Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tetsuaki Sekikawa"'
Autor:
Nobuakira Takeda, Tetsuaki Sekikawa, Junko Horiguchi-Yamada, Shinobu Takahara, Hisashi Yamada, Hideaki Suzuki
Publikováno v:
European Journal of Haematology. 78:264-269
Richter's syndrome occurs in 5-10% of patients with chronic lymphocytic leukemia, either by transformation of the primary neoplastic lymphocyte, or as a distinct B-cell neoplasm. We report a Japanese patient with lymphoplasmacytic lymphoma in whom a
Autor:
Tetsuaki Sekikawa, Shuji Nakada, Satsuki Iwase, Kiyoshi Ito, Masayuki Kobayashi, Shinobu Takahara, Takeshi Kawano, Hisashi Yamada, Junko Horiguchi-Yamada
Publikováno v:
International Journal of Hematology. 76:453-459
B-cell diseases are classified on the basis of the normal differentiation stages. We report here a case of a patient with a long history of leukocytosis, splenomegaly without lymphadenopathy, and hyperviscosity symptoms. Clinically, the patient's dia
Autor:
Satsuki Iwase, Mayumi Takao, Hiroshi Ideguchi, Tetsuaki Sekikawa, Shinobu Takahara, Hisashi Yamada, Masafumi Iwasaki, Seibu Mochizuki, Junko Horiguchi-Yamada
Publikováno v:
Acta Haematologica. 100:200-203
We report a case of spherocytosis associated with erythrocyte band 3 deficiency. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of erythrocyte membrane proteins showed that the patient’s band 3 was reduced to about 80% of the control lev
Autor:
Makoto Nagai, Shinobu Takahara, Junko Horiguchi-Yamada, Satsuki Iwase, Tetsuaki Sekikawa, Takeshi Kawano, Hisashi Yamada, Sachiko Fukumi, Kiyoshi Itoh
Publikováno v:
Molecular and Cellular Biochemistry. 187:211-220
Therapeutic strategies for leukemia are directed to induction of differentiation and apoptosis as well as growth inhibition. One of the key antileukemic agents, 1-β-D-arabinofuranosylcytosine (ara C), is clinically applied according to these therape
Autor:
Tetsuaki Sekikawa
Publikováno v:
Nihon Naika Gakkai Zasshi. 88:2471-2473
Autor:
Hisashi, Yamada, Tetsuaki, Sekikawa, Miyuki, Agawa, Satsuki, Iwase, Hideaki, Suzuki, Junko, Horiguchi-Yamada
Publikováno v:
Anticancer research. 28(1A)
Binding of integrins to the extracellular matrix elicits various responses. We have previously reported a megakaryocytic-erythroid cell line (JAS-R) that showed phenotypic changes after adhesion to plastic dishes. However, the matrix protein and the
Autor:
Junko Horiguchi-Yamada, Satsuki Iwase, Masaharu Akiyama, Nobuakira Takeda, Yasuhiro Arakawa, Hisashi Yamada, Tetsuaki Sekikawa, Hideaki Suzuki, Miyuki Agawa
Publikováno v:
Leukemia research. 31(11)
Adhesion is one of the important biologic characteristics of leukemic cells. We previously reported a new megakaryocytic-erythroid cell line, JAS-R. In this study, JAS-R cells were segregated into two types by the differences of attachment to culture
Autor:
Tetsuaki, Sekikawa, Satsuki, Iwase, Shinobu, Saito, Yasuhiro, Arakawa, Miyuki, Agawa, Junko, Horiguchi-Yamada, Hisashi, Yamada
Publikováno v:
Anticancer research. 26(2A)
The processes of leukemogenesis and differentiation of the megakaryo-erythroid lineage remain poorly understood. Leukemic cell lines derived from megakaryocytic leukemia are valuable reagents for studies on these events.A new cell line, JAS-R, was es
Publikováno v:
Blood. 106:4327-4327
A few leukemic cell lines which express megakaryo/erythroid markers are available. We recently established a new cell line, designated JAS-R, from a 64-year-old patient with acute megakaryocytic leukemia (AML M7). Immunophenotyping showed that JAS-R
Autor:
Tetsuaki Sekikawa, Kiyoshi Ito, Y Yamazaki, Hironori Yamada, Satsuki Iwase, Takeshi Kawano, Yusuke Furukawa, Shinobu Takahara, Jiro Kikuchi, T Nemoto, Junko Horiguchi-Yamada, K Morishita
Publikováno v:
International Journal of Hematology. 67:361
Chromosomal translocation often results in aberrant activation of the genes with oncogenic potential and, thus, plays an important role in leukemogenesis. We report a unique case of acute myelomonocytic leukemia carrying a rare reciprocal translocati