Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tetsuaki Kaku"'
Autor:
Yamato Fukui, Yasushi Hirota, Shizu Aikawa, Akihiko Sakashita, Ryoko Shimizu-Hirota, Norihiko Takeda, Chihiro Ishizawa, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, Takehiro Hiraoka, Shun Akaeda, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract Infertility occurs in 15% of couples worldwide. Recurrent implantation failure (RIF) is one of the major problems in in vitro fertilization and embryo transfer (IVF–ET) programs, and how to manage patients with RIF to achieve successful pr
Externí odkaz:
https://doaj.org/article/7a6eca6a7f744b3f90823466c14b402e
Autor:
Shizu Aikawa, Yasushi Hirota, Yamato Fukui, Chihiro Ishizawa, Rei IIda, Tetsuaki Kaku, Tomoyuki Hirata, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dyn
Externí odkaz:
https://doaj.org/article/a11915835c324e1caf53642f622ab2eb
Autor:
Tetsuaki Kaku, Takehiro Hiraoka, Rei Iida, Chihiro Ishizawa, Mitsunori Matsuo, Tomoyuki Hirata, Shizu Aikawa, Yutaka Osuga, Yamato Fukui, Shun Akaeda, Yasushi Hirota
Publikováno v:
Reproductive Sciences. 29:1457-1462
Recurrent implantation failure is a major problem in assisted reproductive technology (ART). Although ART systems have evolved rapidly over the decades, it is still difficult to diagnose uterine conditions suitable for embryo transfer (ET) without th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5779a3c77e4384ec7bc8d5bf0f8c7f
https://doi.org/10.1007/s43032-021-00816-8
https://doi.org/10.1007/s43032-021-00816-8
Autor:
Tomoyuki Fujii, Yutaka Osuga, Yasushi Hirota, Mona Gebril, Norihiko Takeda, Tomoyuki Hirata, Shizu Aikawa, Ryoko Shimizu-Hirota, Yamato Fukui, Takehiro Hiraoka, Shun Akaeda, Hirofumi Haraguchi, Tetsuaki Kaku, Mayuko Saito-Kanatani, Osamu Yoshino, Mitsunori Matsuo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Although it has been reported that uterine signal transducer and activator of transcription 3 (STAT3) is essential for embryo implantation, the exact roles of uterine epithelial and stromal STAT3 on embryo implantation have not been elucidated. To ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a150b96ecabdec3cf6003683ddbce44
http://link.springer.com/article/10.1038/s41598-020-72640-0
http://link.springer.com/article/10.1038/s41598-020-72640-0
Autor:
Takehiro Hiraoka, Yasushi Hirota, Shizu Aikawa, Rei Iida, Chihiro Ishizawa, Tetsuaki Kaku, Tomoyuki Hirata, Yamato Fukui, Shun Akaeda, Mitsunori Matsuo, Ryoko Shimizu-Hirota, Norihiko Takeda, Yutaka Osuga
Publikováno v:
Endocrinology. 163(5)
Adenomyosis is a benign uterine disease that causes dysmenorrhea, heavy menstrual bleeding, and infertility; however, its pathophysiology remains unclear. Since signal transducer and activator of transcription 3 (STAT3) is crucial for endometrial reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fb717a44f7740a5a18819bb15fba54
https://pubmed.ncbi.nlm.nih.gov/35380652
https://pubmed.ncbi.nlm.nih.gov/35380652
Autor:
Chihiro Ishizawa, Yasushi Hirota, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, Yamato Fukui, Erika Omura, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.).
Levonorgestrel-releasing intrauterine system (LNG-IUS) relieves dysmenorrhea and heavy menstrual bleeding (HMB) in adenomyosis. However, its efficacy on health-related quality of life (HR-QOL) in patients with symptomatic adenomyosis remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b314852c8d3a6bbcadec49e3cc3b4f
https://pubmed.ncbi.nlm.nih.gov/36071343
https://pubmed.ncbi.nlm.nih.gov/36071343
Autor:
Tomoyuki Fujii, Zixin Xu, Yoko Urata, Osamu Wada-Hiraike, Jerilee M K Azhary, Chisato Kunitomi, Emi Nose, Tetsuaki Kaku, Akari Kusamoto, Yutaka Osuga, Miyuki Harada, Nozomi Takahashi, Kaori Koga, Hiroshi Koike, Yasushi Hirota
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(11)
It has been recently recognized that prenatal androgen exposure is involved in the development of polycystic ovary syndrome (PCOS) in adulthood. In addition, the gut microbiome in adult patients and rodents with PCOS differs from that of healthy indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f0131ce3b508aa0e27066cccfd1e81
https://pubmed.ncbi.nlm.nih.gov/34653284
https://pubmed.ncbi.nlm.nih.gov/34653284
Autor:
Yutaka Osuga, Tetsuaki Kaku, Mitsunori Matsuo, Yamato Fukui, Takehiro Hiraoka, Norihiko Takeda, Shun Akaeda, Yasushi Hirota, Masahito Ikawa, Tomoyuki Hirata, Tomoko Saito-Fujita, Shizu Aikawa, Ryoko Shimizu-Hirota
Publikováno v:
Endocrinology. 162
Recent studies have demonstrated that the formation of an implantation chamber composed of a uterine crypt, an implantation-competent blastocyst, and uterine glands is a critical step in blastocyst implantation in mice. Leukemia inhibitory factor (LI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a49b92b46c630cf018ef19fcd853c4
https://doi.org/10.1210/endocr/bqab169
https://doi.org/10.1210/endocr/bqab169
Autor:
Takehiro Hiraoka, Hirofumi Haraguchi, Shun Akaeda, Shizu Aikawa, Ryoko Shimizu-Hirota, Norihiko Takeda, Mitsunori Matsuo, Tomoyuki Hirata, Tomoyuki Fujii, Mona Gebril, Yasushi Hirota, Yamato Fukui, Yutaka Osuga, Tetsuaki Kaku, Mayuko Saito-Kanatani
Publikováno v:
EMBO Rep
Retinoblastoma protein (RB) encoded by Rb1 is a prominent inducer of cell cycle arrest (CCA). The hormone progesterone (P(4)) promotes CCA in the uterine epithelium and previous studies indicated that P(4) activates RB by reducing the phosphorylated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f48ab54e42b14fa54d4cb27383bdb85
https://doi.org/10.15252/embr.202050927
https://doi.org/10.15252/embr.202050927
Autor:
Tomoyuki Hirata, Shizu Aikawa, Tamer Taha, Mona Gebril, Ryoko Shimizu-Hirota, Yutaka Osuga, Mitsunori Matsuo, Tomoyuki Fujii, Takehiro Hiraoka, Osama Al Balah, Norihiko Takeda, Tetsuaki Kaku, Yasushi Hirota, Shun Akaeda, Yamato Fukui, Mohamed Amr. H. Elnoury
Publikováno v:
Endocrinology. 161
Progesterone receptor (PGR) is indispensable for pregnancy in mammals. Uterine PGR responds to the heightened levels of ovarian progesterone (P4) after ovulation and regulates uterine gene transcription for successful embryo implantation. Although ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554f92794983cb2490de7524134caae1
https://doi.org/10.1210/endocr/bqaa195
https://doi.org/10.1210/endocr/bqaa195