-864.2001
Autor:
Toshiya Inaba, Ryoko Kuribara, Takeshi Inukai, A. Thomas Look, Atsushi Miyajima, Taisei Kinoshita, Takao Yoshihara, Tetsuharu Shinjyo, Keiya Ozawa
Publikováno v:
Molecular and Cellular Biology. 19:2754-2762
Hematopoietic cells require cytokine-initiated signals for survival as well as proliferation. The pathways that transduce these signals, ensuring timely regulation of cell fate genes, remain largely undefined. The NFIL3 (E4BP4) transcription factor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efda925275361872ee8f4c588b06681b
https://doi.org/10.1128/mcb.19.4.2754
https://doi.org/10.1128/mcb.19.4.2754
Autor:
Toshiya Inaba, Clayton W. Naeve, Karen M. Rakestraw, Kumiko Goi, Kun-San Chang, Tetsuharu Shinjyo, A. Thomas Look, Hidemitsu Kurosawa, T Inukai
Publikováno v:
Blood. 93:321-332
The E2A-HLF fusion gene, formed by the t(17;19)(q22;p13) chromosomal translocation, is thought to drive the leukemic transformation of early B-cell precursors by repressing an evolutionarily conserved apoptotic pathway. To test this hypothesis, we so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2718e59891c2e0fb02d7401a0ef30b28
https://doi.org/10.1182/blood.v93.1.321
https://doi.org/10.1182/blood.v93.1.321
Autor:
Naoya Taira, Jun-ichi Miyagi, Nobuyuki Takasu, Tetsuharu Shinjyo, Tamiko Taira, Masato Masuda, Takeaki Tomoyose, Akitoshi Nagasaki, Naoki Kakazu, Shigeyoshi Makino
Publikováno v:
Leukemia research. 31(9)
A new cell line, STR-428 was established from ascites tumor cells of a malignant effusion lymphoma patient without human herpes virus-8 (HHV-8) infection. STR-428 cells showed an immunophenotype of mature B-cells and produced few cytokines related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cbcdc30134e127543feeffc9405f59
https://pubmed.ncbi.nlm.nih.gov/17544119
https://pubmed.ncbi.nlm.nih.gov/17544119
Publikováno v:
Molecular biology reports. 32(2)
Deprivation of cytokines induces cell cycle arrest and apoptosis in cytokine-dependent hematopoietic progenitors. Previous studies have indicated that in Baf-3, interleukin (IL)-3-dependent cells, apoptosis is caused predominantly by Bim, a BH3-only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b053fb8569f350df48a70b78eac2b5e4
https://pubmed.ncbi.nlm.nih.gov/16022280
https://pubmed.ncbi.nlm.nih.gov/16022280
Autor:
Tetsuro Nakazato, Naoya Taira, Masato Masuda, Tetsuharu Shinjyo, Takeaki Tomoyose, Nobuyuki Takasu, Tatsuo Abe, Naoki Kakazu, Akitoshi Nagasaki, Misao Ohki, Tamiko Toyohama, Takashi Miyagi, Jun-ichi Miyagi
Publikováno v:
International journal of hematology. 76(4)
We report a case of acute myeloid leukemia (AML), M2 subtype according to the French-American-British (FAB) classification, with extramedullary myeloblastoma of the uterus and a masked type of variant translocation of t(8;21)(q22;q22). A 45-year-old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b5aefe1255a5af788961b5ddd6d54e
https://pubmed.ncbi.nlm.nih.gov/12463597
https://pubmed.ncbi.nlm.nih.gov/12463597